Dextromethorphan Added on for the Patients With ADHD

NCT01787136 | Unknown

• 1 other identifier: TSGH-C97-87
• Study Type: expanded_access
• Target: N/A
• Locations: 0 countries
• Sites: N/A

Brief Summary

Dextromethorphan added on methylphenidate for the patients with attention deficit hyperactivity disorder

Conditions

Attention Deficit Hyperactivity Disorder

Interventions

Dextromethorphan DRUG

added on therapy

Also known as: regrow

Eligibility Criteria

• Age: 6 Years - 25 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)

You may qualify if:

• Patients aged 6 to 25 who have ADHD symptoms will be recruited. They will be screened for the ADHD symptoms with SNAP 4th version. They then will be referred to a psychiatrist to make a final diagnosis of ADHD by the American Diagnostic Statistical Manual 4th version (DSM-IV).

You may not qualify if:

• Patients not willing to participate in the study after detailed explanation.
• Patients who could not follow the investigator's instructions
• Patients who have severe neurological or mental illness like epileptic disorder, history of stroke, schizophrenia, bipolar disorder, mental retardation or uncontrolled suicide risk.
• Patients who have severe medical illness or surgical conditions like uncontrolled abnormal thyroid function, history of heart attack, uncontrolled hypertension.
• Patients who are taking antidepressants, psychotropic medicines within two months prior to the evaluation for entering our study.
• Patients who are allergic to methylphenidate or dextromethorphan.
• Patients with autoimmune disorders
• Patients with asthma or severe infection disorder currently or in the previous two months to avoid the influence of the level of cytokines.

Sponsors & Collaborators

• Tri-Service General Hospital: lead

Related Publications (1)

• Chuang WC, Yeh CB, Wang SC, Pan PY, Shyu JF, Liu YP, Gau SS, Lu RB. Potential Negative Effects of Dextromethorphan as an Add-On Therapy to Methylphenidate in Children With ADHD. Front Psychiatry. 2019 Jun 26;10:437. doi: 10.3389/fpsyt.2019.00437. eCollection 2019.

  PMID: 31333511 DERIVED

MeSH Terms

Conditions

Attention Deficit Disorder with Hyperactivity

Interventions

Dextromethorphan

Condition Hierarchy (Ancestors)

Attention Deficit and Disruptive Behavior Disorders; Neurodevelopmental Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Morphinans; Opiate Alkaloids; Alkaloids; Heterocyclic Compounds; Heterocyclic Compounds, Bridged-Ring; Heterocyclic Compounds, 4 or More Rings; Heterocyclic Compounds, Fused-Ring; Phenanthrenes; Polycyclic Aromatic Hydrocarbons; Polycyclic Compounds

Study Design

• Study Type: expanded access
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Attending Physician

Study Record Dates

• First Submitted: February 6, 2013
• First Posted: February 8, 2013
• Last Updated: April 29, 2022

Record last verified: 2021-03