Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)
RENAL AID
1 other identifier
observational
2,000
1 country
1
Brief Summary
A central goal of this data repository is to collect data from a large population of subjects with a variety of renal disease states. Cohorts will include subjects with diabetes, inflammatory/autoimmune and transplant related renal conditions. Additionally, the repository will have the capacity to store biospecimens and electronic data in control subjects without established renal disease. This initiative will provide an opportunity to compare data from various disease states and controls with the objective of determining clinical and biological factors that predict disease progression, response to therapy and identify discriminating noninvasive clinical and biological features that predict renal biopsy findings.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2013
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2013
CompletedFirst Submitted
Initial submission to the registry
February 15, 2013
CompletedFirst Posted
Study publicly available on registry
March 1, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 1, 2028
ExpectedStudy Completion
Last participant's last visit for all outcomes
August 1, 2028
April 4, 2025
April 1, 2025
15.5 years
February 15, 2013
April 1, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Change in disease progression
Up to 10 years
Study Arms (3)
Native, Renal Tissue Preservation Group
Subjects who have a renal biopsy and the tissue is possessed and maintained by the RENAL AID repository.
Native, Non-tissue Preservation Group
1. Subjects who have had a renal biopsy but the tissue is not held by RENAL AID repository; and/or 2. Subjects with diabetes and renal disease who have not had a renal biopsy.
Transplant Nephropathy Group
Subjects who have had a renal transplant and require a transplant biopsy for either surveillance or "for-cause" indications.
Eligibility Criteria
Subjects will be recruited from The Rogosin Institute, NewYork Presbyterian Hospital and affiliated institutions.
You may qualify if:
- All Groups:
- Males or females
- years of age and older
- Willing and able to provide informed consent
- Native Biopsy Tissue Group:
- \- Require an initial kidney biopsy for medical necessity
- Native Kidney, Non-tissue Group:
- Previously had a kidney biopsy and the tissue is not stored in this biorepository; or
- Have diabetes and kidney disease and have not had a kidney biopsy
- Allograft Tissue Group:
- \- Have undergone a renal transplant and require a transplant biopsy for either surveillance or "for-cause" indications.
You may not qualify if:
- \- Inability to provide informed consent.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- The Rogosin Institutelead
- New York Presbyterian Hospitalcollaborator
- Weill Medical College of Cornell Universitycollaborator
Study Sites (1)
The Rogosin Institute
New York, New York, 10021, United States
Biospecimen
Blood, urine, tissue
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Alan S Perlman, M.D.
The Rogosin Institute
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Target Duration
- 10 Years
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
February 15, 2013
First Posted
March 1, 2013
Study Start
February 1, 2013
Primary Completion (Estimated)
August 1, 2028
Study Completion (Estimated)
August 1, 2028
Last Updated
April 4, 2025
Record last verified: 2025-04