NCT01768325

Brief Summary

The purpose of this study is to evaluate a new EUS-guided biopsy needle (ProCore®) comparing it to conventional EUS-TCB needle (Quick-Core®) in the diagnosis of your suspicious disorder. This study needle (ProCore®) is a new EUS-guided biopsy needle and has been recently approved by the U.S. Food and Drug Administration (FDA) for use.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
85

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2012

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2012

Completed
1 year until next milestone

First Submitted

Initial submission to the registry

January 9, 2013

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 15, 2013

Completed
1.3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2014

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2014

Completed
1.4 years until next milestone

Results Posted

Study results publicly available

December 15, 2015

Completed
Last Updated

March 29, 2017

Status Verified

February 1, 2017

Enrollment Period

2.3 years

First QC Date

January 9, 2013

Results QC Date

July 23, 2015

Last Update Submit

February 28, 2017

Conditions

Keywords

ProCore Needle

Outcome Measures

Primary Outcomes (1)

  • Diagnostic Accuracy.

    36 months

Secondary Outcomes (2)

  • Overall Specimen Length

    36 months

  • Number of Needle Passes

    36 months

Study Arms (2)

EUS-Guided biopsy needle (ProCore)

ACTIVE COMPARATOR

Comparison of ProCore core biopsy needle to QuickCore core biopsy needle.Cook Medical core biopsy needle. * The number of needle passes requiring to acquire adequate specimen * Length of core tissue obtained * Diagnostic contribution of immunohistochemical staining * Rates of complications

Device: EUS-Guided biopsy needle (ProCore)

EUS-TCB needle (Quick-Core)

ACTIVE COMPARATOR

Comparison of core biopsy needles. * The number of needle passes requiring to acquire adequate specimen * Length of core tissue obtained * Diagnostic contribution of immunohistochemical staining * Rates of complications

Device: EUS-TCB needle (QuickCore) standard of care

Interventions

* The number of needle passes requiring to acquire adequate specimen were tallied. * Length of core tissue obtained * Diagnostic contribution of immunohistochemical staining * Rates of complications

Also known as: Comparison of core biopsy needles.
EUS-TCB needle (Quick-Core)

* The number of needle passes requiring to acquire adequate specimen were tallied. * Length of core tissue obtained * Diagnostic contribution of immunohistochemical staining * Rates of complications

Also known as: Comparison of core biopsy needles.
EUS-Guided biopsy needle (ProCore)

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Solid tumors ≥ 2 cm in size.

You may not qualify if:

  • Thrombocytopenia

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Indiana University Hospital

Indianapolis, Indiana, 46202-5121, United States

Location

Results Point of Contact

Title
John DeWitt, MD
Organization
Indiana University School of Medicine

Study Officials

  • John M. DeWitt, M.D.

    Indiana University 550 N. University Hospital UH 4100 Indianapolis, IN 46202-5121

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 9, 2013

First Posted

January 15, 2013

Study Start

January 1, 2012

Primary Completion

May 1, 2014

Study Completion

August 1, 2014

Last Updated

March 29, 2017

Results First Posted

December 15, 2015

Record last verified: 2017-02

Data Sharing

IPD Sharing
Will not share

Locations