Role of Stress CMR in Predicting Adverse Clinical Events in Patients With Known or Suspected IHD
1 other identifier
observational
2,347
1 country
2
Brief Summary
The investigators plan to use retrospective data to assess heart function and structure abnormalities through the use of an approved vasodilating agent for stress cardiac MRI tests. The investigators are interested in how these MRI findings relate to long-term prognosis in people who are at risk for cardiac disease.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jan 2012
Longer than P75 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 30, 2012
CompletedFirst Submitted
Initial submission to the registry
March 27, 2013
CompletedFirst Posted
Study publicly available on registry
April 1, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 30, 2016
CompletedStudy Completion
Last participant's last visit for all outcomes
August 30, 2018
CompletedNovember 6, 2025
November 1, 2025
4 years
March 27, 2013
November 4, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
A composite outcome measure consisting of cardiovascular mortality and nonfatal MI after index CMR.
"Myocardial infarction" will be defined as hospital admission for acute coronary syndrome (defined by positive serum troponin level with documented electrocardiographic changes, clinical syndrome, or need for percutaneous or surgical revascularization).
target follow up of at least 4 years
Secondary Outcomes (1)
A composite outcome measure consisting of cardiovascular mortality, nonfatal MI, hospitalization for unstable angina or congestive heart failure, and late unplanned coronary bypass surgery at at least 6 months after index CMR.
target follow up of at least 4 years
Eligibility Criteria
Patients above the age of 21 who are clinically referred for stress cardiac MRI.
You may qualify if:
- Age \>/= 21 years old
- No contraindications for cardiac MRI (by renal function or metallic hazards)
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (2)
Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
Massachusetts General Hospital
Boston, Massachusetts, 02215, United States
Related Publications (1)
Shah R, Heydari B, Coelho-Filho O, Murthy VL, Abbasi S, Feng JH, Pencina M, Neilan TG, Meadows JL, Francis S, Blankstein R, Steigner M, di Carli M, Jerosch-Herold M, Kwong RY. Stress cardiac magnetic resonance imaging provides effective cardiac risk reclassification in patients with known or suspected stable coronary artery disease. Circulation. 2013 Aug 6;128(6):605-14. doi: 10.1161/CIRCULATIONAHA.113.001430. Epub 2013 Jun 26.
PMID: 23804252DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
March 27, 2013
First Posted
April 1, 2013
Study Start
January 30, 2012
Primary Completion
January 30, 2016
Study Completion
August 30, 2018
Last Updated
November 6, 2025
Record last verified: 2025-11