NCT01682122

Brief Summary

Wide Pulse Pressure is frequently present in the normal, full-term neonatal population. This study will evaluate the frequency and persistence of wide pulse pressure in the neonatal population. Using a prospective study design in the Regular newborn and Observation nurseries of SIUH, North site. Healthy newborns that are between 0-72 hrs of age will have their blood pressures measured using the oscillometric method. This data will offer insight into whether the presence of wide pulse pressure in otherwise healthy newborn infants warrants further cardiovascular evaluation

Trial Health

55
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Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
196

participants targeted

Target at P50-P75 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2012

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

September 5, 2012

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 10, 2012

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2013

Completed
Last Updated

September 10, 2012

Status Verified

September 1, 2012

Enrollment Period

1 year

First QC Date

September 5, 2012

Last Update Submit

September 7, 2012

Conditions

Keywords

Blood PressurePediatricsInfant, NewbornCardiology

Outcome Measures

Primary Outcomes (1)

  • incidence of wide pulse pressures in healthy newborn

    This study will determine the incidence of wide pulse pressures in healthy newborn infants during the first days of life.

    15 mins a day

Study Arms (1)

Newborns

Healthy newborns in Regular and Observation nurseries who are between 0-72 hrs of age. Infants with gestational age \> or = 35weeks and birth weight \> 2500g, who are hemodynamically stable, have no cardiorespiratory abnormalities and have no evidence of sepsis. If a blood culture was drawn due to the presence of maternal risk factors (e.g. maternal fever, prolonged rupture of membranes), patients will be included only if the blood culture result is negative and in case of intrapartum antibiotic treatment, ancillary blood tests (CBC with differential, CRP) are also within the normal range

Eligibility Criteria

AgeUp to 72 Hours
Sexall
Healthy VolunteersYes
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

Healthy newborns in Regular and Observation nurseries who are between 0-72 hrs of age.

You may qualify if:

  • Infants with gestational age \> or = 35weeks and birth weight \> 2500g, who are hemodynamically stable, have no cardiorespiratory abnormalities and have no evidence of sepsis. If a blood culture was drawn due to the presence of maternal risk factors (e.g. maternal fever, prolonged rupture of membranes), patients will be included only if the blood culture result is negative and in case of intrapartum antibiotic treatment, ancillary blood tests (CBC with differential, CRP) are also within the normal range

You may not qualify if:

  • Infants with gestational age \< 35weeks or birth weight \< 2500g and with evidence of neonatal sepsis either culture proven or clinically suspected.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Staten Island University Hospital

Staten Island, New York, 10305, United States

Location

Related Links

Central Study Contacts

Philip Roth, MD, PhD

CONTACT

Omar Rodriguez, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director of Neonatology Chairman, Dept. of Pediatrics, & Vice President of Medical Education

Study Record Dates

First Submitted

September 5, 2012

First Posted

September 10, 2012

Study Start

August 1, 2012

Primary Completion

August 1, 2013

Last Updated

September 10, 2012

Record last verified: 2012-09

Locations