NCT01608659

Brief Summary

This is a retrospective chart review to evaluate treatment patterns of botulinum toxin Type A for the treatment of facial lines.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
110

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Apr 2011

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2011

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 17, 2011

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 17, 2011

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

May 29, 2012

Completed
2 days until next milestone

First Posted

Study publicly available on registry

May 31, 2012

Completed
2 months until next milestone

Results Posted

Study results publicly available

August 1, 2012

Completed
Last Updated

April 17, 2019

Status Verified

April 1, 2019

Enrollment Period

3 months

First QC Date

May 29, 2012

Results QC Date

June 25, 2012

Last Update Submit

April 3, 2019

Conditions

Outcome Measures

Primary Outcomes (1)

  • Average Total Dose Per Treatment Period

    Average total dose per treatment period was defined as total treatment dose plus total touch-up dose plus total follow-up dose.

    24 Months

Secondary Outcomes (2)

  • Inter-Injection Interval Duration of Each Treatment Period

    24 Months

  • Percent of Subjects Reporting Satisfaction With Treatment Effects

    24 Months

Study Arms (1)

botulinum toxin Type A

Previous treatment with botulinum toxin Type A for treatment of facial lines

Drug: botulinum toxin Type A

Interventions

Previous treatment with botulinum toxin Type A for treatment of facial lines

Also known as: BOTOX®, Xeomin®
botulinum toxin Type A

Eligibility Criteria

Age18 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Subjects treated for glabellar lines (hyperfunctional facial lines) with botulinum toxin Type A

You may qualify if:

  • Previously treated for glabellar lines (hyperfunctional facial lines) with botulinum toxin Type A preparation
  • Received 2 treatment cycles wtih botulinum toxin Type A (BOTOX®) prior to at least 1 treatment with botulinum toxin Type A (Xeomin®)

You may not qualify if:

  • None

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Unknown Facility

Buenos Aires, Argentina

Location

Related Publications (1)

  • Banegas RA, Farache F, Rancati A, Chain M, Gallagher CJ, Chapman MA, Caulkins CA. The South American Glabellar Experience Study (SAGE): a multicenter retrospective analysis of real-world treatment patterns following the introduction of incobotulinumtoxinA in Argentina. Aesthet Surg J. 2013 Sep 1;33(7):1039-45. doi: 10.1177/1090820X13503475. Epub 2013 Aug 29.

    PMID: 23990584BACKGROUND

MeSH Terms

Interventions

Botulinum Toxins, Type AincobotulinumtoxinA

Intervention Hierarchy (Ancestors)

Botulinum ToxinsMetalloendopeptidasesEndopeptidasesPeptide HydrolasesHydrolasesEnzymesEnzymes and CoenzymesMetalloproteasesBacterial ProteinsProteinsAmino Acids, Peptides, and ProteinsBacterial ToxinsToxins, BiologicalBiological Factors

Results Point of Contact

Title
Vice President Medical Affairs,
Organization
Allergan, Inc

Study Officials

  • Medical Director

    Allergan

    STUDY DIRECTOR

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 29, 2012

First Posted

May 31, 2012

Study Start

April 1, 2011

Primary Completion

June 17, 2011

Study Completion

June 17, 2011

Last Updated

April 17, 2019

Results First Posted

August 1, 2012

Record last verified: 2019-04

Locations