Clinical Pediatric Pneumonia Score in Critically Ill Children

NCT02139384 | Withdrawn

• 1 other identifier: 5110327
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to create a clinical pneumonia tool that can be used to predict the cause of community-acquired pneumonia, which is a lung infection that began outside of the hospital in critically ill children therefore limiting unnecessary antibiotic use. The investigators will enroll critically ill children admitted with acute respiratory failure and suspected pneumonia. Each patient will receive a clinical pneumonia score blinded from culture and respiratory viral panel results. All care after samples obtained will be at the discretion of the PICU team. The investigators believe that our clinical pneumonia scale with procalcitonin will accurately designate viral from bacterial etiologies.

Conditions

Community Acquired Pneumonia

Keywords

procalcitonin; community acquired pneumonia; pneumonia score

Outcome Measures

Primary Outcomes (1)

• Can our proposed pneumonia score distinguish community acquired bacterial pneumonia from community acquired viral pneumonia

  6 months

Eligibility Criteria

• Age: 1 Day - 21 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)

Study Population

critically ill children admitted the the LLU PICU with acute respiratory failure with suspected community-acquired pneumonia

You may qualify if:

• All intubated pediatric patients
• Age 1 day to 21 years
• Admitted to the LLUCH PICU with suspected pneumonia for the next 6 months
• Have received antibiotics for less than 12 hours
• Have been intubated for less than 24 hours
• Patients must be English or Spanish speaking for consent purposes.

You may not qualify if:

• Patients who have received antibiotics for greater than 12 hours
• Patients who have been intubated for greater than 24 hours
• Patients who are unable to tolerate non-bronchoscopic bronchoalveolar lavage

Sponsors & Collaborators

• Loma Linda University: lead

Study Sites (1)

Loma Linda University Children's Hospital

Loma Linda, California, 92354, United States

Location

MeSH Terms

Conditions

Community-Acquired Pneumonia

Condition Hierarchy (Ancestors)

Community-Acquired Infections; Infections; Pneumonia; Respiratory Tract Infections; Respiratory Tract Diseases

Study Officials

• Cynthia Tinsley, M.D.

  Loma Linda University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 8, 2014
• First Posted: May 15, 2014
• Study Start: August 1, 2012
• Primary Completion: January 1, 2013
• Study Completion: January 1, 2013
• Last Updated: April 25, 2017

Record last verified: 2017-04

Locations

US (1)