NCT01815177

Brief Summary

Arthroscopic transosseous fixation of rotator cuff tears has become an alternative to arthroscopic suture anchor. This novel technique that allows surgeons to perform a standardized arthroscopic transosseous (anchor free) repair of rotator cuff tears can improve postoperative pain and reduce the incidence of shoulder stiffness. The aim of the this study is to compare clinical outcomes of two groups of patients: patients that received an arthroscopic transosseous fixation using the ArthroTunneler tunneling device (Tornier Inc, Edina, Minnesota) versus patients that received an arthroscopic rotator cuff repair using suture anchors.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
75

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Mar 2013

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2013

Completed
17 days until next milestone

First Submitted

Initial submission to the registry

March 18, 2013

Completed
2 days until next milestone

First Posted

Study publicly available on registry

March 20, 2013

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2014

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
Last Updated

February 17, 2016

Status Verified

February 1, 2016

Enrollment Period

1.2 years

First QC Date

March 18, 2013

Last Update Submit

February 16, 2016

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain

    Paracetamol/Codeine 500/30 is given to every patient at 08.00 and 20.00 for the first 5 days. The patient is highly recommended to indicate his pain at 19.30 and to write if there is any modification in the assumption of pain killers.

    first 28 days after surgery

Secondary Outcomes (1)

  • Shoulder Stiffness

    Postoperative passive range of motion is measured 2 months after surgery

Study Arms (2)

Arthroscopic transosseous fixation

EXPERIMENTAL

Patients with torn rotator cuff randomized to experimental treatment receive a complete arthroscopic transosseous cuff repair

Device: Arthroscopic transosseous fixation

Repair using suture anchors

OTHER

Patients randomized to this arm receive an arthroscopic rotator cuff repair using suture anchors.

Device: Suture anchors

Interventions

Also known as: ArthroTunneler transosseous tunneling device (Tornier Inc)
Arthroscopic transosseous fixation
Repair using suture anchors

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age \> 18, \<65
  • Rotator cuff tears
  • Patients given written informed consent
  • BMI ≤ 33

You may not qualify if:

  • Age \> 65, \< 18
  • previous surgical intervention
  • Informed consent not accepted
  • Serious comorbidity
  • Diabetes
  • Metabolic Disorders
  • Active infections
  • Muscular Atrophy
  • Biceps Tenodesis

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Policlinico San Donato (istituto di ricovero e cura a carattere scientifico)

San Donato Milanese, Milano, 20097, Italy

Location

Related Publications (6)

  • Garofalo R, Castagna A, Borroni M, Krishnan SG. Arthroscopic transosseous (anchorless) rotator cuff repair. Knee Surg Sports Traumatol Arthrosc. 2012 Jun;20(6):1031-5. doi: 10.1007/s00167-011-1725-4. Epub 2011 Oct 20.

    PMID: 22011882BACKGROUND
  • Voos JE, Barnthouse CD, Scott AR. Arthroscopic rotator cuff repair: techniques in 2012. Clin Sports Med. 2012 Oct;31(4):633-44. doi: 10.1016/j.csm.2012.07.002.

    PMID: 23040550BACKGROUND
  • Longo UG, Franceschi F, Berton A, Maffulli N, Denaro V. Arthroscopic transosseous rotator cuff repair. Med Sport Sci. 2012;57:142-152. doi: 10.1159/000328900. Epub 2011 Oct 4.

    PMID: 21986052BACKGROUND
  • Salata MJ, Sherman SL, Lin EC, Sershon RA, Gupta A, Shewman E, Wang VM, Cole BJ, Romeo AA, Verma NN. Biomechanical evaluation of transosseous rotator cuff repair: do anchors really matter? Am J Sports Med. 2013 Feb;41(2):283-90. doi: 10.1177/0363546512469092. Epub 2012 Dec 13.

    PMID: 23239668BACKGROUND
  • Garrigues GE, Lazarus MD. Arthroscopic bone tunnel augmentation for rotator cuff repair. Orthopedics. 2012 May;35(5):392-7. doi: 10.3928/01477447-20120426-04.

    PMID: 22588393BACKGROUND
  • Randelli P, Stoppani CA, Zaolino C, Menon A, Randelli F, Cabitza P. Advantages of Arthroscopic Rotator Cuff Repair With a Transosseous Suture Technique: A Prospective Randomized Controlled Trial. Am J Sports Med. 2017 Jul;45(9):2000-2009. doi: 10.1177/0363546517695789. Epub 2017 Mar 24.

MeSH Terms

Conditions

Rotator Cuff Injuries

Interventions

Suture Anchors

Condition Hierarchy (Ancestors)

RuptureWounds and InjuriesShoulder InjuriesTendon Injuries

Intervention Hierarchy (Ancestors)

Internal FixatorsProstheses and ImplantsEquipment and SuppliesOrthopedic Fixation DevicesOrthopedic EquipmentSurgical EquipmentSurgical Fixation Devices

Study Officials

  • Pietro Randelli, MD

    IRCCS Policlinico S. Donato

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

March 18, 2013

First Posted

March 20, 2013

Study Start

March 1, 2013

Primary Completion

May 1, 2014

Study Completion

May 1, 2015

Last Updated

February 17, 2016

Record last verified: 2016-02

Data Sharing

IPD Sharing
Will not share

Locations