Fracture and Fall Prevention in Elderly With Osteoporosis

NCT01733303 | Unknown

• 1 other identifier: 201003065R
• Study Type: interventional
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that can cause fracture, injury or mortality. Identifying the factors related to falls occurring within this population is essential for the development of effective regimes for fall prevention. Studies have shown that muscle quality and good posture alignments are critical for balance control in older adults. People are diagnosed with osteoporosis often combining with muscles weakness, and increased spine kyphosis leading vertebral, fractures and poor balance control, even falls. Therefore, improving muscle quality, strengthening weak muscles and correcting postural alignment are essential elements for fracture and fall prevention in older adults with osteoporosis. The long-term objectives of this work are to prevent fracture and fall in older adults with osteoporosis by improving the function of degenerative muscles using exercise training.

Conditions

Osteoporosis

Outcome Measures

Primary Outcomes (3)

• Changes of torque demand to capacity ratio 6 months

  Change from Baseline intorque demand to capacity ratio at 6 months

• Changes of torque demand to capacity ratio at 3 months

  Change from Baseline in torque demand to capacity ratio at 3 months

• Change of torque demand to capacity ratio at 12months

  Change from Baseline in torque demand to capacity ratio at 12 months

Study Arms (1)

Exercise

EXPERIMENTAL

Participants are allocated to the exercise group will commence the personalized core training exercise with EMG biofeedback based on their testing results in muscle quality.

Behavioral: personalized core muscle training program

Interventions

personalized core muscle training program BEHAVIORAL

Participants are allocated to the exercise group will commence the personalized core training exercise with EMG biofeedback based on their testing results in muscle quality. The program will run for 3 months with patients attending for one hour three times a week. The age-matched control group will maintain their usual daily life activities without any specific instruction. The exercise training will be run by an experienced physiotherapist, who will encourage patients individually to progress at their own pace.

Exercise

Eligibility Criteria

• Age: 50 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• able to stand and walk for 5 minutes independently;
• having normal or corrected to normal vision;
• having age between \> 50 years
• with osteopenia (-2.5 \< t-score \< -1.0) or osteoporosis (t-score \<-2.5).

You may not qualify if:

• being pregnant;
• sensory-motor deficits;
• inability of communication
• lack of access to a telephone.
• able to stand and walk for 5 minutes independently;
• having normal or corrected to normal vision;
• having age between \> 50 years
• without osteopenia or osteoporosis (t-score \> -1.0).
• being pregnant;
• sensory-motor deficits;
• inability of communication
• lack of access to a telephone.

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

Physical Therapy Center or the Orthopedic Center in the National Taiwan University Hospital

Taipei, Taiwan, 10055, Taiwan

RECRUITING

MeSH Terms

Conditions

Osteoporosis

Condition Hierarchy (Ancestors)

Bone Diseases, Metabolic; Bone Diseases; Musculoskeletal Diseases; Metabolic Diseases; Nutritional and Metabolic Diseases

Study Officials

• Weili Hsu, PhD

  National Taiwan University Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Weili Hsu, PhD

CONTACT

886-2-3366-8127; wlhsu@ntu.edu.tw

Study Design

• Study Type: interventional
• Phase: not applicable
• Masking: TRIPLE
• Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 5, 2012
• First Posted: November 27, 2012
• Study Start: January 1, 2010
• Primary Completion: December 1, 2015
• Study Completion: December 1, 2015
• Last Updated: November 27, 2012

Record last verified: 2012-11

Locations

TW (1)