S1202: Duloxetine Hydrochloride for Muscle/Joint Pain in Early-Stage Breast Cancer Receiving Hormone Therapy

NCT01598298 | Completed Phase 3 Results DMC

• 3 other identifiers: S1202U10CA037429NCI-2012-01960
• Study Type: interventional
• Target: 299
• Locations: 1 country
• Sites: 714

Brief Summary

RATIONALE: Duloxetine hydrochloride may lessen muscle, bone, and joint pain caused by hormone therapy. It is not yet known whether duloxetine hydrochloride is more effective than a placebo in treating patients with muscle, bone, and joint pain caused by hormone therapy. PURPOSE: This randomized phase III trial studies how well duloxetine hydrochloride works compared to a placebo in treating muscle, bone, and joint pain in patients with early-stage breast cancer receiving hormone therapy.

Conditions

Breast Cancer; Musculoskeletal Complications; Pain

Keywords

estrogen receptor-positive breast cancer; progesterone receptor-positive breast cancer; stage IA breast cancer; stage IB breast cancer; stage II breast cancer; stage IIIA breast cancer; stage IIIB breast cancer; stage IIIC breast cancer; pain; musculoskeletal complications

Outcome Measures

Primary Outcomes (1)

• Average Joint Pain According to BPI-SF

  Average joint pain according to the Brief Pain Inventory - Short Form (BPI-SF) average pain score (item #4). This item has a scale of 0 to 10 with 0 indicating "No pain" and 10 indicating "Pain as bad as you can imagine".

  Weeks 2, 6, 12, and 24; Week 12 reported

Secondary Outcomes (2)

• Worst Joint Pain According to the BPI-SF

  Weeks 2, 6, 12, and 24; Week 12 reported

• Pain Interference According to the BPI-SF

  Weeks 2, 6, 12, and 24; Week 12 reported

Study Arms (2)

Arm I

EXPERIMENTAL

Patients receive duloxetine hydrochloride orally (PO) once daily (QD) on days 1-7, twice daily (BID) on days 8-84, and then QD on days 85-91.

Drug: duloxetine hydrochloride

Arm II

PLACEBO COMPARATOR

Patients receive placebo PO QD on days 1-7, BID on days 8-84, and then QD on days 85-91.

