Effect of Pumpkin Seed Oil on Hair Growth in Men With Androgenetic Alopecia

NCT01852487 | Completed

• 1 other identifier: Pumpkin0912
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Androgenic alopecia is the most common cause of hair loss in men. Finasteride and minoxidil are available in treatment of androgenetic alopecia, although the former causes decreased libido or ejaculate volume, erectile dysfunction, the latter causes scaling, itching of the scalp. Recently, Pulpkin Seed Oil shows some improved clinical efficacy on scalp hair growth in men with androgenetic alopecia, but there is no evidence to support this. The investigators conducted a randomized, double-blind, placebo-controlled efficacy and tolerability trial of Pumpkin seed oil (400mg/day)therapy in male patients with androgenetic alopecia.

Conditions

Androgenic Alopecia

Keywords

Pumpkin seed oil; Hair growth; Men

Outcome Measures

Primary Outcomes (1)

• investigator assessment score using photographs of scalp hair

  at weeks 12 and 24

Secondary Outcomes (1)

• patient self-assessment scores

  at weeks 12 and 24

Other Outcomes (1)

• hair analysis using phototrichogram

  at weeks 12 and 24

Study Arms (2)

Pumpkin Seed Oil

ACTIVE COMPARATOR

400mg/ day during 6 months

Dietary Supplement: 400mg /day during 6 months

sweet potato starch

PLACEBO COMPARATOR

400mg/day during 6months

Interventions

400mg /day during 6 months DIETARY_SUPPLEMENT

Pumpkin Seed Oil

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: male
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• to 65 years of age
• Androgenetic alopecia of Norwood-Hamilton scale grade II-V

You may not qualify if:

• Severe medical problems including renal problems, prostate diseases, diabetes mellitus o
• Patients who took any medicine which can affect the hair growth in recent 3 months.

Sponsors & Collaborators

• Dream Plus: lead

Study Sites (1)

Pusan National University Yangsan Hospital

Yangsan, Gyeongsangnam-do, 626-770, South Korea

Location

MeSH Terms

Conditions

Alopecia; Multiple Endocrine Neoplasia Type 1

Condition Hierarchy (Ancestors)

Hypotrichosis; Hair Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Multiple Endocrine Neoplasia; Endocrine Gland Neoplasms; Neoplasms by Site; Neoplasms; Neoplasms, Multiple Primary; Neoplastic Syndromes, Hereditary; Genetic Diseases, Inborn; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Endocrine System Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: QUADRUPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: May 9, 2013
• First Posted: May 13, 2013
• Study Start: February 1, 2012
• Primary Completion: December 1, 2012
• Study Completion: December 1, 2012
• Last Updated: May 13, 2013

Record last verified: 2013-05

Locations

KR (1)