NCT01646216

Brief Summary

The purpose of this study is to determine whether split belt or conventional treadmill training can be used to treat walking pattern deficits from stroke and to determine whether this improves gait asymmetry and metabolic efficiency.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
34

participants targeted

Target at P25-P50 for not_applicable stroke

Timeline
Completed

Started Jun 2012

Longer than P75 for not_applicable stroke

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 5, 2012

Completed
2 months until next milestone

Study Start

First participant enrolled

June 7, 2012

Completed
1 month until next milestone

First Posted

Study publicly available on registry

July 20, 2012

Completed
4.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 24, 2017

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 30, 2017

Completed
7 months until next milestone

Results Posted

Study results publicly available

May 4, 2018

Completed
Last Updated

January 14, 2019

Status Verified

January 1, 2019

Enrollment Period

4.7 years

First QC Date

April 5, 2012

Results QC Date

December 1, 2017

Last Update Submit

January 10, 2019

Conditions

Keywords

stroketreadmillwalkinghemiparesistraining

Outcome Measures

Primary Outcomes (1)

  • Change in Baseline Step Length Symmetry. That is, Whether the Steps With Right and Left Legs Are the Same Length.

    Subjects will either walk on a special mat that records their step lengths, or will wear special markers on the feet and body to record their step lengths.

    After training (week 14), and 3 months after training

Secondary Outcomes (2)

  • Change in Baseline Oxygen Intake

    Post training (week 14), and 3 months follow up

  • Walking Speed

    Baseline, post training, and 3 month follow up.

Study Arms (1)

Split-belt treadmill training

EXPERIMENTAL

Split-belt treadmill exercise

Behavioral: Split belt treadmill

Interventions

A split belt treadmill is like a typical treadmill that is seen in the gym, except that this treadmill has two belts that move instead of just one. One leg goes on one belt and the other leg uses the other belt. The belt speeds can be set to move at the same speed, making this treadmill similar to any regular treadmill, but, belt speeds can also be set so that one belt moves a little faster than the other. The belts are never set at a running or jogging speed, only a self-paced walking speed regardless of whether the belts are both going the same or slightly different speeds.

Also known as: Woodway Split Belt Treadmill, Company: Woodway USA, Inc
Split-belt treadmill training

Eligibility Criteria

Age20 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • stroke or hemiparesis (\>6 months post stroke)
  • able to walk but has residual gait deficit (including those who walk with a cane or walker)
  • This is their first and only stroke
  • Able to walk for 5 minutes at their self-paced speed
  • Adults age 20-80

You may not qualify if:

  • Cerebellar signs (e.g.ataxic hemiparesis)
  • Any neurologic condition other than stroke
  • Insulin dependent diabetes
  • Congestive heart failure
  • Peripheral artery disease with claudication
  • Pulmonary or renal failure
  • Unstable angina
  • Uncontrolled hypertension (\>190/110 mmHg)
  • Dementia
  • Severe aphasia
  • Orthopedic or pain conditions that limit walking
  • Total joint replacement in the lower extremities
  • Pregnancy

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Motion Analysis Lab in the Kennedy Krieger Institute

Baltimore, Maryland, 21205, United States

Location

Related Links

MeSH Terms

Conditions

StrokeParesis

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Limitations and Caveats

Some subjects could not complete all of the tasks. Recruitment was also challenging.

Results Point of Contact

Title
Anthony Gonzalez
Organization
Kennedy Krieger Institute

Study Officials

  • Amy J Bastian, PhD, PT

    Kennedy Krieger Institute and Johns Hopkins School of Medicine

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Model Details: Split belt treadmill
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Dr. Amy J Bastian, Ph.D., PT

Study Record Dates

First Submitted

April 5, 2012

First Posted

July 20, 2012

Study Start

June 7, 2012

Primary Completion

February 24, 2017

Study Completion

September 30, 2017

Last Updated

January 14, 2019

Results First Posted

May 4, 2018

Record last verified: 2019-01

Locations