NCT01734668

Brief Summary

The objective of this study is to demonstrate the clinical performance of the Sofia RSV FIA with specimens from symptomatic pediatric subjects who are less than nineteen (19) years of age.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
2,468

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Mar 2012

Shorter than P25 for all trials

Geographic Reach
1 country

17 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2012

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

November 20, 2012

Completed
8 days until next milestone

First Posted

Study publicly available on registry

November 28, 2012

Completed
1 month until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2013

Completed
Last Updated

February 7, 2013

Status Verified

February 1, 2013

Enrollment Period

10 months

First QC Date

November 20, 2012

Last Update Submit

February 5, 2013

Conditions

Outcome Measures

Primary Outcomes (1)

  • High level of sensitivity and specificity for performance vs. culture

    Clinical performance will be based on comparison of the Sofia RSV FIA results to cell culture.

    Culture results within 48 hours of plating

Interventions

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodProbability Sample
Study Population

Recruitment of RSV symptomatic pediatric subjects who are less than nineteen (19) years of age.

You may qualify if:

  • Male or Female
  • Children less than nineteen (19) years of age can participate (assuming appropriate consent is obtained).
  • Must currently be exhibiting symptoms characteristic of respiratory syncytial virus (RSV) illness.
  • Subjects must present with one or more of the following to be eligible for enrollment:
  • Fever, ≥ 37.8º C (100º F) at present or within past 24 hours
  • Moderate to severe runny nose\*
  • Moderate to severe congestion\*
  • Decreased appetite
  • Coughing
  • Sneezing\*
  • Wheezing
  • Irritability
  • Decreased activity
  • Labored breathing

You may not qualify if:

  • Subjects nineteen years of age or older.
  • The parent or legal guardian is unable to understand and consent to participation.
  • Current or prior treatment during this infection with anti-RSV Synagis®.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (17)

Best Medical Group

Phoenix, Arizona, 85042, United States

Location

Santo Nino Medical Clinic

Panorama City, California, 91402, United States

Location

Genesis Community Health

Boynton Beach, Florida, 33435, United States

Location

Gentle Medical Associates

Boynton Beach, Florida, 33435, United States

Location

Pediatrics by the Sea

Delray Beach, Florida, 33483, United States

Location

Soma Pediatrics

Lake Worth, Florida, 33460, United States

Location

Adriana Castro

Miami, Florida, 33173, United States

Location

Lanza Pediatrics

Pensacola, Florida, 32504, United States

Location

Northeast Pediatrics

St. Petersburg, Florida, 33702, United States

Location

St. Petersburg Pediatrics

St. Petersburg, Florida, 33710, United States

Location

Teena Hughes, MD

Tampa, Florida, 33613, United States

Location

Soma Medical Center, PA Pediatric Site #3

West Palm Beach, Florida, 33406, United States

Location

Juan E. Batista, MD PA, Pediatric Site #2

West Palm Beach, Florida, 33415, United States

Location

FastER Urgent Care

Morris Plains, New Jersey, 07950, United States

Location

Twelve Corners Pediatrics

Rochester, New York, 14618, United States

Location

Veritas, PA

Belton, Texas, 76513, United States

Location

Advanced Pediatrics

Vienna, Virginia, 22180, United States

Location

MeSH Terms

Interventions

Diagnosis

Study Officials

  • John D Tamerius, PhD

    Quidel Corporation

    STUDY DIRECTOR

Study Design

Study Type
observational
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 20, 2012

First Posted

November 28, 2012

Study Start

March 1, 2012

Primary Completion

January 1, 2013

Study Completion

January 1, 2013

Last Updated

February 7, 2013

Record last verified: 2013-02

Locations