Key Insights

Highlights

Success Rate

75% trial completion

Clinical Risk Assessment

Based on trial outcomes

Low Risk

Score: 29/100

Termination Rate

9.5%

2 terminated out of 21 trials

Success Rate

75.0%

-11.5% vs benchmark

Late-Stage Pipeline

29%

6 trials in Phase 3/4

Results Transparency

50%

3 of 6 completed with results

Key Signals

3 with results75% success

Data Visualizations

Phase Distribution

18Total
Not Applicable (3)
P 1 (1)
P 2 (8)
P 3 (3)
P 4 (3)

Trial Status

Completed6
Unknown6
Recruiting5
Terminated2
Not Yet Recruiting1
Active Not Recruiting1

Trial Success Rate

75.0%

Benchmark: 86.5%

Based on 6 completed trials

Clinical Trials (21)

Showing 20 of 20 trials
NCT06858319Phase 3Recruiting

Open-label Extension Study of Zigakibart in Adults With IgA Nephropathy.

NCT06797518Phase 2RecruitingPrimary

Study to Evaluate the Impact of Iptacopan on Top of SOC on Biopsy Changes in Kidneys of Adult Patients With IgAN

NCT01802034Recruiting

Repository of Novel Analytes Leading to Autoimmune, Inflammatory and Diabetic Nephropathies (RENAL AID)

NCT04663204Phase 2Active Not Recruiting

A Study of the Safety and Activity of Sparsentan for the Treatment of Incident Patients With Immunoglobulin A Nephropathy

NCT05791162Not ApplicableRecruitingPrimary

Interest of Follicular Helper Lymphocytes / Regulatory Follicular Helper Lymphocytes Ratio in IgA Nephropathy

NCT03841448Phase 2Terminated

A Study of Cemdisiran in Adults With Immunoglobulin A Nephropathy (IgAN)

NCT06528015Phase 4Not Yet RecruitingPrimary

Efficacy and Safety of Probiotics Combined With Enteric-coated Budesonide Capsules in Patients With Primary IgA Nephropathy

NCT05510323Phase 3RecruitingPrimary

Efficacy of Immunosuppressive Therapy for IgA Nephropathy With Stage 3 or 4 CKD

NCT05797051UnknownPrimary

Application of Hyperspectral Imaging in the Diagnosis of Glomerular Diseases

NCT04342325Phase 1CompletedPrimary

The Clinical Trial of ADR-001 for IgA Nephropathy

NCT02647255Phase 2TerminatedPrimary

Trial of Plasma Exchange for Severe Crescentic IgA Nephropathy

NCT04020328Phase 4UnknownPrimary

Leflunomide Plus Low Dose Corticosteroid in Immunoglobulin A (IgA) Nephropathy With Renal Insufficiency

NCT04092491UnknownPrimary

Study of the IgA Repertoire During IgA Deposition Nephropathy.

NCT02232776Phase 3CompletedPrimary

Efficacy and Safety of Losartan in Children With Ig A Nephropathy

NCT02160132Phase 2UnknownPrimary

A Controlled Study of Steroids Therapy for Patients of IgA Nephropathy With Active Pathological Changes.

NCT00396721Phase 2CompletedPrimary

Sirolimus Therapy for Poor Prognosis Immunoglobulin A Nephropathy

NCT01184599Phase 4UnknownPrimary

A Prospective Study of the Kidney Protective Effect of Aliskiren in Hypertensive Patients With IgA Nephropathy

NCT00521508Not ApplicableCompletedPrimary

Role of Regulatory T Cells in Pathogenesis of Primary IgA Nephropathy

NCT00446459Phase 2Completed

Effects of Mycophenolate Mofetil (MMF) On Anti-HLA (Human Leukocyte Antigen)Antibody Levels In Patients Awaiting Cadaveric Renal Transplant.

NCT00446251Phase 2Completed

Effects of Rituximab and Mycophenolate Mofetil (MMF) on Highly Sensitized Patients Awaiting Renal Transplant

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