NCT01604551|Completed
Membrane Shedding During Septic Shock
Membrane Shedding During Severe Sepsis and Septic Shock: Pathophysiological and Clinical Relevance
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Membrane Shedding During Severe Sepsis and Septic Shock: Pathophysiological and Clinical Relevance
Sponsor study identifier
observational
100
1 country
3
Study Start
May 2003
Date type not reportedThis date has not been verified as actual or estimated.
Primary Completion
Not reported
Date not reportedStudy Completion
December 2011
Actual (reported)Microparticles (MPs) result from plasma cell membrane remodeling and shedding after cell stimulation or apoptosis. MPs are know recognized as a pool of bioactive messengers with emerging role in pathophysiology of immune and cardiovascular diseases. MPs have been characterized during septic shock and may contribute to dissemination of pro-inflammatory and procoagulant mediators. This is a prospective observational study of circulating MPs and blood coagulation in 100 septic shock patients admitted in 3 tertiary hospitals medical ICU at baseline (D1), D2, D3, D4 and D7.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
December 2011
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
May 2003
Date type not reportedThis date has not been verified as actual or estimated.
December 2011
Actual (reported)May 21, 2012
Actual (reported)May 23, 2012
Actual (reported)Patients with septic shock
Service Réanimation Médicale et Médecine Hyperbare, CHU
Angers, 49933, France
Centre Hospitalier
Mulhouse, 68070, France
Service de Réanimation Médicale, Nouvel Hôpital Civil, Hôpitaux Universitaires
Strasbourg, 67091, France
Xavier DELABRANCHE, MD
Service de Réanimation Médicale, Nouvel Hôpital Civil, Hôpitaux Universitaires de Strasbourg, France
100 participants (actual enrollment reported by the registry).
First Submitted
May 21, 2012
First Posted
May 23, 2012
Study Start
May 2003
Date type not reportedThis date has not been verified as actual or estimated.
Norepinephrine Weaning in Septic Patients
Contact the study team to confirm eligibility.
Study Completion
December 2011
Actual (reported)Last Updated
June 1, 2012
Record last verified: 2012-05
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Source: ClinicalTrials.gov.
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