Other: placebo

Interventions

duloxetine hydrochloride DRUG

Given PO

Also known as: NSC-744012

Arm I

placebo OTHER

Given PO

Arm II

Eligibility Criteria

• Age: Up to 120 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

DISEASE CHARACTERISTICS: * Patients must be women with histologically confirmed estrogen receptor (ER)- and/or progesterone receptor (PgR)-positive invasive carcinoma of the breast with no evidence of metastatic disease (M0) * Patients must have completed mastectomy or breast-sparing surgery and must have recovered from all side effects of the surgery * Patients must have aromatase inhibitor (AI)-associated musculoskeletal symptoms that began or increased after starting AI therapy; new musculoskeletal pain must not be due specifically to fracture or traumatic injury * Patients must have completed the S1202 Brief Pain Inventory-Short Form (BPI-SF) within 7 days prior to registration; patients must have an "average pain" of at least 4 on the BPI-SF PATIENT CHARACTERISTICS: * Patients must be post-menopausal, as defined by at least one of the following: * At least 12 months since the last menstrual period * Prior bilateral oophorectomy * Previous hysterectomy with one or both ovaries left in place (or previous hysterectomy in which documentation of bilateral oophorectomy is unavailable) AND follicle-stimulating hormone (FSH) values consistent with the institutional normal values for the post menopausal state; if patient is under the age of 55, FSH levels must be obtained within 28 days prior to registration OR * Have been on LHRH agonist therapy for at least 3 months and estradiol levels drawn within 28 days prior to registration are consistent with the institutional normal values for post-menopausal state. * Patients must have Zubrod performance status of 0-2 * Patients must have no known allergy or hypersensitivity to duloxetine or any of the inactive ingredients in the matching placebo * Patients must not have any contraindicated concurrent illnesses listed on the duloxetine package insert including: * Current primary psychiatric diagnosis (schizophrenia, psychosis) or suicidal ideation, history of bipolar disorder, or seizure disorder * History of alcohol or other substance abuse or dependence within 365 days prior to registration * Chronic liver disease * End-stage renal disease * Uncontrolled narrow-angle glaucoma * Clinically significant coagulation disorder * Creatinine clearance \> 30 mL/min * Aspartate aminotransferase (AST) and alanine aminotransferase (ALT) both within 3 x upper limit of normal * Total bilirubin within the upper limit of normal * Patients must be able to complete study questionnaires in English or Spanish * Patients must not have concurrent medical/arthritic disease that could confound or interfere with evaluation of pain or efficacy including: inflammatory arthritis (rheumatoid arthritis, systemic lupus, spondyloarthropathy, psoriatic arthritis, polymyalgia rheumatica), or cancer involving the bone * Patients must be willing to submit blood samples for correlative studies; baseline samples must be obtained prior to beginning protocol treatment PRIOR CONCURRENT THERAPY: * See Disease Characteristics * If patients were treated with chemotherapy and/or radiation therapy, these treatments must be completed at least 28 days prior to study registration * Concurrent bisphosphonate and trastuzumab therapies are allowed * Patients should have recovered from all Grade 2 or higher side effects of chemotherapy and/or radiation therapy with the exception of alopecia and peripheral neuropathy * Patients must currently be taking one of the following aromatase inhibitor (AI) doses for at least 21 days, but no longer than 12 months, prior to registration and plans to continue for at least an additional 180 days after registration * Anastrozole (Arimidex®) 1 mg daily * Letrozole (Femara®) 2.5 mg daily * Exemestane (Aromasin®) 25 mg daily * Patients must not be taking any contraindicated medications listed on the duloxetine package insert including the following: treatment with phenothiazines, propafenone, flecainide, or linezolid; treatment with monoamine oxidase (MAO)-inhibitor within 14 days prior to registration; or current use of anticoagulation medication (e.g., heparin, warfarin) * Patients must not require selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephirine reuptake inhibitors (SNRIs), or tricyclic antidepressants during study participation; patients must have been able to taper and discontinue treatment with these medications at least 7 days prior to registration; patients must not have taken duloxetine or milnacipran within 90 days prior to registration * Patients who are receiving treatment with narcotics, tramadol, gabapentin, and/or pregabalin must have been taking a stable dose for at least 30 days prior to registration

Contact the study team to discuss eligibility requirements. They can help determine if this study is right for you.

Sponsors & Collaborators

• SWOG Cancer Research Network: lead
• National Cancer Institute (NCI): collaborator

Study Sites (714)

