NCT01644058

Brief Summary

Objective: To provide 2-year clinical- and patient-oriented data with regard to mandibular overdenture assisted by 2 immediately loaded unsplinted implants.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
18

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jun 2011

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2011

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

July 16, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

July 18, 2012

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 1, 2013

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2013

Completed
1.2 years until next milestone

Results Posted

Study results publicly available

May 6, 2014

Completed
Last Updated

June 2, 2017

Status Verified

May 1, 2017

Enrollment Period

1.8 years

First QC Date

July 16, 2012

Results QC Date

August 26, 2013

Last Update Submit

May 1, 2017

Conditions

Keywords

immediate-loadingpatient-based outcomes

Outcome Measures

Primary Outcomes (2)

  • Patient Satisfaction With the Immediate Loading Protocol

    Visual Analogue Scale (VAS) to assess patients' satisfaction, with a score of 100 being extremely satisfied (minimum and maximum scores: 1-100 respectively).

    4 months

  • Oral-health-related Quality of Life With the Immediate Loading Protocol

    Oral Health Impact Profile (OHIP-20) to assess oral-health-related quality of life: score ranges between 20 and 120 points, with a lower score indicating a better oral-health-related quality of life.

    4 months

Study Arms (1)

Immediate loading

EXPERIMENTAL

Immediate loading of 2 endo-osseous mandibular implants

Procedure: Immediate loading

Interventions

Also known as: Procedure: Immediate loading of 2 endo-osseous unsplinted implants of a mandibular overdenture
Immediate loading

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Minimal age of 18 years
  • Complete edentulism for more than 1 year
  • Wear of total conventional prosthesis for more than 1 year
  • Bone morphology in the anterior mandibular region amendable for the placement of 3 regular diameter implants without any additional procedure (graft or membrane).

You may not qualify if:

  • Any absolute or relative contra-indication to implant therapy
  • Physical incapacity to render oral or prosthetic hygiene
  • Incapacity to obtain a free and informed consent
  • Incapacity to assist to planned follow up appointments
  • Incapacity to understand and complete questionnaires
  • Inadequate bone quality: IT\<35 Ncm
  • Inadequate primary stability: ISQ\<60

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Université de Montréal

Montreal, Quebec, H3Y1P2, Canada

Location

MeSH Terms

Interventions

Immediate Dental Implant Loading

Intervention Hierarchy (Ancestors)

Dental Implantation, EndosseousDental ImplantationOral Surgical Procedures, PreprostheticOral Surgical ProceduresSurgical Procedures, OperativeProsthesis ImplantationDentistryProsthodontics

Limitations and Caveats

Phase-I clinical trial with small sample size and a pre-post design with no control group.

Results Point of Contact

Title
Elham Emami, DDS, MSc, PhD
Organization
Université de Montréal

Study Officials

  • Elham Emami, DDS, MSc,PhD

    Université de Montréal, Faculty of Dentistry

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Masking Details
Investigators were not involved in data analysis
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
D.D.S., M. Sc., Ph. D, Professor

Study Record Dates

First Submitted

July 16, 2012

First Posted

July 18, 2012

Study Start

June 1, 2011

Primary Completion

March 1, 2013

Study Completion

March 1, 2013

Last Updated

June 2, 2017

Results First Posted

May 6, 2014

Record last verified: 2017-05

Locations