NCT01771237

Brief Summary

This exploratory study aims to design and test an HIV prevention intervention for young men who have sex with men (MSM) between the ages of 16-20 as this group comprises the US adolescent population most at-risk for HIV infection through sexual contact. To help develop the content and format of our intervention we will first conduct in-depth interviews with twenty-one 18 to 24 year-old young MSM who acquired HIV through male-to-male sexual contact between ages 16-20 (i.e., the target age of our intended intervention). We will then design a group-based primary intervention for young MSM between ages 16-20, relying on the information we gathered from these interviews, as well as consultation from an advisory board of young MSM and HIV prevention experts. Last, we will use an experimental design to compare our intervention to a control condition. We hypothesize that, relative to a control condition of sexual health education and risk reduction, participants in our intervention will demonstrate lower rates of HIV risk behavior, find participation more feasible, and endorse greater acceptability of our intervention.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
121

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jul 2007

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2007

Completed
3.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2011

Completed
2 years until next milestone

First Submitted

Initial submission to the registry

December 18, 2012

Completed
1 month until next milestone

First Posted

Study publicly available on registry

January 18, 2013

Completed
Last Updated

January 27, 2021

Status Verified

January 1, 2021

Enrollment Period

3.5 years

First QC Date

December 18, 2012

Last Update Submit

January 25, 2021

Conditions

Keywords

HIV infection

Outcome Measures

Primary Outcomes (1)

  • Change in AIDS-risk behavior (AIDS-Risk Behavior Assessment - ARBA)

    The ARBA assesses changes in substance use (i.e, type of drugs, number of times, method), sexual behavior (e.g., frequency of condom use, frequency of sex with high-risk partners, frequency of sex while using drugs or alcohol, number of partners, frequency of vaginal, oral, and anal sex, and age of sexual debut) and lifetime needle use (e.g., any history of tattooing, sharing, and piercing) across three time periods (i.e., 2 weeks preintervention, 6 week postintervention, and 12 week postintervention).

    Baseline, 6- and 12-week

Study Arms (2)

MyPeeps Manualized Group Intervention

EXPERIMENTAL

Highly interactive, HIV prevention skills-based group intervention in 6 sessions. Tailored to YMSM.

Behavioral: MyPeeps Manualized Group Intervention

Standard Sexual Health Education

ACTIVE COMPARATOR

Educational group intervention focused on HIV and STI knowledge using a lecture-based format in 6 sessions. Non-tailored to YMSM.

Behavioral: Standard Sexual Health Education

Interventions

Topics include: HIV/STI transmission, interpersonal communication, stigma management, condom use, substance use and risky sex, HIV-related harm reduction

Also known as: MyPeeps Intervention
MyPeeps Manualized Group Intervention

Topics include: HIV/STI transmission facts, myths regarding HIV transmission, information on effectiveness of condom use

Also known as: Sexual health education-as-usual
Standard Sexual Health Education

Eligibility Criteria

Age16 Years - 20 Years
Sexmale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • able to speak and read English
  • age 16-20
  • biological/cisgender male
  • willing and able to provide assent/consent
  • HIV-negative or of an unknown HIV serostatus
  • sexually active with male partner in past 12 mos.
  • willing to provide locator information

You may not qualify if:

  • unable to provide informed consent due to severe mental or physical illness, or substance intoxication at the time of interview
  • active suicidal ideation at the time of baseline interview

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Ann and Robert H. Lurie Children's Hospital of Chicago

Chicago, Illinois, 60611, United States

Location

Related Publications (1)

  • Hidalgo MA, Kuhns LM, Hotton AL, Johnson AK, Mustanski B, Garofalo R. The MyPEEPS randomized controlled trial: a pilot of preliminary efficacy, feasibility, and acceptability of a group-level, HIV risk reduction intervention for young men who have sex with men. Arch Sex Behav. 2015 Feb;44(2):475-85. doi: 10.1007/s10508-014-0347-6. Epub 2014 Aug 19.

MeSH Terms

Conditions

Homosexuality, MaleSubstance-Related DisordersSexual Dysfunctions, PsychologicalHIV Infections

Condition Hierarchy (Ancestors)

HomosexualitySexualitySexual BehaviorBehaviorChemically-Induced DisordersMental DisordersBlood-Borne InfectionsCommunicable DiseasesInfectionsSexually Transmitted Diseases, ViralSexually Transmitted DiseasesLentivirus InfectionsRetroviridae InfectionsRNA Virus InfectionsVirus DiseasesGenital DiseasesUrogenital DiseasesImmunologic Deficiency SyndromesImmune System Diseases

Study Officials

  • Robert Garofalo, MD, MPH

    Ann & Robert H Lurie Children's Hospital of Chicago

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 18, 2012

First Posted

January 18, 2013

Study Start

July 1, 2007

Primary Completion

January 1, 2011

Study Completion

January 1, 2011

Last Updated

January 27, 2021

Record last verified: 2021-01

Locations