NCT01735981

Brief Summary

To examine the benefits of using a video-game, Dance, Dance, Revolution, as an exercise modality to improve gait and balance in individuals with Huntington's disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
24

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2008

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2008

Completed
2.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 1, 2010

Completed
1.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2012

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

November 7, 2012

Completed
21 days until next milestone

First Posted

Study publicly available on registry

November 28, 2012

Completed
8.7 years until next milestone

Results Posted

Study results publicly available

August 9, 2021

Completed
Last Updated

August 9, 2021

Status Verified

July 1, 2021

Enrollment Period

2.4 years

First QC Date

November 7, 2012

Results QC Date

March 16, 2021

Last Update Submit

July 15, 2021

Conditions

Huntington's Disease

Keywords

Huntington's Diseasegaitexercisebalancevideo game

Outcome Measures

Primary Outcomes (11)

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: forward velocity.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: forward stride length.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: forward swing percent.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: forward double support percent.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: forward heel to heel base of support.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: backwards velocity.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: backwards stride length.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: backwards swing percent.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: backwards double support percent.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: backwards heel to heel base of support.

    6 weeks

  • Gait Parameters

    utilized GAITRite to obtain spatiotemporal measures of gait: obstacle velocity.

    6 weeks

Secondary Outcomes (4)

  • Tinetti Mobility Test

    6 weeks

  • Four Square Step Test

    6 weeks

  • Activities-Specific Balance Confidence Scale

    6 weeks

  • World Health Organization Quality of Life

    post intervention and post hand-held game, each lasts 6 weeks

Study Arms (2)

video game exercise

EXPERIMENTAL

Video game exercise using Dance Dance Revolution

Other: Video game exercise using Dance Dance RevolutionOther: hand-held video game

control

OTHER

hand-held video game control

Other: Video game exercise using Dance Dance RevolutionOther: hand-held video game

Interventions

Video game exercise using Dance Dance RevolutionOTHER

use of the video-game, Dance, Dance Revolution as an exercise to improve gait and balance

Also known as: exercise, video-game based exercise
controlvideo game exercise
hand-held video gameOTHER

hand-held video games

controlvideo game exercise

Eligibility Criteria

Age18 Years - 79 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • adults 18 - 79 with a diagnosis of Huntington's disease

You may not qualify if:

  • cannot walk 10 feet without assistance, any other neurologic condition

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Ohio State University Atwell Hall

Columbus, Ohio, 43210, United States

Location

MeSH Terms

Conditions

Huntington DiseaseMotor Activity

Interventions

Exercise

Condition Hierarchy (Ancestors)

Basal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesDementiaChoreaDyskinesiasMovement DisordersHeredodegenerative Disorders, Nervous SystemNeurodegenerative DiseasesGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesCognition DisordersNeurocognitive DisordersMental DisordersBehavior

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Results Point of Contact

Title
Anne Kloos
Organization
The Ohio State University
kloos.4@osu.edu
614-688-5942

Study Officials

  • Deb Kegelmeyer, DPT, MS

    Ohio State University

    PRINCIPAL INVESTIGATOR

  • Anne Kloos, PT, PhD

    Ohio State University

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
CROSSOVER
Model Details: Participants completed one arm of the study and then crossed over into the other arm of the study
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Associate Professor Clinical Health and Rehabilitation Sciences

Study Record Dates

First Submitted

November 7, 2012

First Posted

November 28, 2012

Study Start

June 1, 2008

Primary Completion

November 1, 2010

Study Completion

June 1, 2012

Last Updated

August 9, 2021

Results First Posted

August 9, 2021

Record last verified: 2021-07

Locations

US(1)