Alaska Breast Care and Surgery LLC

Anchorage, Alaska, 99508, United States

Location

Anchorage Oncology Centre

Anchorage, Alaska, 99508, United States

Location

Katmai Oncology Group

Anchorage, Alaska, 99508, United States

Location

Providence Alaska Medical Center

Anchorage, Alaska, 99508, United States

Location

Fairbanks Memorial Hospital

Fairbanks, Alaska, 99701, United States

Location

Fowler Family Center for Cancer Care

Jonesboro, Arkansas, 72401, United States

Location

Kaiser Permanente-Deer Valley Medical Center

Antioch, California, 94531, United States

Location

Sutter Auburn Faith Hospital

Auburn, California, 95602, United States

Location

Alta Bates Summit Medical Center-Herrick Campus

Berkeley, California, 94704, United States

Location

Mills - Peninsula Hospitals

Burlingame, California, 94010, United States

Location

East Bay Radiation Oncology Center

Castro Valley, California, 94546, United States

Location

Eden Hospital Medical Center

Castro Valley, California, 94546, United States

Location

Valley Medical Oncology Consultants-Castro Valley

Castro Valley, California, 94546, United States

Location

Sutter Davis Hospital

Davis, California, 95616, United States

Location

Epic Care-Dublin

Dublin, California, 94568, United States

Location

Bay Area Breast Surgeons Inc

Emeryville, California, 94608, United States

Location

Epic Care Partners in Cancer Care

Emeryville, California, 94608, United States

Location

Kaiser Permanente-Fremont

Fremont, California, 94538, United States

Location

Valley Medical Oncology Consultants-Fremont

Fremont, California, 94538, United States

Location

Kaiser Permanente

Fresno, California, 93720, United States

Location

Loma Linda University Medical Center

Loma Linda, California, 92354, United States

Location

Cedars-Sinai Medical Center

Los Angeles, California, 90048, United States

Location

Contra Costa Regional Medical Center

Martinez, California, 94553-3156, United States

Location

Memorial Medical Center

Modesto, California, 95355, United States

Location

Kaiser Permanente-Modesto

Modesto, California, 95356, United States

Location

El Camino Hospital

Mountain View, California, 94040, United States

Location

Palo Alto Medical Foundation-Camino Division

Mountain View, California, 94040, United States

Location

Palo Alto Medical Foundation-Gynecologic Oncology

Mountain View, California, 94040, United States

Location

Sutter Cancer Research Consortium

Novato, California, 94945, United States

Location

Highland General Hospital

Oakland, California, 94602, United States

Location

Alta Bates Summit Medical Center - Summit Campus

Oakland, California, 94609, United States

Location

Bay Area Tumor Institute

Oakland, California, 94609, United States

Location

Hematology and Oncology Associates-Oakland

Oakland, California, 94609, United States

Location

Tom K Lee Inc

Oakland, California, 94609, United States

Location

Kaiser Permanente-Oakland

Oakland, California, 94611, United States

Location

Palo Alto Medical Foundation Health Care

Palo Alto, California, 94301, United States

Location

Huntington Memorial Hospital

Pasadena, California, 91105, United States

Location

Valley Medical Oncology Consultants

Pleasanton, California, 94588, United States

Location

Kaiser Permanente-Redwood City

Redwood City, California, 94063, United States

Location

Kaiser Permanente-Richmond

Richmond, California, 94801, United States

Location

Kaiser Permanente-Roseville

Roseville, California, 95661, United States

Location

Sutter Roseville Medical Center

Roseville, California, 95661, United States

Location

Sutter General Hospital

Sacramento, California, 95816, United States

Location

Kaiser Permanente-South Sacramento

Sacramento, California, 95823, United States

Location

Kaiser Permanente - Sacramento

Sacramento, California, 95825, United States

Location

California Pacific Medical Center-Pacific Campus

San Francisco, California, 94115, United States

Location

Kaiser Permanente-San Francisco

San Francisco, California, 94115, United States

Location

Kaiser Permanente-Santa Teresa-San Jose

San Jose, California, 95119, United States

Location

Kaiser Permanente San Leandro

San Leandro, California, 94577, United States

Location

Doctors Medical Center- JC Robinson Regional Cancer Center

San Pablo, California, 94806, United States

Location

Kaiser Permanente-San Rafael

San Rafael, California, 94903, United States

Location

Kaiser Permanente Medical Center - Santa Clara

