Drug-Related Problems and Healthcare Utilization Post-Hospital Discharge

NCT01806038 | Completed

• 1 other identifier: Pro00042998
• Study Type: interventional
• Target: 44
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this study is to investigate whether pharmacist provided counseling and medication dispensing at the patient's bedside can provide better outcomes than the current discharge process at Duke University Hospital. This study will be single-site, prospective, randomized, cohort study. Patients who meet the inclusion and exclusion criteria, and provide consent will be included in this study.

Conditions

Drug Related Problems Post Hospital Discharge; Healthcare Utilization; Discharge Medication Counseling

Keywords

Adverse events; Drug interactions; Healthcare utilization; Discharge medication counseling

Outcome Measures

Primary Outcomes (1)

• Drug-related problems (composite of adverse drug reactions, drug interactions, and failure to receive drugs) during the first 30 days post-hospital discharge

  30 days post-hospital discharge

Secondary Outcomes (3)

• Healthcare utilization

  30 days post-hospital discharge

• Hospital readmissions

  30 days post-hospital discharge

• Treatment delays

  Within 24 hours after hospital discharge

Study Arms (2)

RPh Counseling + Outpatient Dispensing

EXPERIMENTAL

On the day of discharge, a pharmacist will perform a chart review and medication reconciliation on all patients' discharge medications (for patients randomized to the intervention arm). Any medication discrepancies will be addressed with the patient's primary care team. At the time of discharge, the patient will receive his/her discharge medications dispensed from the Duke Outpatient Pharmacy, along with medication counseling by a licensed pharmacist.

Other: RPh Counseling + Outpatient Med Dispensing at Discharge

Routine Med Dispensing + Counseling

ACTIVE COMPARATOR

At hospital discharge, patients will receive standard discharge procedures and obtain discharge medications per their usual process

Other: Discharge Med Dispensing Plus Counseling - Current Practice

Interventions

RPh Counseling + Outpatient Med Dispensing at Discharge OTHER

On the day of discharge, a pharmacist will perform a chart review and medication reconciliation on all patients' discharge medications (for patients randomized to the intervention arm). Any medication discrepancies will be addressed with the patient's primary care team. At the time of discharge, the patient will receive his/her discharge medications dispensed from the Duke Outpatient Pharmacy, along with medication counseling by a licensed pharmacist

RPh Counseling + Outpatient Dispensing

Discharge Med Dispensing Plus Counseling - Current Practice OTHER

At hospital discharge, patients will receive standard discharge procedures and obtain discharge medications per their usual process

Routine Med Dispensing + Counseling

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Adult patients age 18 years or older scheduled for discharge to self-care from a Duke University Hospital Adult General Medicine Service that does not have a rounding pharmacist
• Able to be contacted via phone within 30 days post-discharge
• Able to speak and understand English
• (For intervention patients) Have at least one prescription filled by Duke Outpatient Pharmacy and receive medication counseling by a pharmacist at the time of discharge
• Of sufficient physical or mental capacity to provide informed consent, understand the medication counseling, manage their own medications, and answer the telephone questionnaire

You may not qualify if:

• Patients receiving medication-related counseling from other pharmacists (e.g., transplant patients or new start warfarin patients) or other healthcare providers (e.g., diabetes educators) during their hospital stay and/or at time of hospital discharge
• Patients without a telephone for follow up
• Patients with hearing and/or visual impairment
• Patients discharged to police custody
• Patients who are likely to be discharged the same day as admission
• Patients who, in the judgment of the Attending Physician, are not candidates for this study

Sponsors & Collaborators

• Duke University: lead

Study Sites (1)

Duke University Hospital

Durham, North Carolina, 27710, United States

Location

Study Officials

• Paul W. Bush, PharmD, MBA

  Department of Pharmacy, Duke University Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: HEALTH SERVICES RESEARCH
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 5, 2013
• First Posted: March 7, 2013
• Study Start: March 1, 2013
• Primary Completion: April 1, 2014
• Study Completion: May 1, 2014
• Last Updated: November 13, 2014

Record last verified: 2014-04

Locations

US (1)