Study on the Effect of Fish Oil and Appetite
1 other identifier
interventional
20
1 country
1
Brief Summary
20 normal-weight healthy subjects (10 males, 10 females) were in two periods given 10 of 0.5-mL capsules/day of fish oil and soybean oil for 3 weeks. In the end of each period they were given a standard breakfast and asked to report their appetite on visual analogue scales (VAS) immediately before and after the meal. The results were analyzed in accordance with the paired design under consideration of both supplement sequence and gender.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for early_phase_1 obesity
Started Oct 2011
Shorter than P25 for early_phase_1 obesity
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2011
CompletedPrimary Completion
Last participant's last visit for primary outcome
November 1, 2011
CompletedStudy Completion
Last participant's last visit for all outcomes
November 1, 2011
CompletedFirst Submitted
Initial submission to the registry
May 14, 2012
CompletedFirst Posted
Study publicly available on registry
September 26, 2012
CompletedNovember 12, 2012
September 1, 2012
1 month
May 14, 2012
November 9, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Appetite and satiation
Appetite and satiation were measured by visual analogue scales (VAS), which assessed satiation, hunger, fullness and desire to eat. Each scale was 100 mm in length with words anchored at each end, expressing the most positive and negative rating of each category.
October 7th - November 25th 2011
Secondary Outcomes (1)
Weight change
October 7th - November 25th 2011
Study Arms (2)
Fish oil
EXPERIMENTAL5 g/d in 10 capsules, providing 3.5 g of long-chain n-3 fatty acids
Soy bean oil
PLACEBO COMPARATOR5 g/d in 10 capsules
Interventions
For 3 weeks 5 g/d in 10 capsules, providing 3.5 g long-chain n-3 fatty acids in the fish oil period. Cross-over between arms with 1 week of wash out
Eligibility Criteria
You may qualify if:
- Normal weight (18.5\<BMI\<25 kg/m2).
- Healthy.
You may not qualify if:
- Subjects taking medication that could influence appetite.
- Subjects with special nutritional needs e.g. pregnant and lactating, seriously ill or old people.
- Subjects that had had fish oil-supplements for four weeks prior to the intervention period.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- AAstruplead
Study Sites (1)
Department of Human Nutrition
Frederiksberg, 1958, Denmark
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Lotte Lauritzen, PhD
Department of Human Nutrition
Study Design
- Study Type
- interventional
- Phase
- early phase 1
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- BASIC SCIENCE
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR INVESTIGATOR
- PI Title
- Associate Professore Lotte Lauritzen
Study Record Dates
First Submitted
May 14, 2012
First Posted
September 26, 2012
Study Start
October 1, 2011
Primary Completion
November 1, 2011
Study Completion
November 1, 2011
Last Updated
November 12, 2012
Record last verified: 2012-09