Retinal Detachment - Demographic and Clinical Survey

NCT01845571 | Unknown

• 1 other identifier: 13.12.2011
• Study Type: observational
• Target: 400
• Locations: 1 country
• Sites: 1

Brief Summary

Background: Rhegmatogenous retinal detachment is an ophthalmic emergency that, without surgical repair, often leads to blindness. The incidence is about 1/10000/year. The leading causes are myopia and aging which cause retinal tears often resulting in retinal detachment. Patients commonly experience photopsia, floaters, and peripheral visual field loss. Two different general surgical treatment options exist for retinal detachment; scleral buckling or vitrectomy. However, the precise indications for each approach have not been well established. Correct classification of the retinal detachment is important. The first step is to decide whether an intra- or extra-ocular surgical approach is more appropriate. Simple rhegmatogenous retinal detachments are usually treated extraocularly with scleral buckling surgery, whereas more complicated cases require intraocular primary pars plana vitrectomy and one or more of gas, silicone oil, laser therapy, or cryotherapy. Study objectives: The purpose of this study is to evaluate different surgical techniques for the treatment of retinal detachment. Data relating to retinal status before treatment, surgical treatment, post-operative anatomy and visual acuity, post-operative OCT, and intra- and post-operative complications will be collected. Vitreous cytokines will also be analyzed to monitor intravitreal inflammation as a result of retinal detachment.

Conditions

Rhegmatogenous Retinal Detachment

Outcome Measures

Primary Outcomes (2)

• Vision

  2 years

• Aqueous cytokine Levels

  baseline

Secondary Outcomes (2)

• OCT

  baseline

• Surgical Data

  2 years

Study Arms (1)

Retinal detachment group

400 patients patients, who received surgery due to retinal detachment exclusion: if patients had prior vitrectomy or scleral buckel if patients have no adequate follow-up

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

People will be selected from the surgery database of Ass.Prof.PD.Dr. Stefan Sacu and Prof. Dr. Michael Georgopoulos from the Medical University of Vienna.

You may qualify if:

• Patients who received surgery due to retinal detachment between January 2008 and Decemebr 2012.
• Surgery was performed by either Ass.Prof.PD.Dr. Stefan Sacu or Prof.Dr. Michael Georgopoulos

You may not qualify if:

• If patients had prior vitrectomy or scleral buckel. If patients had no adequate follow-up.

Sponsors & Collaborators

• Medical University of Vienna: lead

Study Sites (1)

Insitute of Ophthalmology and Optometry, Medical University of Vienna

Vienna, 1090, Austria

RECRUITING

Biospecimen

Retention: SAMPLES WITHOUT DNA

vitreous body samples and blood plasmsa for evaluation of cytocines levels.

Study Officials

• Stefan Sacu, Prof

  Medical University of Vienna

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: OTHER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ass.Prof.PD.Dr.

Study Record Dates

• First Submitted: January 11, 2012
• First Posted: May 3, 2013
• Study Start: October 1, 2011
• Primary Completion: December 1, 2023
• Study Completion: December 1, 2023
• Last Updated: March 15, 2023

Record last verified: 2023-03

Locations

AU (1)