NCT01693926

Brief Summary

The objective of the study is to evaluate the impact of physical activity in obese and nonobese prepubertal children on:

  1. 1.biological stress responses during a psychosocial stress test
  2. 2.snacking and feeling of hunger in response to the same psychosocial stress test
  3. 3.the moderating factor of attachment on the biological stress responses and on snacking

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
50

participants targeted

Target at P25-P50 for not_applicable obesity

Timeline
Completed

Started Sep 2012

Longer than P75 for not_applicable obesity

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

August 29, 2012

Completed
3 days until next milestone

Study Start

First participant enrolled

September 1, 2012

Completed
25 days until next milestone

First Posted

Study publicly available on registry

September 26, 2012

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2013

Completed
4.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2017

Completed
Last Updated

March 25, 2020

Status Verified

March 1, 2020

Enrollment Period

9 months

First QC Date

August 29, 2012

Last Update Submit

March 23, 2020

Conditions

Keywords

ObesityChildrenPhysical activityStressSnacking

Outcome Measures

Primary Outcomes (3)

  • Change in salivary Cortisol and maximal levels of salivary cortisol in response to the TSST stress test over 2 hours

    9 months

  • Snacking (Caloric intake, corrected for energy expenditure)

    Measure of caloric intake and measure of choice of high-caloric vs low-caloric food snacking after the TSST stress test

    9 months

  • Moderator effect of attachment (4 different attachment categories), i.e. children with a secure attachment will have lower rises in cortisol compared with children in the other 3 attachment categories

    Cortisol levels after the TSST stress test will be lower in children with secure attachment compared to detached, disorganized or preoccupied children (i.e. the 3 other attachment categories).

    9 months

Secondary Outcomes (4)

  • Moderator effect of obesity (WHO criteria)

    9 months

  • Cardiovascular reactivity (changes and maximal levels of blood pressure, heart rate)

    9 months

  • Perceived stress (stress scale from 1-7)

    9 months

  • Moderator role of serious life events and parental worries

    9 months

Study Arms (2)

Acute physical activity intervention

EXPERIMENTAL

25 min of moderate physical activity

Behavioral: Acute physical activity intervention

Placebo

PLACEBO COMPARATOR

25 min of reading (instead of physical activity)

Behavioral: placebo

Interventions

25 min of physical activity. The placebo arm will have 25 min of reading.

Acute physical activity intervention
placeboBEHAVIORAL
Placebo

Eligibility Criteria

Age7 Years - 10 Years
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)

You may qualify if:

  • year old children

You may not qualify if:

  • Severe illness
  • Medications interfering with study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Univeristy of Lausanne, SUPEA

Lausanne, Canton of Vaud, 1011, Switzerland

Location

Related Publications (1)

  • Horsch A, Wobmann M, Kriemler S, Munsch S, Borloz S, Balz A, Marques-Vidal P, Borghini A, Puder JJ. Impact of physical activity on energy balance, food intake and choice in normal weight and obese children in the setting of acute social stress: a randomized controlled trial. BMC Pediatr. 2015 Feb 19;15:12. doi: 10.1186/s12887-015-0326-7.

MeSH Terms

Conditions

ObesityMotor Activity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsBehavior

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Medin adjoint

Study Record Dates

First Submitted

August 29, 2012

First Posted

September 26, 2012

Study Start

September 1, 2012

Primary Completion

June 1, 2013

Study Completion

December 1, 2017

Last Updated

March 25, 2020

Record last verified: 2020-03

Locations