Effect of Subcision and Suction on Acne Scars
Pilot Split Face Randomized, Evaluator Blinded Study on the Effect of Subcision and Suctioning With a Microdermabrasion Device on Rolling Acne Scars
1 other identifier
interventional
20
1 country
1
Brief Summary
The primary objective of this study is to determine whether the use of standard treatment in conjunction with suction will improve acne scars compared to a standard treatment alone.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Sep 2012
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 1, 2012
CompletedFirst Submitted
Initial submission to the registry
September 14, 2012
CompletedFirst Posted
Study publicly available on registry
October 1, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2025
CompletedJanuary 31, 2025
January 1, 2025
13.3 years
September 14, 2012
January 29, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Change in acne scarring compared to baseline after treatments
The change in acne scarring is measured using a global scarring grading system to compare baseline scarring to the treatments.
Baseline and 4 months
Study Arms (2)
Subcision & Suction
EXPERIMENTALStandard treatment for acne scars followed by suction.
Subcision
ACTIVE COMPARATORStandard treatment for acne scars only
Interventions
Eligibility Criteria
You may qualify if:
- Age 18 and over
- Have bilateral rolling acne scars
- Are in good health
- Subject has the willingness and ability to understand and provide informed consent for the use of their tissue and communicate with the investigator.
You may not qualify if:
- Under 18 years of age
- Pregnancy or lactation
- Unable to understand the protocol or give informed consent
- Has mental illness
- Recent Accutane use in the past 6 months
- Prone to hypertrophic and keloidal scarring
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Northwestern University Feinberg School of Medicine, Department of Dermatology
Chicago, Illinois, 60611, United States
Related Publications (1)
Shi VJ, Ma MS, Koza E, Haq M, Ahmed A, Yi MD, Dirr MA, Anvery N, Christensen RE, Pagdhal K, Geisler A, Nodzenski M, Roongpisuthipong W, Brieva JC, Cahn BA, Yoo SS, Lucas J, Poon E, West DP, Fife D, Alam M. Subcision with and without suction for acne scars: a split-faced, rater-blinded randomized control trial. Arch Dermatol Res. 2024 Jun 7;316(7):344. doi: 10.1007/s00403-024-03128-4.
PMID: 38847979DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Murad Alam, MD
Northwestern University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor in Dermatology, Otolaryngology- Head and Neck Surgery, and Surgery-Organ Transplantation
Study Record Dates
First Submitted
September 14, 2012
First Posted
October 1, 2012
Study Start
September 1, 2012
Primary Completion
December 1, 2025
Study Completion
December 1, 2025
Last Updated
January 31, 2025
Record last verified: 2025-01