NCT01746537

Brief Summary

A prospective, observational, case series investigating the feasibility of utilizing OCT scans of the anterior chamber of eyes with uveitis.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,500

participants targeted

Target at P75+ for all trials

Timeline
37mo left

Started Jun 2012

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress82%
Jun 2012Jun 2029

Study Start

First participant enrolled

June 1, 2012

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

December 7, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

December 11, 2012

Completed
15.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2028

Expected
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2029

Last Updated

March 4, 2026

Status Verified

March 1, 2026

Enrollment Period

16 years

First QC Date

December 7, 2012

Last Update Submit

March 2, 2026

Conditions

Uveitis

Outcome Measures

Primary Outcomes (1)

  • Use the OCT to objectively image and grade the degree of anterior chamber inflammation in eyes with inactive and active uveitis.

    one year

Eligibility Criteria

Sexall
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Patients with inactive and active uveitis.

You may qualify if:

  • All patients presenting to Cole Eye Institute with uveitis.

You may not qualify if:

  • Inability to provide informed consent, including non-English speaking and cognitively/mentally impaired.
  • Severe corneal opacities preventing imaging of anterior chamber

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cole Eye Institute

Cleveland, Ohio, 44195, United States

RECRUITING

MeSH Terms

Conditions

Uveitis

Condition Hierarchy (Ancestors)

Uveal DiseasesEye Diseases

Study Officials

  • Sunil K Srivastva, MD

    The Cleveland Clinic

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Sunil K Srivastava, M.D.

CONTACT

216-636-2286

Kimberly M Baynes, BSN, RN

CONTACT

216-44-2566

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Medical Doctor

Study Record Dates

First Submitted

December 7, 2012

First Posted

December 11, 2012

Study Start

June 1, 2012

Primary Completion (Estimated)

June 1, 2028

Study Completion (Estimated)

June 1, 2029

Last Updated

March 4, 2026

Record last verified: 2026-03

Locations

US(1)