Santa Clara, California, 95051, United States

Location

Palo Alto Medical Foundation-Santa Cruz

Santa Cruz, California, 95065, United States

Location

Kaiser Permanente-Santa Rosa

Santa Rosa, California, 95403, United States

Location

Sutter Pacific Medical Foundation

Santa Rosa, California, 95403, United States

Location

Kaiser Permanente-South San Francisco

South San Francisco, California, 94080, United States

Location

Kaiser Permanente-Stockton

Stockton, California, 95210, United States

Location

Palo Alto Medical Foundation-Sunnyvale

Sunnyvale, California, 94086, United States

Location

Northbay Cancer Center

Vacaville, California, 95687, United States

Location

Kaiser Permanente Medical Center-Vacaville

Vacaville, California, 95688, United States

Location

Kaiser Permanente-Vallejo

Vallejo, California, 94589, United States

Location

Sutter Solano Medical Center/Cancer Center

Vallejo, California, 94589, United States

Location

Kaiser Permanente-Walnut Creek

Walnut Creek, California, 94596, United States

Location

Presbyterian Intercommunity Hospital

Whittier, California, 90602, United States

Location

Rocky Mountain Cancer Centers-Aurora

Aurora, Colorado, 80012, United States

Location

The Medical Center of Aurora

Aurora, Colorado, 80012, United States

Location

Boulder Community Hospital

Boulder, Colorado, 80301, United States

Location

Rocky Mountain Cancer Centers-Boulder

Boulder, Colorado, 80304, United States

Location

Penrose-Saint Francis Healthcare

Colorado Springs, Colorado, 80907, United States

Location

Rocky Mountain Cancer Centers-Penrose

Colorado Springs, Colorado, 80907, United States

Location

Porter Adventist Hospital

Denver, Colorado, 80210, United States

Location

Colorado Blood Cancer Institute

Denver, Colorado, 80218, United States

Location

Presbyterian - Saint Lukes Medical Center - Health One

Denver, Colorado, 80218, United States

Location

Rocky Mountain Cancer Centers-Midtown

Denver, Colorado, 80218, United States

Location

SCL Health Saint Joseph Hospital

Denver, Colorado, 80218, United States

Location

Rocky Mountain Cancer Centers-Rose

Denver, Colorado, 80220, United States

Location

Rose Medical Center

Denver, Colorado, 80220, United States

Location

Colorado Cancer Research Program NCORP

Denver, Colorado, 80222, United States

Location

Mercy Medical Center

Durango, Colorado, 81301, United States

Location

Southwest Oncology PC

Durango, Colorado, 81301, United States

Location

Comprehensive Cancer Care and Research Institute of Colorado LLC

Englewood, Colorado, 80113, United States

Location

Swedish Medical Center

Englewood, Colorado, 80113, United States

Location

Mountain Blue Cancer Care Center

Golden, Colorado, 80401, United States

Location

North Colorado Medical Center

Greeley, Colorado, 80631, United States

Location

Rocky Mountain Cancer Centers-Greenwood Village

Greenwood Village, Colorado, 80111, United States

Location

Rocky Mountain Cancer Centers-Lakewood

Lakewood, Colorado, 80228, United States

Location

Saint Anthony Hospital

Lakewood, Colorado, 80228, United States

Location

Rocky Mountain Cancer Centers-Littleton

Littleton, Colorado, 80120, United States

Location

Littleton Adventist Hospital

Littleton, Colorado, 80122, United States

Location

Rocky Mountain Cancer Centers-Sky Ridge

Lone Tree, Colorado, 80124, United States

Location

Sky Ridge Medical Center

Lone Tree, Colorado, 80124, United States

Location

Longmont United Hospital

Longmont, Colorado, 80501, United States

Location

Rocky Mountain Cancer Centers-Longmont

Longmont, Colorado, 80501, United States

Location

McKee Medical Center

Loveland, Colorado, 80539, United States

Location

Parker Adventist Hospital

Parker, Colorado, 80138, United States

Location

Rocky Mountain Cancer Centers-Parker

Parker, Colorado, 80138, United States

Location

Saint Mary Corwin Medical Center

Pueblo, Colorado, 81004, United States

Location

Rocky Mountain Cancer Centers - Pueblo

Pueblo, Colorado, 81008, United States

Location

Rocky Mountain Cancer Centers-Thornton

Thornton, Colorado, 80260, United States

Location

SCL Health Lutheran Medical Center

Wheat Ridge, Colorado, 80033, United States

Location

University of Connecticut

Farmington, Connecticut, 06030, United States

Location

Greenwich Hospital

Greenwich, Connecticut, 06830, United States

Location

Smilow Cancer Hospital Care Center at Saint Francis

Hartford, Connecticut, 06105, United States

Location

