NCT01849523

Brief Summary

Background Physical as well as psychosocial complaints are frequently present in patients with a neuroendocrine tumor (NET). Adequate information is seen as an essential aspect of supportive care. The aim of the current study is to test the effectiveness of a web-based tailored information and support system targeting patients' information and care needs. Key features of this system are self-screening of physical and psychosocial problems, tailored education on reported problems and self-referral to professional health care. Objective To detect whether a web-based tailored information and support system improves patients' perception and satisfaction of received information. The investigators hypothesize that after having received web-based tailored information and support patients feel more informed and are more satisfied with the received information than when receiving standard care. Study design The present study is a randomized prospective longitudinal experimental multicenter pilot study. In this study, we want to examine the effect sizes on the perception and satisfaction by the patient of received information (primary objective) and secondary objectives after having used web-based tailored information and support. Eligible are newly diagnosed NET-patients (N=40) (diagnosed less than 3 months ago). Patients will be asked to fill out questionnaires at baseline and after 12 weeks, on socio-demographic features (only at baseline), internet use (only at baseline), health care use, patients' perception and satisfaction of received information, distress, quality of life and empowerment (only after 12 weeks). Study population Patients diagnosed with a NET (any type of NET, any phase of disease) who are under treatment at the Department of Medical Oncology in the University Medical Center Groningen or Hospital Medisch Spectrum; twenty will be invited to participate in the study. Intervention During 12 subsequent weeks, a personalized website (with a surname/password) will become available to patients in the experimental group beside the usual standard care. Key features of the website are self-screening, tailored patient education and self-referral. Self-screening will be performed by an online version of the Dutch Distress thermometer (DT) and Problem List (PL). Patients will receive automated feedback on their DT score immediately after test completion together with information regarding problems reported on the PL, options for (self)-help and possibilities for referral to professional care. Contact information will also be available to discuss questions, problems and/or referral needs. Patients may also request a telephone call. Main study endpoint The primary endpoint is to detect an improvement in patients' perception and satisfaction of received information after having received web-based tailored information and support.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2013

Shorter than P25 for not_applicable

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 3, 2013

Completed
5 days until next milestone

First Posted

Study publicly available on registry

May 8, 2013

Completed
5 months until next milestone

Study Start

First participant enrolled

October 1, 2013

Completed
10 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2014

Completed
Last Updated

May 6, 2024

Status Verified

May 1, 2024

Enrollment Period

10 months

First QC Date

May 3, 2013

Last Update Submit

May 3, 2024

Conditions

Keywords

Neuroendocrine tumorWebsiteInformationPsychosocial support

Outcome Measures

Primary Outcomes (1)

  • detect an improvement in perception and satisfaction of the received information

    The primary objective is to detect an improvement in perception and satisfaction of the received information by NET-patients after having used the online tailored information and support system. We hypothesize that patients perceive to have received more information and are more satisfied with the received information after having used the web-based tailored information and support system.

    14 weeks. This is the period a patient can use the website, thereafter a end-of study questionnaire will be filled out

Secondary Outcomes (3)

  • Distress level after receiving information

    14 weeks. This is the period a patient can use the website, thereafter a end-of study questionnaire will be filled out

  • Quality of life

    14 weeks. This is the period a patient can use the website, thereafter a end-of study questionnaire will be filled out

  • Empowerment enhancement

    14 weeks. This is the period a patient can use the website, thereafter a end-of study questionnaire will be filled out

Study Arms (2)

Web-based information and support

EXPERIMENTAL

Web-based tailored information and support

Behavioral: Web-based information and support

Standard care

NO INTERVENTION

Standard care

Interventions

Web-based information and support

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult NET patients (aged ≥ 18 years of age) with any tumor site and disease stage.
  • Ability to comprehend Dutch (both reading and writing).
  • Informed consent provided.

You may not qualify if:

  • Estimated life expectancy less than 3 months.
  • Patients with a second primary tumor for which active follow-up or treatment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Medical Spectrum Twente

Enschede, Netherlands

Location

University Medical Center Groningen

Groningen, 9713 GZ, Netherlands

Location

Related Publications (1)

  • Bouma G, de Hosson LD, van Woerkom CE, van Essen H, de Bock GH, Admiraal JM, Reyners AKL, Walenkamp AME. Web-based information and support for patients with a newly diagnosed neuroendocrine tumor: a feasibility study. Support Care Cancer. 2017 Jul;25(7):2075-2083. doi: 10.1007/s00520-017-3598-7. Epub 2017 Feb 9.

MeSH Terms

Conditions

Neuroendocrine Tumors

Interventions

Palliative Care

Condition Hierarchy (Ancestors)

Neuroectodermal TumorsNeoplasms, Germ Cell and EmbryonalNeoplasms by Histologic TypeNeoplasmsNeoplasms, Nerve Tissue

Intervention Hierarchy (Ancestors)

Patient CareTherapeuticsHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • A.M.E. Walenkamp, MD, PhD

    University Medical Center Groningen

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 3, 2013

First Posted

May 8, 2013

Study Start

October 1, 2013

Primary Completion

August 1, 2014

Study Completion

August 1, 2014

Last Updated

May 6, 2024

Record last verified: 2024-05

Locations