Valeriana Officinalis L. for Conscious Sedation in Patients Submitted to Impacted Lower Third Molars Surgery: A Randomized, Double-Blind, Placebo-Controlled Crossover Study
Sponsor study identifier
interventional
20
1 country
1
Study Start
March 2003
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
August 2003
Actual (reported)Study Completion
August 2003
Actual (reported)The aim of the present study was to evaluate the efficacy of Valeriana officinalis L. 100 mg in single oral doses one hour preoperative as conscious sedation during the impacted lower third molar surgery.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
August 2003
Actual (reported)Click on a node to explore related trials.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
March 2003
Date type not reportedThis date has not been verified as actual or estimated.
August 2003
Actual (reported)August 2003
Actual (reported)June 1, 2012
Actual (reported)June 5, 2012
Actual (reported)Signs and symptoms of anxiety
During each surgery, the researcher and surgeon observed the manifestation of signs and symptoms associated to anxiety (restlessness/agitation/nervous ticks, paleness, excessive perspiration, tingling sensation in hands, feet or lips, change in breathing rhythm or depth). In the presence of one or more of these signs and symptoms, the patient was classified as anxious. If there was no manifestation of anxiety, the patient was classified as calm or relaxed
1 day (during dental appointment)
assessment of the blood pressure
The assessment of the blood pressure was performed at three moments: baseline, post-medication and end of surgery.
1 day (during dental appointment)
Assesment of heart rate
The assessment of the heart rate was performed at three moments: baseline, post-medication and end of surgery.
1 day (during dental appointment)
Oxygen saturation
1 day (During dental appointment)
Side effects of drugs
1 week
100 mg of Valeriana officinalis L. (Valerian)
Placebo 100mg
A single dose of 100 mg of Valeriana officinalis L., 1 hour prior to surgical procedures
A single dose of 100 mg of placebo orally, 1 hour prior to surgical procedures
Oral-Maxillofacial Surgery Sector of the Piracicaba Dental School, Universidade Estadual de Campinas (Brazil)
Piracicaba, São Paulo, 13414-903, Brazil
Marcos Pinheiro, PhD
Federal University of the Valleys of Jequitinhonha and Mucuri
20 participants (actual enrollment reported by the registry).
First Submitted
June 1, 2012
First Posted
June 5, 2012
Study Start
March 2003
Ischemic Preconditioning in Resistance Exercise in Older Women
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This date has not been verified as actual or estimated.
Primary Completion
August 2003
Actual (reported)Study Completion
August 2003
Actual (reported)Last Updated
June 6, 2012
Record last verified: 2012-06
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Source: ClinicalTrials.gov.
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