Middlesex Hospital

Middletown, Connecticut, 06457, United States

Location

Kaiser Permanente-Capitol Hill Medical Center

Washington D.C., District of Columbia, 20002, United States

Location

Holy Cross Hospital

Fort Lauderdale, Florida, 33308, United States

Location

Jupiter Medical Center

Jupiter, Florida, 33458, United States

Location

Cancer Center of South Florida-Lake Worth

Lake Worth, Florida, 33461, United States

Location

The Watson Clinic

Lakeland, Florida, 33805, United States

Location

Mount Sinai Medical Center

Miami Beach, Florida, 33140, United States

Location

Florida Hospital Orlando

Orlando, Florida, 32803, United States

Location

Sacred Heart Hospital

Pensacola, Florida, 32504, United States

Location

University Cancer and Blood Center LLC

Athens, Georgia, 30607, United States

Location

Augusta University Medical Center

Augusta, Georgia, 30912, United States

Location

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

Savannah, Georgia, 31405, United States

Location

South Georgia Medical Center/Pearlman Cancer Center

Valdosta, Georgia, 31602, United States

Location

Hawaii Cancer Care Inc-POB II

Honolulu, Hawaii, 96813, United States

Location

Queen's Medical Center

Honolulu, Hawaii, 96813, United States

Location

Straub Clinic and Hospital

Honolulu, Hawaii, 96813, United States

Location

University of Hawaii Cancer Center

Honolulu, Hawaii, 96813, United States

Location

Hawaii Cancer Care Inc-Liliha

Honolulu, Hawaii, 96817, United States

Location

Hawaii Oncology Inc-Kuakini

Honolulu, Hawaii, 96817, United States

Location

Kaiser Permanente Moanalua Medical Center

Honolulu, Hawaii, 96819, United States

Location

Tripler Army Medical Center

Honolulu, Hawaii, 96859, United States

Location

Castle Medical Center

Kailua, Hawaii, 96734, United States

Location

Wilcox Memorial Hospital and Kauai Medical Clinic

Lihue, Hawaii, 96766, United States

Location

Hawaii Oncology Inc-Pali Momi

‘Aiea, Hawaii, 96701, United States

Location

Pali Momi Medical Center

‘Aiea, Hawaii, 96701, United States

Location

Saint Alphonsus Cancer Care Center-Boise

Boise, Idaho, 83706, United States

Location

Kootenai Medical Center

Coeur d'Alene, Idaho, 83814, United States

Location

Kootenai Cancer Center

Post Falls, Idaho, 83854, United States

Location

Kootenai Cancer Clinic

Sandpoint, Idaho, 83864, United States

Location

Rush - Copley Medical Center

Aurora, Illinois, 60504, United States

Location

Mac Neal Hospital

Berwyn, Illinois, 60402, United States

Location

Saint Joseph Medical Center

Bloomington, Illinois, 61701, United States

Location

Illinois CancerCare-Bloomington

Bloomington, Illinois, 61704, United States

Location

Illinois CancerCare-Canton

Canton, Illinois, 61520, United States

Location

Memorial Hospital of Carbondale

Carbondale, Illinois, 62902, United States

Location

Illinois CancerCare-Carthage

Carthage, Illinois, 62321, United States

Location

Centralia Oncology Clinic

Centralia, Illinois, 62801, United States

Location

University of Illinois

Chicago, Illinois, 60612, United States

Location

Weiss Memorial Hospital

Chicago, Illinois, 60640, United States

Location

Carle on Vermilion

Danville, Illinois, 61832, United States

Location

Cancer Care Center of Decatur

Decatur, Illinois, 62526, United States

Location

Decatur Memorial Hospital

Decatur, Illinois, 62526, United States

Location

Heartland Cancer Research NCORP

Decatur, Illinois, 62526, United States

Location

Carle Physician Group-Effingham

Effingham, Illinois, 62401, United States

Location

Crossroads Cancer Center

Effingham, Illinois, 62401, United States

Location

AMITA Health Alexian Brothers Medical Center

Elk Grove Village, Illinois, 60007, United States

Location

Elmhurst Memorial Hospital

Elmhurst, Illinois, 60126, United States

Location

Illinois CancerCare-Eureka

Eureka, Illinois, 61530, United States

Location

Little Company of Mary Hospital

Evergreen Park, Illinois, 60805, United States

Location

Illinois CancerCare-Galesburg

Galesburg, Illinois, 61401, United States

Location

Ingalls Memorial Hospital

Harvey, Illinois, 60426, United States

Location

Hinsdale Hematology Oncology Associates Incorporated

Hinsdale, Illinois, 60521, United States

Location

Illinois CancerCare-Kewanee Clinic

Kewanee, Illinois, 61443, United States

Location

Illinois CancerCare-Macomb

Macomb, Illinois, 61455, United States

Location

Carle Physician Group-Mattoon/Charleston

Mattoon, Illinois, 61938, United States

