Stress Echocardiography Versus Coronary Angiography for Left Main Stenosis Detection

NCT01620320 | Withdrawn

• 1 other identifier: projet #10-011
• Study Type: observational
• Target: N/A
• Locations: 1 country
• Sites: 1

Brief Summary

Left main stenosis use to be treated by bypass but with the improvement of angioplasty techniques, an increasing number of patients are submit to left main coronary angioplasty. Consequences of left main intra stent stenosis can be disastrous yet, for the moment, no precise recommendation concerning the follow up of these patients exist. The investigators ought to determine if stress echocardiography can predict left main intra stent stenosis as well (non inferiorly)as control angiography that use to be done.

Conditions

Left Main Coronary Artery Disease; Stenosis

Keywords

Left main coronary artery; Coronary artery disease; Stress echography; Intrastent stenosis

Outcome Measures

Primary Outcomes (1)

• Correlation between stress echocardiography results for the detection of left main prosthesis stenosis with coronary angiogram results.

  9 to 12 months after left main angioplasty

Study Arms (1)

Stress echography

Nine to twelve months after their left main angioplasty, patients will go through a stress echo and then the usual control angiography (done routinely in most patient in our center). Patients will act as their own control.

Other: Stress echocardiography

Interventions

Stress echocardiography OTHER

Patients able to exercise will have a treadmill test + echography; the others will have a dobutamine echography.

Also known as: Dobutamine echocardiography, Treadmill echocardiography

Stress echography

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients presenting to teaching hospital or stent from community hospitals to teaching hospital and having left main angioplasty

You may qualify if:

• patients over 18 years old able to give consent and having had left main angioplasty.

You may not qualify if:

• Bypass on the left anterior descending coronary artery or left circumflex (" protected left main ")
• Treating physician judge that angiography need to be done straightaway
• Follow up elsewhere than the CHUS
• Patient refusal
• Pregnant women
• Stress echo contraindication(Severe high blood pressure or malignant arrhythmia)or condition that limits interpretation (Left bundle branch block or pacemaker rhythm)

Sponsors & Collaborators

• Université de Sherbrooke: lead

Study Sites (1)

Centre Hospitalier Universitaire de Sherbrooke, departement de cardiologie

Sherbrooke, Quebec, J1H 5N4, Canada

Location

MeSH Terms

Conditions

Coronary Artery Disease; Constriction, Pathologic

Condition Hierarchy (Ancestors)

Coronary Disease; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Arteriosclerosis; Arterial Occlusive Diseases; Vascular Diseases; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms

Study Officials

• Paul Farand, Cardiologue

  Centre de recherche du Centre hospitalier universitaire de Sherbrooke

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Doctor

Study Record Dates

• First Submitted: July 16, 2010
• First Posted: June 15, 2012
• Study Start: July 1, 2010
• Primary Completion: July 1, 2012
• Study Completion: July 1, 2013
• Last Updated: June 26, 2013

Record last verified: 2013-06

Locations

CA (1)