NCT01699802

Brief Summary

The purpose is to investigate how the adsorptive capacity of the active carbon filter to carbon dioxide in an anaesthetic gas reflector (AnaConDa) is affected by adding inhaled anaesthetic agent. The hypothesis is that addition of inhaled anaesthetic agent will affect the amount of adsorption of carbon dioxide to the active carbon and thereby affect rebreathing of carbon dioxide.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
12

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2012

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

September 1, 2012

Completed
24 days until next milestone

First Submitted

Initial submission to the registry

September 25, 2012

Completed
9 days until next milestone

First Posted

Study publicly available on registry

October 4, 2012

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2014

Completed
Last Updated

May 14, 2015

Status Verified

May 1, 2015

Enrollment Period

2.2 years

First QC Date

September 25, 2012

Last Update Submit

May 13, 2015

Conditions

Ischemic Heart Disease

Outcome Measures

Primary Outcomes (1)

  • Volume of carbon dioxide rebreathing from an anesthetic gas reflector

    Tidal carbon dioxide volume rebreathed from an anesthetic gas reflector correlated to concentration of delivered anesthetic gas.

    2 hours

Secondary Outcomes (1)

  • Quantification of ventilatory requirements to maintain isocapnia with the use of an anesthetic gas reflector.

    2 hours

Study Arms (1)

Inhaled anaesthetic agent

EXPERIMENTAL

The group where the investigators adds inhaled anaesthetic agent when using the anaesthetic gas reflector (AnaConda).

Other: Inhaled anaesthetic agent

Interventions

Inhaled anaesthetic agentOTHER
Inhaled anaesthetic agent

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • elective coronary artery by-pass graft surgery
  • elective valve replacement surgery
  • normal left ventricular ejection fraction on preoperative echocardiography

You may not qualify if:

  • obstructive lung disease
  • restrictive lung disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Skane University Hospital Lund, Cardiothoracic Intensive Care

Lund, SE-221 85, Sweden

Location

MeSH Terms

Conditions

Myocardial Ischemia

Condition Hierarchy (Ancestors)

Heart DiseasesCardiovascular DiseasesVascular Diseases

Study Officials

  • Mikael Bodelsson, Professor

    Divison of Surgery, Department of Anaesthesia, Skane University Hospital, Lund, Sweden

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 25, 2012

First Posted

October 4, 2012

Study Start

September 1, 2012

Primary Completion

December 1, 2014

Study Completion

December 1, 2014

Last Updated

May 14, 2015

Record last verified: 2015-05

Locations

SE(1)