Location

Loyola University Medical Center

Maywood, Illinois, 60153, United States

Location

Illinois CancerCare-Monmouth

Monmouth, Illinois, 61462, United States

Location

Good Samaritan Regional Health Center

Mount Vernon, Illinois, 62864, United States

Location

Community Cancer Center Foundation

Normal, Illinois, 61761, United States

Location

Illinois CancerCare-Ottawa Clinic

Ottawa, Illinois, 61350, United States

Location

Radiation Oncology of Northern Illinois

Ottawa, Illinois, 61350, United States

Location

Illinois CancerCare-Pekin

Pekin, Illinois, 61554, United States

Location

OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center

Pekin, Illinois, 61554, United States

Location

Methodist Medical Center of Illinois

Peoria, Illinois, 61603, United States

Location

Illinois CancerCare-Peoria

Peoria, Illinois, 61615, United States

Location

OSF Saint Francis Radiation Oncology at Peoria Cancer Center

Peoria, Illinois, 61615, United States

Location

OSF Saint Francis Medical Center

Peoria, Illinois, 61637, United States

Location

Illinois CancerCare-Peru

Peru, Illinois, 61354, United States

Location

Valley Radiation Oncology

Peru, Illinois, 61354, United States

Location

Illinois CancerCare-Princeton

Princeton, Illinois, 61356, United States

Location

West Suburban Medical Center

River Forest, Illinois, 60305, United States

Location

Central Illinois Hematology Oncology Center

Springfield, Illinois, 62702, United States

Location

Southern Illinois University School of Medicine

Springfield, Illinois, 62702, United States

Location

Springfield Clinic

Springfield, Illinois, 62702, United States

Location

Memorial Medical Center

Springfield, Illinois, 62781, United States

Location

Cancer Care Specialists of Illinois-Swansea

Swansea, Illinois, 62226, United States

Location

Carle Cancer Center

Urbana, Illinois, 61801, United States

Location

The Carle Foundation Hospital

Urbana, Illinois, 61801, United States

Location

Northwestern Medicine Cancer Center Warrenville

Warrenville, Illinois, 60555, United States

Location

Rush-Copley Healthcare Center

Yorkville, Illinois, 60560, United States

Location

Michiana Hematology Oncology PC-Crown Point

Crown Point, Indiana, 46307, United States

Location

Elkhart Clinic

Elkhart, Indiana, 46514-2098, United States

Location

Michiana Hematology Oncology PC-Elkhart

Elkhart, Indiana, 46514, United States

Location

Elkhart General Hospital

Elkhart, Indiana, 46515, United States

Location

Community Hospital East

Indianapolis, Indiana, 46219, United States

Location

Community Regional Cancer Care-North

Indianapolis, Indiana, 46256, United States

Location

Community Howard Regional Health

Kokomo, Indiana, 46904, United States

Location

IU Health La Porte Hospital

La Porte, Indiana, 46350, United States

Location

Premier Oncology Hematology Associates

Merrillville, Indiana, 46410, United States

Location

Franciscan Saint Anthony Health-Michigan City

Michigan City, Indiana, 46360, United States

Location

Woodland Cancer Care Center

Michigan City, Indiana, 46360, United States

Location

Memorial Regional Cancer Center Day Road

Mishawaka, Indiana, 46544, United States

Location

Michiana Hematology Oncology PC-Mishawaka

Mishawaka, Indiana, 46545, United States

Location

Saint Joseph Regional Medical Center-Mishawaka

Mishawaka, Indiana, 46545, United States

Location

Michiana Hematology Oncology PC-Plymouth

Plymouth, Indiana, 46563, United States

Location

Reid Health

Richmond, Indiana, 47374, United States

Location

Memorial Hospital of South Bend

South Bend, Indiana, 46601, United States

Location

Michiana Hematology Oncology PC-South Bend

South Bend, Indiana, 46601, United States

Location

Northern Indiana Cancer Research Consortium

South Bend, Indiana, 46628, United States

Location

Porter Memorial Hospital

Valparaiso, Indiana, 46383, United States

Location

Michiana Hematology Oncology PC-Westville

Westville, Indiana, 46391, United States

Location

Mary Greeley Medical Center

Ames, Iowa, 50010, United States

Location

McFarland Clinic PC-William R Bliss Cancer Center

Ames, Iowa, 50010, United States

Location

McFarland Clinic PC-Boone

Boone, Iowa, 50036, United States

Location

Mercy Hospital

Cedar Rapids, Iowa, 52403, United States

Location

Oncology Associates at Mercy Medical Center

Cedar Rapids, Iowa, 52403, United States

Location

Medical Oncology and Hematology Associates-West Des Moines

Clive, Iowa, 50325, United States

