NCT01865344

Brief Summary

To provide a preliminary evaluation of the correlation between Numeric rating Score (NRS) and skin conductance responses per second at rest and in response to a painful stimulus. Sensitivity and specificity will be calculated for NRS and skin conductance responses per sec to a standardized painful stimulus. Furthermore, predictors of pain will be examined.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started May 2013

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2013

Completed
26 days until next milestone

First Submitted

Initial submission to the registry

May 27, 2013

Completed
3 days until next milestone

First Posted

Study publicly available on registry

May 30, 2013

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2013

Completed
Last Updated

December 4, 2013

Status Verified

December 1, 2013

Enrollment Period

5 months

First QC Date

May 27, 2013

Last Update Submit

December 3, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • Skin conductance responses per sec and NRS before and during painful procedures

    * No significant adverse events related to use of the Pain Monitor device * Increase in skin conductance responses per sec and NRS after administration of painful stimulus compared to the non-painful situations.

    8 months

Study Arms (1)

Heart surgery

Pain monitoring at different time periods

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult cardiac patients prior to, during, and after anesthesia for surgery. The proposed pilot study will be conducted at the Acute Clinic, Rikshospitalet - Oslo University hospital, Oslo, Norway.

You may qualify if:

  • Age: Older than 18 years, patients scheduled for cardiac surgery.
  • Patients admitted to the Cardiac Unit with cardiac disease.
  • Patients able to verbally communicate pain level during or after the procedures.
  • Pain medication following institutional standard care; only diazepam given before the painful procedure. During surgery, institutional standard care for sedation will be given.

You may not qualify if:

  • Administration or anesthesia or analgesia other than diazepam prior to evaluation with the PainMonitor.
  • Presence of any neurological disease affecting the peripheral nerves.
  • Abuse of alcohol or illicit drugs
  • History of mental retardation or any mental disease
  • Severe neuropathic disease
  • Use of neostigmine before event 1, 2, and 3, see events below.
  • Use of atropin
  • Use of regional anesthesia at the extremity where the device electrodes are placed.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Acute Clinic, Rikshospitalet - Oslo University hospital

Oslo, 0027, Norway

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Jan F Bugge, MD.PhD

    Head of the Anesthesia Thorax department

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 27, 2013

First Posted

May 30, 2013

Study Start

May 1, 2013

Primary Completion

October 1, 2013

Study Completion

October 1, 2013

Last Updated

December 4, 2013

Record last verified: 2013-12

Locations