Motor Training for Fall Prevention

NCT01621958 | Completed

• 2 other identifiers: 2001-08215R01AG029616-03
• Study Type: interventional
• Target: 212
• Locations: 1 country
• Sites: 1

Brief Summary

Slip-related falls often cause injury; these often have catastrophic consequences, even among the healthiest older persons. Establishing a retainable preventive training regimen against slip-related falls would, without doubt, have major public health implications. In this study, investigators will demonstrate that older adults can significantly reduce their near-term risk of backward balance loss and falls through motor training with multiple protected slip exposure, and such adaptive improvements from such prophylactic training regimen can be retained over the course of a year.

Conditions

Fall Prevention

Keywords

balance loss; dynamic stability; motor learning; plasticity

Outcome Measures

Primary Outcomes (1)

• Fall incidence

  6 months

Secondary Outcomes (1)

• Dynamic stability

  6 months

Study Arms (2)

Motor training

EXPERIMENTAL

Behavioral: Repeated perturbation training

Intensity control

PLACEBO COMPARATOR

Behavioral: Minimal perturbation training

Interventions

Repeated perturbation training BEHAVIORAL

One session consisting of 24 slips total interspersed with 16 nonslip trials (1 block of 8 slips, 3 non-slips, 2nd block of 8 slips, 3 non-slips, a mixed block consisting of 8 slips and 10 non-slips). Retest consisting of one slip exposure at either 6 months, 9 months or 12 months.

Also known as: Repeated slip training

Motor training

Minimal perturbation training BEHAVIORAL

One session consisting of a single slip exposure. Retest consisting of one slip exposure at either 6 months, 9 months or 12 months.

Also known as: Single slip exposure

Intensity control

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)

You may qualify if:

• Subjects with no known history of musculoskeletal, neurological, cardiovascular, or pulmonary impairment that may affect their ability to perform the testing procedures will be included.
• Subjects in the balance-impaired group will specifically include subjects with unilateral or bilateral vestibular disorders and individuals with balance deterioration due to aging.
• Subjects in this group must be able ambulate independently for at least 5 meters and score 48/56 on the Berg Balance Scale, and must have no Central Nervous System disorders beyond vestibular disorders and no central/peripheral motor impairments.

You may not qualify if:

• using any sedative of any type,
• having known history of osteoporosis,
• having any clinically significant functional impairment related to a specific musculoskeletal, neurological, or cardiopulmonary disease,
• ultrasound calcaneus bone mineral density T score \< -1 (osteoporosis )
• Mini-Mental State exam score \< 25 (impaired cognition),
• timed up-and-go \> 13.5 sec (impaired mobility).

Sponsors & Collaborators

• University of Illinois at Chicago: lead
• National Institute on Aging (NIA): collaborator

Study Sites (1)

Clinical Gait and Movement Analysis Laboratory

Chicago, Illinois, 60612, United States

Location

Study Officials

• Yi-Chung Pai, PhD

  University of Illinois at Chicago

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Purpose: PREVENTION
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: June 12, 2012
• First Posted: June 18, 2012
• Study Start: September 1, 2008
• Primary Completion: April 1, 2012
• Study Completion: April 1, 2012
• Last Updated: November 6, 2019

Record last verified: 2019-11

Locations

US (1)