Location

Iowa Methodist Medical Center

Des Moines, Iowa, 50309, United States

Location

Iowa-Wide Oncology Research Coalition NCORP

Des Moines, Iowa, 50309, United States

Location

Medical Oncology and Hematology Associates-Des Moines

Des Moines, Iowa, 50309, United States

Location

Medical Oncology and Hematology Associates-Laurel

Des Moines, Iowa, 50314, United States

Location

Iowa Lutheran Hospital

Des Moines, Iowa, 50316, United States

Location

JCHC McCreery Cancer Center

Fairfield, Iowa, 52556, United States

Location

McFarland Clinic PC-Trinity Cancer Center

Fort Dodge, Iowa, 50501, United States

Location

McFarland Clinic PC-Jefferson

Jefferson, Iowa, 50129, United States

Location

McFarland Clinic PC-Marshalltown

Marshalltown, Iowa, 50158, United States

Location

Mercy Medical Center - North Iowa

Mason City, Iowa, 50401, United States

Location

Ottumwa Regional Health Center

Ottumwa, Iowa, 52501, United States

Location

Siouxland Regional Cancer Center

Sioux City, Iowa, 51101, United States

Location

Mercy Medical Center-Sioux City

Sioux City, Iowa, 51104, United States

Location

Saint Luke's Regional Medical Center

Sioux City, Iowa, 51104, United States

Location

Methodist West Hospital

West Des Moines, Iowa, 50266-7700, United States

Location

Cancer Center of Kansas - Chanute

Chanute, Kansas, 66720, United States

Location

Cancer Center of Kansas - Dodge City

Dodge City, Kansas, 67801, United States

Location

Cancer Center of Kansas - El Dorado

El Dorado, Kansas, 67042, United States

Location

Cancer Center of Kansas - Fort Scott

Fort Scott, Kansas, 66701, United States

Location

Cancer Center of Kansas-Independence

Independence, Kansas, 67301, United States

Location

Cancer Center of Kansas-Kingman

Kingman, Kansas, 67068, United States

Location

Lawrence Memorial Hospital

Lawrence, Kansas, 66044, United States

Location

Cancer Center of Kansas-Liberal

Liberal, Kansas, 67905, United States

Location

Cancer Center of Kansas-Manhattan

Manhattan, Kansas, 66502, United States

Location

Cancer Center of Kansas - McPherson

McPherson, Kansas, 67460, United States

Location

Cancer Center of Kansas - Newton

Newton, Kansas, 67114, United States

Location

Menorah Medical Center

Overland Park, Kansas, 66209, United States

Location

Saint Luke's South Hospital

Overland Park, Kansas, 66213, United States

Location

Cancer Center of Kansas - Parsons

Parsons, Kansas, 67357, United States

Location

Kansas City NCI Community Oncology Research Program

Prairie Village, Kansas, 66208, United States

Location

Cancer Center of Kansas - Pratt

Pratt, Kansas, 67124, United States

Location

Cancer Center of Kansas - Salina

Salina, Kansas, 67401, United States

Location

Stormont-Vail Regional Health Center

Topeka, Kansas, 66604, United States

Location

Cancer Center of Kansas - Wellington

Wellington, Kansas, 67152, United States

Location

Associates In Womens Health

Wichita, Kansas, 67208, United States

Location

Cancer Center of Kansas-Wichita Medical Arts Tower

Wichita, Kansas, 67208, United States

Location

Cancer Center of Kansas - Wichita

Wichita, Kansas, 67214, United States

Location

Via Christi Regional Medical Center

Wichita, Kansas, 67214, United States

Location

Wichita NCI Community Oncology Research Program

Wichita, Kansas, 67214, United States

Location

Cancer Center of Kansas - Winfield

Winfield, Kansas, 67156, United States

Location

Baptist Health Corbin

Corbin, Kentucky, 40701, United States

Location

Oncology Hematology Care Inc-Crestview

Crestview Hills, Kentucky, 41017, United States

Location

Hardin Memorial Hospital

Elizabethtown, Kentucky, 42701, United States

Location

Baptist Health Lexington

Lexington, Kentucky, 40503, United States

Location

Baptist Health Louisville

Louisville, Kentucky, 40207, United States

Location

Baptist Health Madisonville/Merle Mahr Cancer Center

Madisonville, Kentucky, 42431, United States

Location

Owensboro Health Mitchell Memorial Cancer Center

Owensboro, Kentucky, 42303, United States

Location

Baptist Health Paducah

Paducah, Kentucky, 42003, United States

Location

Christus Saint Frances Cabrini Hospital

Alexandria, Louisiana, 71301, United States

Location

University Health-Conway

Monroe, Louisiana, 71202, United States

Location

Louisiana State University Health Sciences Center Shreveport

Shreveport, Louisiana, 71103, United States

Location

CHRISTUS Highland Medical Center

Shreveport, Louisiana, 71105, United States

