NCT01868165|CompletedResults
Loading search results
Sponsor study identifier
observational
337
1 country
7
Study Start
June 2013
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
February 2015
Actual (reported)Study Completion
February 2016
Actual (reported)Older adults are at increased risk of high blood pressure and cognitive decline. High blood pressure itself also increases risk of cognitive decline. A particular type of blood pressure lowering drug (a calcium channel blocker(CCB)) may lower risk of dementia in younger adults but there is no clear evidence of it's impact in those \>=80. It is important that we know whether CCB use impacts on cognitive function in this age group. This study will examine the impact of antihypertensives on change in cognitive function with a particular focus on CCBs.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
February 2016
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 29, 2013
Actual (reported)June 2013
Date type not reportedThis date has not been verified as actual or estimated.
June 4, 2013
Actual (reported)February 2015
Actual (reported)February 2016
Actual (reported)September 23, 2019
Actual (reported)Change in Cognitive Function as Measured Using the Extended Mini Mental State Exam
The change in cognitive function measured using the extended mini-mental state exam (this is an extended screening test which assesses several areas of cognitive function, the scale is from 0-100, higher scores are better, those without cognitive impairment would be expected to score close to maximum)
12 months
Adults aged 80 and over treated with antihypertensive drugs
UK Primary care
The Kiltearn Medical Centre
Nantwich, Cheshire, CW5 5NX, United Kingdom
Ashfields Primary Care Centre
Sandbach, Cheshire, CW11 BEQ, United Kingdom
Whitby Group Practice
Whitby, North Yorkshire, YO21 1SD, United Kingdom
South Axholme Practice
Epworth, Yorkshire, DN9 1EP, United Kingdom
Dr Moss and Partners
Harrogate, HG1 5JP, United Kingdom
Gale Farm Surgery
York, YO24 3BU, United Kingdom
Haxby Group Practice
York, YO32 2LL, United Kingdom
Peters R. No clear relationship between antihypertensive class and cognitive function over 12 months in a cohort study of community-dwelling adults aged 80 and over. Ther Adv Chronic Dis. 2019 Jan 31;10:2040622318820849. doi: 10.1177/2040622318820849. eCollection 2019.
Ruth Peters, PhD
Imperial College London, UK
337 participants (actual enrollment reported by the registry).
First Submitted
May 29, 2013
First Posted
June 4, 2013
Study Start
June 2013
Date type not reportedThis date has not been verified as actual or estimated.
Comparision of Blood Pressure Variability Between Amlodipine and Losartan
Contact the study team to confirm eligibility.
Primary Completion
February 2015
Actual (reported)Study Completion
February 2016
Actual (reported)Last Updated
September 23, 2019
Results First Posted
September 23, 2019
Record last verified: 2019-08
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: