NCT01683487

Brief Summary

I. To investigate time measurement from emergency room admission to first antibiotic administration. II. To evaluate risk factors for prolonged time to first antibiotic administration. III. To correlate time measurement with Charlson comorbidity index and multimorbidity patterns. IV. To investigate the impact of a delayed time to first antibiotic administration on the outcome

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
122

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Oct 2012

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 7, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 11, 2012

Completed
20 days until next milestone

Study Start

First participant enrolled

October 1, 2012

Completed
1.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2013

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2014

Completed
Last Updated

May 28, 2014

Status Verified

May 1, 2014

Enrollment Period

1.2 years

First QC Date

September 7, 2012

Last Update Submit

May 26, 2014

Conditions

Community-acquired Pneumonia

Outcome Measures

Primary Outcomes (1)

  • In-hospital mortaliy

    Mortality during hospitalization because of pneumococcal pneumonia

    From day of admission until discharge or dead

Interventions

ObservationPROCEDURE

Observational study only, no intervention.

Eligibility Criteria

Age16 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients admitted and treated at the University Hospital of Zurich because of severe community-acquired pneumococcal pneumonia requiring hospilazation.

You may qualify if:

  • detection of Streptococcus pneumoniae in blood cultures, tracheal secretion or sputum OR/AND
  • positive urinary pneumococcal antigen AND
  • presence of cough and presence of one of the following signs/symptoms: new focal chest signs; dyspnoea; tachypnoea; fever AND
  • radiologic signs of pneumonia

You may not qualify if:

  • Hospital-acquired or ventilator-associated pneumonia
  • Patients referred from or transferred to another hospital

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Zurich, Division of Internal Medicine

Zurich, Canton of Zurich, 8091, Switzerland

Location

MeSH Terms

Conditions

Community-Acquired Pneumonia

Interventions

Observation

Condition Hierarchy (Ancestors)

Community-Acquired InfectionsInfectionsPneumoniaRespiratory Tract InfectionsRespiratory Tract Diseases

Intervention Hierarchy (Ancestors)

MethodsInvestigative Techniques

Study Officials

  • Daniel Franzen, MD

    University Hospital Zurich, Division of Internal Medicine

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 7, 2012

First Posted

September 11, 2012

Study Start

October 1, 2012

Primary Completion

December 1, 2013

Study Completion

May 1, 2014

Last Updated

May 28, 2014

Record last verified: 2014-05

Locations

CH(1)