Effect of American Ginseng on Exercise-induced Muscle Soreness
1 other identifier
interventional
10
1 country
1
Brief Summary
Healthy participants will ingest American ginseng daily or a placebo for four weeks prior to engaging in a unaccustomed exercise bout designed to induce mild-moderate muscle soreness. Muscle soreness will be assessed via decrements in muscle strength and with a self-rating of perceived soreness before and several times after the exercise.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for phase_1
Started May 2013
Shorter than P25 for phase_1
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
April 4, 2013
CompletedFirst Posted
Study publicly available on registry
April 9, 2013
CompletedStudy Start
First participant enrolled
May 1, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2013
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2013
CompletedMarch 3, 2016
March 1, 2015
6 months
April 4, 2013
March 1, 2016
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
muscle strength
ginseng \& muscle strength
1 month
Study Arms (2)
Treatment
EXPERIMENTALAmerican Ginseng ingestion
Placeobo
PLACEBO COMPARATORnon-active ingredient
Interventions
Effect of four weeks of daily Ginseng intake (2gm/day) on muscle soreness following downhill running exercise
Eligibility Criteria
You may qualify if:
- Healthy men or women, (women must weigh between 55-65 kg., while men must weigh between 75-85kg).
- Participants must not have engaged in any endurance run training in the past 9 months.
You may not qualify if:
- Injured
- Regular runners
- Pregnant (or with any chance they may become pregnant)
- Breast-feeding
- Diabetics or those taking medication for diabetes
- Insomniacs
- Schizophrenics
- Hyper- or hypotension
- Cancer
- Irregular heartbeats
- Heart disease
- Females with endometriosis or uterine fibroids
- Those who have surgery scheduled during the study or within the two weeks following the completion of the study
- Those taking warfarin or medication for depression.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Western Ontario
London, Ontario, N6A 3K7, Canada
Related Publications (1)
Jung HL, Kwak HE, Kim SS, Kim YC, Lee CD, Byurn HK, Kang HY. Effects of Panax ginseng supplementation on muscle damage and inflammation after uphill treadmill running in humans. Am J Chin Med. 2011;39(3):441-50. doi: 10.1142/S0192415X11008944.
PMID: 21598413BACKGROUND
MeSH Terms
Interventions
Study Officials
- PRINCIPAL INVESTIGATOR
Peter WR Lemon, PhD
Western University, Canada
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Purpose
- PREVENTION
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
April 4, 2013
First Posted
April 9, 2013
Study Start
May 1, 2013
Primary Completion
November 1, 2013
Study Completion
December 1, 2013
Last Updated
March 3, 2016
Record last verified: 2015-03
Data Sharing
- IPD Sharing
- Will not share