Abu Dhabi Diabetes and Obesity Study

NCT01843959 | Completed

• 1 other identifier: IREC008
• Study Type: observational
• Target: 2,130
• Locations: 1 country
• Sites: 1

Brief Summary

A cross-sectional study investigating the aetiology, mechanisms and associated complications contributing to obesity and diabetes within the UAE population. The study will be carried out in two main sample populations; children and adults, and characterized by the occurrence of obesity and diabetes. The main samples will then be divided into a subgroup for metabolomic analysis. Patients will be recruited from the Imperial College London Diabetes Centre. The study is aimed at elucidating the various factors that have an impact or may influence obesity and diabetes in the Emirati population.

Conditions

Obesity; Diabetes

Keywords

adenovirus-36; Emirati population

Outcome Measures

Primary Outcomes (1)

• Percentage of the population in the U.A.E that are positive for adenovirus -36, specifically in children.

  The initial aim of the study is to measure the prevalence of adenovirus 36 in the Emirati population.

  One year

Study Arms (1)

Emirati Population

The individuals enrolled in this study will be divided into children (5-16 years of age) and adults (above 18). The groups will be further divided into BMI categories and glucose tolerance groups. \* Group 1: Underweight (adjusted BMI \<10th percentile) and no diabetes * Group 2: Normal weight (adjusted BMI 10th to 84.9th percentile) and no diabetes * Group 3: Overweight or obese children (adjusted BMI \>= 85th percentile) and no diabetes * Group 4: Normal weight (adjusted BMI 10th to 84.9th percentile) and T1DM * Group 5: Overweight or obese children (adjusted BMI ≥ 85th percentile) and T1DM * Group 6: Normal weight (adjusted BMI 10th to 84.9th percentile) and T2DM * Group 7: Overweight or obese children (adjusted BMI ≥ 85th percentile) and T2DM

Eligibility Criteria

• Age: 5 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients from the Imperial College London Diabetes Centre, Abu Dhabi.

You may qualify if:

• All patients are eligible to participate in the study

You may not qualify if:

• Under 5 years of age

Sponsors & Collaborators

• Imperial College London Diabetes Centre: lead

Study Sites (1)

Imperial College London Diabetes Centre

Abu Dhabi, 48338, United Arab Emirates

Location

Related Publications (2)

• Almgren M, Atkinson R, He J, Hilding A, Hagman E, Wolk A, Thorell A, Marcus C, Naslund E, Ostenson CG, Schalling M, Lavebratt C. Adenovirus-36 is associated with obesity in children and adults in Sweden as determined by rapid ELISA. PLoS One. 2012;7(7):e41652. doi: 10.1371/journal.pone.0041652. Epub 2012 Jul 27.

  PMID: 22848557 BACKGROUND

• Atkinson RL. Adenovirus-36 and obesity. Pediatr Obes. 2012 Apr;7(2):e18-9. doi: 10.1111/j.2047-6310.2011.00043.x. No abstract available.

  PMID: 22434760 BACKGROUND

MeSH Terms

Conditions

Obesity; Diabetes Mellitus

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Glucose Metabolism Disorders; Metabolic Diseases; Endocrine System Diseases

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Consultant Endocrinologist

Study Record Dates

• First Submitted: April 25, 2013
• First Posted: May 1, 2013
• Study Start: March 1, 2013
• Primary Completion: April 1, 2017
• Study Completion: April 1, 2017
• Last Updated: October 13, 2021

Record last verified: 2021-10

Locations

AE (1)