Social Skills Group Training ("KONTAKT") for Children and Adolescent With High-functioning Autism Spectrum Disorders

NCT01854346 | Completed

• 1 other identifier: KONTAKT
• Study Type: interventional
• Target: 296
• Locations: 1 country
• Sites: 1

Brief Summary

This trial investigates the behavioral effects of manualized social skills training (KONTAKT) in children´s and adolescents with high-functioning autism spectrum disorder with psychiatric comorbidity in a RCT, multicenter study. N = 288 are recruited from 10 child and adolescent psychiatric clinics in Stockholm County. The examination of genetic variants as predictors for outcome and a qualitative study of KONTAKT complete the trial.

Conditions

Autism Spectrum Disorder (ASD); Attention Deficit Hyperactivity Disorder (ADHD); Anxiety; Depression

Keywords

Autism spectrum disorder; Social skills training; Group training; Comorbidity; Intervention; Evidence-based

Outcome Measures

Primary Outcomes (1)

• Social Responsiveness Scale (SRS)

  Parent and teachers report.

  Baseline, 3 months after training and 3 months follow-up

Secondary Outcomes (4)

• Adaptive Behavior Assessment System II (ABAS II)

  Baseline, 3 months after training and 3 months follow-up

• Developmental Disabilities Modification of the Children's Global Assessment Scale (DD-CGAS)

  Baseline, 3 months after training and 3 months follow-up

• Clinical Global Impression-Improvement/Severity (CGI)

  Baseline, 3 months after training and 3 months follow-up

• Samples With DNA

  2 weeks after the beginning of the treatment

Other Outcomes (2)

• Perceived stress Scale (PSS)

  Baseline, 3 months after training and 3 months follow-up

• Barn Under Stress (BUS)

  Baseline, 3 months after training and 3 months follow-up

Study Arms (2)

Social skills group training KONTAKT

EXPERIMENTAL

N= 144 participants are offered group training KONTAKT. The intervention includes 12 (brief intervention) and 24 (long intervention) sessions.

Behavioral: Social skills group training, KONTAKT

Control group (TAU), the usual intervention / treatment

NO INTERVENTION

N = 144 participants are received treatment as usual (pharmacological therapy, family therapy, Cognitive behavioral therapy etc).

Interventions

Social skills group training, KONTAKT BEHAVIORAL

KONTAKT is a manual-based social skills group training for children with high functioning autism spectrum disorder (ASD). The program is based on cognitive behavioral therapy (CBT) principles and knowledge of social cognition. The group treatment includes exercises in social skills as well as discussions of social cognition, social interaction, self-reflection and description of themselves and others. The children are training to make contact, to understand and follow social rules, to become aware of themselves and others, to perceive verbal and nonverbal signals in a communication, to develop problem solving skills and coping strategies to manage conflict and to enhance their self-confidence. Intervention includes 12 (brief intervention) and 24 (long intervention) sessions. Each group consists of 4-8 children/adolescents ant two group leaders. The treatment are conducted in cooperation with both parents and teachers.

Also known as: Social skills training, Social skills group training, KONTAKT

Social skills group training KONTAKT

Eligibility Criteria

• Age: 8 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Children and adolescent with High-functioning autism (F84.5, F 84.9 according to International Classification of Diseases (ICD-10). Participants have been investigated with the Autism Diagnostic Observation Schedule (ADOS).
• Normal psychometric range of intelligence, intelligence quotient (IQ)\> 70 according to Wechsler Intelligence Scale for Children- Fourth Edition (WISC-IV).
• Comorbid diagnosis: ADHD (F90.0 and F98.8), Anxiety Syndrome (F41.1) and depression (F32.9) according to a best estimate clinical assessment.

You may not qualify if:

• Any behavioral disorder not currently allowing meaningful participation in group-based training for ASD, e.g. presence of clinically diagnosed self-injury, conduct disorder (F91), hyperkinetic conduct disorder (F90.1), antisocial personality disorder (F60.2), borderline personality disorder (F60.3) or any form of schizophrenia or related psychotic disorder (F20-F29).

Sponsors & Collaborators

• Karolinska Institutet: lead
• Child and Adolescent Psychiatry, Stockholm: collaborator
• Region Stockholm: collaborator
• Stiftelsen Sunnerdahls Handikappfond: collaborator
• The Swedish Research Council: collaborator
• The Pediatric Research Foundation at Astrid Lindgren Children's Hospital: collaborator
• Majblomman: collaborator

Study Sites (1)

Child & Adolescent Psychiatry Research Center, KIND

Stockholm, 11330, Sweden

Location

Related Publications (6)

• Reichow B, Steiner AM, Volkmar F. Social skills groups for people aged 6 to 21 with autism spectrum disorders (ASD). Cochrane Database Syst Rev. 2012 Jul 11;2012(7):CD008511. doi: 10.1002/14651858.CD008511.pub2.

  PMID: 22786515 BACKGROUND

• 2. Bölte S., Choque-Olsson N., Swedish version, KONTAKT, Social färdighetsträning i grupp med fokus på kommunikation och social interaktion vid autismspektrumtillstånd enligt Frankfurtmodellen. Hogrefe, 2011.

  BACKGROUND

• Herbrecht E, Poustka F, Birnkammer S, Duketis E, Schlitt S, Schmotzer G, Bolte S. Pilot evaluation of the Frankfurt Social Skills Training for children and adolescents with autism spectrum disorder. Eur Child Adolesc Psychiatry. 2009 Jun;18(6):327-35. doi: 10.1007/s00787-008-0734-4. Epub 2009 Jan 22.

  PMID: 19165532 BACKGROUND

• Choque Olsson N, Bolte S. Brief report: "Quick and (not so) dirty" assessment of change in autism: cross-cultural reliability of the Developmental Disabilities CGAS and the OSU autism CGI. J Autism Dev Disord. 2014 Jul;44(7):1773-8. doi: 10.1007/s10803-013-2029-y.

  PMID: 24379174 BACKGROUND

• Choque Olsson N, Flygare O, Coco C, Gorling A, Rade A, Chen Q, Lindstedt K, Berggren S, Serlachius E, Jonsson U, Tammimies K, Kjellin L, Bolte S. Social Skills Training for Children and Adolescents With Autism Spectrum Disorder: A Randomized Controlled Trial. J Am Acad Child Adolesc Psychiatry. 2017 Jul;56(7):585-592. doi: 10.1016/j.jaac.2017.05.001. Epub 2017 May 10.

  PMID: 28647010 BACKGROUND

• Choque Olsson N, Rautio D, Asztalos J, Stoetzer U, Bolte S. Social skills group training in high-functioning autism: A qualitative responder study. Autism. 2016 Nov;20(8):995-1010. doi: 10.1177/1362361315621885. Epub 2016 Feb 24.

  PMID: 26912485 DERIVED

Related Links

• Homepage KIND

MeSH Terms

Conditions

Autism Spectrum Disorder; Attention Deficit Disorder with Hyperactivity; Anxiety Disorders; Depression

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders; Attention Deficit and Disruptive Behavior Disorders; Behavioral Symptoms; Behavior

Study Officials

• Sven Bölte, PhD, Professor

  Karolinska Institutet, Center of Neurodevelopmental Disorders (KIND)

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor, PhD, head of pediatric neuropsychiatry unit

Study Record Dates

• First Submitted: April 20, 2013
• First Posted: May 15, 2013
• Study Start: August 1, 2012
• Primary Completion: March 1, 2016
• Study Completion: March 1, 2016
• Last Updated: August 22, 2017

Record last verified: 2017-08

Locations

SE (1)