The MURDOCK Study Registry and Biorepository Horizon 1.5

NCT01708408 | Active Not Recruiting DMC

• 1 other identifier: Pro00011196
• Study Type: observational
• Target: 50,000
• Locations: 1 country
• Sites: 1

Brief Summary

The MURDOCK Study Community Registry and Biorepository (Horizon 1.5) aims to create a large-scale community registry and biorepository that can be used as a vehicle for future health services, epidemiologic, clinical trials and other omics-related research.

Conditions

Chronic Disease; Healthy Volunteers

Keywords

biorepository; biobank; registry; community; biospecimens; volunteers; chronic disease; longitudinal; blood; electronic health records; follow-up

Outcome Measures

Primary Outcomes (1)

• The MURDOCK Study Registry and Biorepository Horizon 1.5

  To provide information for large-scale epidemiologic and clinical translational research and the research infrastructure to identify specific phenotypes and outcomes to improve medicine

  Upto 119 months

Study Arms (1)

community

Genetic: Biomarker studies

Interventions

Biomarker studies GENETIC

community

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The Community Registry and Biorepository is designed to create a community registry and biorepository populated by approximately 50,000 residents of Cabarrus County and/or the city of Kannapolis in North Carolina.

You may qualify if:

• A resident of Cabarrus County and/or the city of Kannapolis (and surrounding regions) for 6 or more months of the year
• At least 18 years of age
• Able to understand and give written informed consent, or have a legal guardian or caregiver present to give informed consent by proxy (assent from a participant between ages 12-18 will be obtained when their parent or legal guardian consents on their behalf).
• Willing and able to participate in all 5 components of the registry and biorepository as described above in Section III

Sponsors & Collaborators

• Duke University: lead

Study Sites (1)

Duke Clinical Translational Science Institute-MURDOCK Study

Kannapolis, North Carolina, 28081, United States

Location

Related Publications (1)

• Tenenbaum JD, Christian V, Cornish MA, Dolor RJ, Dunham AA, Ginsburg GS, Kraus VB, McHutchison JG, Nahm ML, Newby LK, Svetkey LP, Udayakumar K, Califf RM. The MURDOCK Study: a long-term initiative for disease reclassification through advanced biomarker discovery and integration with electronic health records. Am J Transl Res. 2012;4(3):291-301. Epub 2012 Jul 23.

  PMID: 22937207 BACKGROUND

Related Links

• MURDOCK Study website

Biospecimen

Retention: SAMPLES WITH DNA

Blood, 25 mL (whole blood, plasma, serum, buffy coat, PAXgene); Urine, 36 mL

MeSH Terms

Conditions

Chronic Disease

Condition Hierarchy (Ancestors)

Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Kristin M Newby, MD

  Duke University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 15, 2012
• First Posted: October 17, 2012
• Study Start: February 1, 2009
• Primary Completion (Estimated): December 1, 2026
• Study Completion (Estimated): December 1, 2026
• Last Updated: February 4, 2026

Record last verified: 2026-02

Locations

US (1)