NCT01795105

Brief Summary

This is a Post-Marketing Surveillance study of Abilify® tablets in accordance with Korean regulations on New Drug Re-examination (i.e. New Drug Re-examination Standards: KFDA Notification No. 2010-94 dated 27 December 2010).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
692

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jun 2012

Typical duration for all trials

Geographic Reach
1 country

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2012

Completed
8 months until next milestone

First Submitted

Initial submission to the registry

January 31, 2013

Completed
20 days until next milestone

First Posted

Study publicly available on registry

February 20, 2013

Completed
2.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 29, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 29, 2015

Completed
3.8 years until next milestone

Results Posted

Study results publicly available

April 1, 2019

Completed
Last Updated

April 1, 2019

Status Verified

January 1, 2018

Enrollment Period

3 years

First QC Date

January 31, 2013

Results QC Date

January 14, 2018

Last Update Submit

January 4, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Frequency (n) of Subjects With Adverse Event

    Frequency (n) and Percentage(%) of subjects with Adverse event

    Follow-up at least once from baseline to 6 weeks and at least 12weeks

Secondary Outcomes (1)

  • Mean Change in the TS-CGI(Tourette's Syndrome-Clinical Global Impression-Improvement)

    at least 6, 12 weeks interval from baseline

Study Arms (1)

Aripiprazole (Abilify® Tablets/Abilify® ODT)

Eligibility Criteria

Age6 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

Pediatric patients 6 to 18 years of age with Tourette's Disorder according to the approved product market authorization

You may qualify if:

  • Pediatric patients 6 to 18 years of age with Tourette's Disorder
  • Patients who are prescribed Abilify® treatment as per investigator's medical judgment.
  • Patients who gave written authorization to use their personal and health data
  • Patients starting Abilify® treatment after agreement is in place

You may not qualify if:

  • Patients with known hypersensitivity to Aripiprazole or any excipients of Abilify®
  • Patients who have been treated with Abilify®
  • Patients with rare hereditary problems of galactose intolerance, the lapp lactase deficiency, or glucose-galactose malabsorption
  • Patients with score 0(Not assessed) or 1(Normal, not at all ill) in the TS-CGI-S
  • Patients participating in other clinical trial

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

Inha University Hospital

Incheon, South Korea

Location

Chonbuk National University Hospital

Jeonju, 561-712, South Korea

Location

Seoul National University Hospital

Seoul, 110-744, South Korea

Location

Seoul Medical Center

Seoul, 131-795, South Korea

Location

MeSH Terms

Conditions

Tourette Syndrome

Condition Hierarchy (Ancestors)

Basal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTic DisordersMovement DisordersHeredodegenerative Disorders, Nervous SystemNeurodegenerative DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesNeurodevelopmental DisordersMental Disorders

Results Point of Contact

Title
Jeong, Hyo-Won
Organization
KoreaOtsukaPharma

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
Yes

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 31, 2013

First Posted

February 20, 2013

Study Start

June 1, 2012

Primary Completion

May 29, 2015

Study Completion

May 29, 2015

Last Updated

April 1, 2019

Results First Posted

April 1, 2019

Record last verified: 2018-01

Locations