NCT01601431

Brief Summary

This is a research study about the usefulness of transparent cap during screening colonoscopy. The purpose of the research is to test the usefulness of adding small cap to the tip of the colonoscope. the investigators hypothesis is that Cap assisted colonoscopy will improve the detection of adenomatous polyps (polyps which can become colon cancer later on) in comparison to the standard colonoscopy.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
440

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Mar 2012

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
terminated

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 29, 2012

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

May 14, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

May 18, 2012

Completed
2.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 2, 2015

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 2, 2015

Completed
3.3 years until next milestone

Results Posted

Study results publicly available

June 7, 2018

Completed
Last Updated

June 7, 2018

Status Verified

May 1, 2018

Enrollment Period

2.8 years

First QC Date

May 14, 2012

Results QC Date

May 15, 2017

Last Update Submit

May 10, 2018

Conditions

Keywords

Screening colonoscopy

Outcome Measures

Primary Outcomes (1)

  • ADR Differences in Hispanic Patients Undergoing a Screening Colonoscopy With and Without Cap.

    1\. Compare ADR between Hispanic patients undergoing a screening colonoscopy with and without cap.

    1 year

Study Arms (2)

Cap Assisted Colonoscopy

EXPERIMENTAL

Cap Assisted Colonoscopy uses a Cap which is a transparent hood which is attached to the distal end of the colonscope and allows depressing the colon folds in order to visualize hidden polyps behind the folds.

Device: Cap Assisted Colonoscopy

Conventional colonoscopy

ACTIVE COMPARATOR

A conventional colonoscopy does not use a Cap in order to perform the procedure

Device: Conventional colonoscopy

Interventions

Plastic transparent cap added to the distal end of the colonoscope which can increase adenoma detection rate

Cap Assisted Colonoscopy

Regular colonoscopy as per standard clinical guidelines

Conventional colonoscopy

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Adult Hispanic patients (18-80) who are undergoing colonoscopy for screening or surveillance purposes.

You may not qualify if:

  • Patients younger than 18 yrs old or older than 80 yrs.
  • Patients with a prior history of colonic surgeries
  • Patient with Crohns colitis or ulcerative colitis.
  • Patient with prior history of colon cancer
  • Patient with poor bowel preparation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Texas Tech University Health Sciences Center at El Paso

El Paso, Texas, 79905, United States

Location

MeSH Terms

Conditions

Adenoma

Condition Hierarchy (Ancestors)

Neoplasms, Glandular and EpithelialNeoplasms by Histologic TypeNeoplasms

Limitations and Caveats

single center study

Results Point of Contact

Title
Mohamed Othman, M.D.
Organization
Baylor College of Medicine

Study Officials

  • Mohamed O Othman, MD

    Texas Tech University Health Sciences Center

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

May 14, 2012

First Posted

May 18, 2012

Study Start

March 29, 2012

Primary Completion

February 2, 2015

Study Completion

February 2, 2015

Last Updated

June 7, 2018

Results First Posted

June 7, 2018

Record last verified: 2018-05

Data Sharing

IPD Sharing
Will not share

Locations