Longterm Follow-up After Remote Ischemic Preconditioning for Prevention of Contrast-induced Nephropathy
RenProLong
Remote Preconditioning for Contrast-Induced Acute Kidney Injury: Long-Term Follow up (RenPro Longterm)
1 other identifier
observational
81
1 country
1
Brief Summary
Remote ischemic preconditioning reduces the incidence of contrast-induced acute kidney injury in patients undergoing elective coronary angiography. This study was designed to acquire long-term data of initially randomized patients in the RenPro Trial.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jul 2012
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
July 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2012
CompletedFirst Submitted
Initial submission to the registry
December 28, 2012
CompletedStudy Completion
Last participant's last visit for all outcomes
January 1, 2013
CompletedFirst Posted
Study publicly available on registry
January 3, 2013
CompletedJanuary 3, 2013
December 1, 2012
5 months
December 28, 2012
December 28, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
MACCE
Major Adverse Cardiac and Cerebrovascular Events (Combined primary endpoint): All-cause mortality, cardiovascular mortality, rehospitalization, stroke, myocardial infarction, hemodialysis
1 Year
Secondary Outcomes (1)
Renal function
1 year
Study Arms (1)
Subjects with impaired renal function
Subjects with baseline impaired renal function undergoing cardiac catheterization with contrast-medium exposure
Interventions
Subjects received ischemic preconditioning previous to cardiac catheterization
Eligibility Criteria
Patients refered for elective cardiac catherization to the university hospital of Cologne. All patients who participated to the RenPro trial (www.germanctr.de; DRKS-ID DRKS00000666)
Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.
Sponsors & Collaborators
Study Sites (1)
University of Cologne
Cologne, North Rhine-Westphalia, 50937, Germany
Related Publications (1)
Er F, Nia AM, Dopp H, Hellmich M, Dahlem KM, Caglayan E, Kubacki T, Benzing T, Erdmann E, Burst V, Gassanov N. Ischemic preconditioning for prevention of contrast medium-induced nephropathy: randomized pilot RenPro Trial (Renal Protection Trial). Circulation. 2012 Jul 17;126(3):296-303. doi: 10.1161/CIRCULATIONAHA.112.096370. Epub 2012 Jun 26.
PMID: 22735306RESULT
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Fikret Er, MD
University Hospital of Cologne
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
December 28, 2012
First Posted
January 3, 2013
Study Start
July 1, 2012
Primary Completion
December 1, 2012
Study Completion
January 1, 2013
Last Updated
January 3, 2013
Record last verified: 2012-12