NCT01689818

Brief Summary

Poor sleep quality has been recognized as a major public health concern in the world. The prevalence of insomnia in Taiwan is comparable to that of Western countries. It is estimated that up to 50% of elderly complain about their sleep. Insomnia is associated with anxiety, falls, or cognitive impairment in the elderly, which may compromise their daily activities function and quality of life. Recently, researches have demonstrated the associations between insomnia and endocrine system dysfunction, metabolic disorders, and cardiovascular events and death. Therefore, it is an important issue to improve sleep quality of the elders. The side-effects of pharmacological treatments and high-cost of cognitive behavior therapy limit their accessibility and effectiveness, and exercise training has been expected to provide an alternative intervention for insomnia. However, the long-term impact of insomnia on health-related fitness and metabolic function, and the effect of exercise training remain inconclusive. Therefore, the study hypothesis is that exercise training affect functional performance and quality of life in community-dwelling elderly with insomnia.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
250

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Aug 2011

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2011

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

August 28, 2012

Completed
24 days until next milestone

First Posted

Study publicly available on registry

September 21, 2012

Completed
1.8 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2014

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2014

Completed
Last Updated

September 21, 2012

Status Verified

September 1, 2012

Enrollment Period

2.9 years

First QC Date

August 28, 2012

Last Update Submit

September 20, 2012

Conditions

Keywords

insomnia, elderly, exercise training

Outcome Measures

Primary Outcomes (1)

  • functional performance

    physical fitness and physical disability

    16 weeks

Secondary Outcomes (1)

  • depression

    16 weeks

Other Outcomes (1)

  • cognitive function

    16 weeks

Study Arms (2)

exercise training

EXPERIMENTAL

exercise training program which included aerobic exercise for 3 times per week.

Other: exercise training

control

NO INTERVENTION

lifestyle counseling

Interventions

exercise training program which included aerobic exercise for 3 times per week.

exercise training

Eligibility Criteria

Age65 Years+
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • above 65 y/o elderly

You may not qualify if:

  • psychiatric diagnosis (DSM-IV) of serious mental illness, including severe depression symptoms, mania, Alcohol or drug abuse
  • with other sleep disorders such as sleep apnea, periodic limb twitching, or fast moving eye movement behavior disorder
  • cognitive and other neurological diseases history who can not communicate
  • Unstable serious illness or sports contraindicated cardiopulmonary disease such as diabetes, hypertension, and other cardiovascular disease, neurological injury patients
  • body mass index greater than 35 kg/ M 2 or more

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Meng-Yueh Chien

Taipei, Taiwan

RECRUITING

Related Publications (1)

  • Chien MY, Chen HC. Poor sleep quality is independently associated with physical disability in older adults. J Clin Sleep Med. 2015 Mar 15;11(3):225-32. doi: 10.5664/jcsm.4532.

MeSH Terms

Conditions

Sleep Initiation and Maintenance Disorders

Interventions

Exercise

Condition Hierarchy (Ancestors)

Sleep Disorders, IntrinsicDyssomniasSleep Wake DisordersNervous System DiseasesMental Disorders

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Officials

  • Meng-Yueh Chien, PhD

    National Taiwan University

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Meng-Yueh Chien, Ph.D

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 28, 2012

First Posted

September 21, 2012

Study Start

August 1, 2011

Primary Completion

July 1, 2014

Study Completion

July 1, 2014

Last Updated

September 21, 2012

Record last verified: 2012-09

Locations