NCT01719120

Brief Summary

The aim of this study is to develop an Internet-based self-help therapy program for insomnia in Chinese language, and to conduct a randomized waiting-list controlled trial on the efficacy of Internet-based self-help therapy for insomnia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
312

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2012

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2012

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

October 29, 2012

Completed
3 days until next milestone

First Posted

Study publicly available on registry

November 1, 2012

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2014

Completed
1.1 years until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2015

Completed
Last Updated

May 13, 2016

Status Verified

May 1, 2016

Enrollment Period

1.7 years

First QC Date

October 29, 2012

Last Update Submit

May 12, 2016

Conditions

Keywords

InsomniaCognitive-Behavioral TherapyInternet-BasedSelf-HelpRandomized Controlled Trial

Outcome Measures

Primary Outcomes (1)

  • Sleep parameters (sleep onset latency, sleep efficiency, total sleep time, times of wakening during sleep) changes from baseline to 5-week posttreatment by subjective measures using sleep log.

    12-week posttreatment is only for within-group comparison in treatment groups

    Baseline, 1-week, 5-week, and 12-week posttreatment.

Secondary Outcomes (10)

  • Self-rated sleep quality score measured by the Pittsburgh Sleep Quality Index (PSQI) questionnaire

    Baseline, 1-week, 5-week, and 12-week posttreatment.

  • Self-rated sleep-related cognition score measured by Dysfunctional Beliefs and Attitudes about Sleep Scale (DBAS)

    Baseline, 1-week, 5-week, and 12-week posttreatment.

  • Self-rated severity of depressive and anxiety symptoms measured by Hospital Anxiety and Depression Scale (HADS)

    Baseline, 1-week, 5-week, and 12-week posttreatment

  • Subjects' general health and quality of life regarding physical functioning, social functioning, physical role limitations, emotional role limitations, mental health, vitality, bodily pain, and general health perception measured by Short form -36 (SF-36)

    Baseline, 1-week, 5-week, and 12-week posttreatment.

  • Self-rated fatigue score measured by Multidimensional Fatigue Inventory (MFI)

    Baseline, 1-week, 5-week, and 12-week posttreatment.

  • +5 more secondary outcomes

Study Arms (3)

Self-help CBT with tel. consultation

EXPERIMENTAL

Self-help CBT with tel. consultation (SHTC)group will receive telephone consultation provided by the investigator in addition to self-help cognitive-behavioral therapy once per week for 6 consecutive weeks.During the consultation, the investigator will answer questions about the treatment content, monitor whether the subjects read the assigned materials and comply with the tasks and procedures, and provide encouragement and support.

Behavioral: Cognitive-Behavioral Therapy

Self-help CBT

EXPERIMENTAL

The subjects will receive self-help cognitive-behavioral therapy (SH)once per week for 6 consecutive weeks.

Behavioral: Cognitive-Behavioral Therapy

Waiting-list control (WL)

NO INTERVENTION

Subjects in this group will not receive any kind of treatment during the waiting period. They will receive the treatment identical to the self-help group within 3 months from the baseline.

Interventions

CBT for insomnia aims at changing dysfunctional cognitive beliefs and maladaptive behaviors contributed to the maintenance of insomnia. It involves 4 main components including behavioral, cognitive, educational, and relaxation treatments.

Self-help CBTSelf-help CBT with tel. consultation

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Hong Kong residents aged ≥18 years
  • Predominant complaint of difficulty initiating or maintaining sleep or early morning awakening or nonrestorative sleep with associated distress or impairment in social, occupational and other important areas of functioning for at least 3 nights per week for at least 3 months based on self- administered questionnaire
  • Able to read Chinese and type Chinese or English
  • Have Internet access (PC/ mobile phone), and with an email address
  • Willing to give informed consent and comply with the trial protocol

You may not qualify if:

  • Have suicidal ideas based on self-report

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

the University of Hong Kong

Hong Kong, Hong Kong

Location

Related Publications (1)

  • Ho FY, Chung KF, Yeung WF, Ng TH, Cheng SK. Weekly brief phone support in self-help cognitive behavioral therapy for insomnia disorder: Relevance to adherence and efficacy. Behav Res Ther. 2014 Dec;63:147-56. doi: 10.1016/j.brat.2014.10.002. Epub 2014 Oct 23.

MeSH Terms

Conditions

Sleep Initiation and Maintenance Disorders

Interventions

Cognitive Behavioral Therapy

Condition Hierarchy (Ancestors)

Sleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Intervention Hierarchy (Ancestors)

Behavior TherapyPsychotherapyBehavioral Disciplines and Activities

Study Officials

  • Ka-Fai Chung, MBBS

    The University of Hong Kong

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 29, 2012

First Posted

November 1, 2012

Study Start

August 1, 2012

Primary Completion

April 1, 2014

Study Completion

May 1, 2015

Last Updated

May 13, 2016

Record last verified: 2016-05

Locations