Assessment of Hemodynamic Response During Intubation Between Rigid Laryngoscopy and Track Light in Coronary Patients
Randomized Clinical Trials to Compare the Hemodynamic Response During Intubation Between Rigid Laryngoscopy and Track Light in Coronary Patients Undergoing CABG
1 other identifier
interventional
40
1 country
1
Brief Summary
Opioids provide greater patient comfort during intubation, but are not able to abolish completely the release adrenergic hormones during the laryngoscopy, which may cause undesirable hemodynamic changes. In this study the investigators selected two techniques commonly used for intubation, laryngoscopy and track light, so the investigators can verify which intubation techniques provides less hemodynamic changes in coronary patients under standard anesthesia induction.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_4
Started Feb 2010
Shorter than P25 for phase_4
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2010
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 1, 2010
CompletedStudy Completion
Last participant's last visit for all outcomes
March 1, 2010
CompletedFirst Submitted
Initial submission to the registry
April 1, 2010
CompletedFirst Posted
Study publicly available on registry
September 11, 2012
CompletedSeptember 11, 2012
April 1, 2012
28 days
April 1, 2010
September 10, 2012
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
hemodynamic response
tracheal intubation with track light release less adrenergic hormones than laryngoscopy intubation
patient prepare (baseline), 1min after induction, 5 min after induction, 1 min after intubation
Study Arms (2)
Laryngoscopy
ACTIVE COMPARATORLaryngoscopy Track Light teaqueal intubation
Track Light
ACTIVE COMPARATORInterventions
tracheal intubation with two different techniques, track light and laryngoscopy.
Eligibility Criteria
You may qualify if:
- coronary disease ASA 2 e 3 using beta-blockers
You may not qualify if:
- emergency surgery arrythmia other antiarrythmic drugs
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Institute of Cardiology / Ministry of Health
Rio de Janeiro, Rio de Janeiro, 22240-005, Brazil
Related Publications (3)
Nishiyama T, Misawa K, Yokoyama T, Hanaoka K. Effects of combining midazolam and barbiturate on the response to tracheal intubation: changes in autonomic nervous system. J Clin Anesth. 2002 Aug;14(5):344-8. doi: 10.1016/s0952-8180(02)00370-7.
PMID: 12208438BACKGROUNDNora FS, Klipel R, Ayala G, Oliveira Filho GR. [Remifentanil: does the infusion regimen make a difference in the prevention of hemodynamic responses to tracheal intubation?]. Rev Bras Anestesiol. 2007 Jun;57(3):247-60. doi: 10.1590/s0034-70942007000300003. Portuguese.
PMID: 19466360RESULTAlmeida MC, Martins RS, Martins AL. [Tracheal intubation conditions at 60 seconds in children, adults and elderly patients.]. Rev Bras Anestesiol. 2004 Apr;54(2):204-11. doi: 10.1590/s0034-70942004000200007. Portuguese.
PMID: 19471727RESULT
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Marcello F Salgado filho, MD
Federal University of Juiz de Fora
Study Design
- Study Type
- interventional
- Phase
- phase 4
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Master
Study Record Dates
First Submitted
April 1, 2010
First Posted
September 11, 2012
Study Start
February 1, 2010
Primary Completion
March 1, 2010
Study Completion
March 1, 2010
Last Updated
September 11, 2012
Record last verified: 2012-04