Location

Harold Alfond Center for Cancer Care

Augusta, Maine, 04330, United States

Location

Eastern Maine Medical Center

Bangor, Maine, 04401, United States

Location

Central Maine Medical Center

Lewiston, Maine, 04240, United States

Location

Penobscot Bay Medical Center

Rockport, Maine, 04856, United States

Location

Kaiser Permanente-Woodlawn Medical Center

Baltimore, Maryland, 21244, United States

Location

Suburban Hospital

Bethesda, Maryland, 20814, United States

Location

Frederick Memorial Hospital

Frederick, Maryland, 21701, United States

Location

Kaiser Permanente-Gaithersburg Medical Center

Gaithersburg, Maryland, 20879, United States

Location

Kaiser Permanente - Largo Medical Center

Largo, Maryland, 20774, United States

Location

Sturdy Memorial Hospital

Attleboro, Massachusetts, 02703, United States

Location

Boston Medical Center

Boston, Massachusetts, 02118, United States

Location

Steward Saint Elizabeth's Medical Center

Brighton, Massachusetts, 02135, United States

Location

Saint Anne's Hospital

Fall River, Massachusetts, 02721, United States

Location

Simonds-Sinon Regional Cancer Center

Fitchburg, Massachusetts, 01420, United States

Location

Newton-Wellesley Hospital

Newton, Massachusetts, 02462, United States

Location

Norwood Hospital

Norwood, Massachusetts, 02062, United States

Location

Baystate Medical Center

Springfield, Massachusetts, 01199, United States

Location

University of Massachusetts Medical School

Worcester, Massachusetts, 01655, United States

Location

Bixby Medical Center

Adrian, Michigan, 49221, United States

Location

Hickman Cancer Center

Adrian, Michigan, 49221, United States

Location

Saint Joseph Mercy Hospital

Ann Arbor, Michigan, 48106-0995, United States

Location

Michigan Cancer Research Consortium NCORP

Ann Arbor, Michigan, 48106, United States

Location

University of Michigan Comprehensive Cancer Center

Ann Arbor, Michigan, 48109, United States

Location

Bronson Battle Creek

Battle Creek, Michigan, 49017, United States

Location

McLaren-Bay Region

Bay City, Michigan, 48706, United States

Location

Spectrum Health Big Rapids Hospital

Big Rapids, Michigan, 49307, United States

Location

Great Lakes Cancer Institute

Clarkston, Michigan, 48346, United States

Location

Beaumont Hospital-Dearborn

Dearborn, Michigan, 48124, United States

Location

Wayne State University/Karmanos Cancer Institute

Detroit, Michigan, 48201, United States

Location

Henry Ford Hospital

Detroit, Michigan, 48202, United States

Location

Saint John Hospital and Medical Center

Detroit, Michigan, 48236, United States

Location

Green Bay Oncology - Escanaba

Escanaba, Michigan, 49829, United States

Location

Weisberg Cancer Treatment Center

Farmington Hills, Michigan, 48334, United States

Location

Hurley Medical Center

Flint, Michigan, 48502, United States

Location

Genesys Hurley Cancer Institute

Flint, Michigan, 48503, United States

Location

Singh and Arora Hematology Oncology PC

Flint, Michigan, 48532, United States

Location

Cancer Research Consortium of West Michigan NCORP

Grand Rapids, Michigan, 49503, United States

Location

Mercy Health Saint Mary's

Grand Rapids, Michigan, 49503, United States

Location

Spectrum Health at Butterworth Campus

Grand Rapids, Michigan, 49503, United States

Location

Green Bay Oncology - Iron Mountain

Iron Mountain, Michigan, 49801, United States

Location

Allegiance Health

Jackson, Michigan, 49201, United States

Location

Borgess Medical Center

Kalamazoo, Michigan, 49001, United States

Location

Bronson Methodist Hospital

Kalamazoo, Michigan, 49007, United States

Location

West Michigan Cancer Center

Kalamazoo, Michigan, 49007, United States

Location

McLaren-Greater Lansing

Lansing, Michigan, 48910, United States

Location

Sparrow Hospital

Lansing, Michigan, 48912, United States

Location

Saint Mary Mercy Hospital

Livonia, Michigan, 48154, United States

Location

Mid-Michigan Medical Center - Midland

Midland, Michigan, 48670, United States

Location

Mercy Memorial Hospital

Monroe, Michigan, 48162, United States

Location

Toledo Clinic Cancer Centers-Monroe

Monroe, Michigan, 48162, United States

Location

McLaren Cancer Institute-Macomb

Mount Clemens, Michigan, 48043, United States

Location

McLaren Cancer Institute-Central Michigan

Mount Pleasant, Michigan, 48858, United States

Location

Mercy Health Mercy Campus

Muskegon, Michigan, 49444, United States

Location

Lakeland Community Hospital

Niles, Michigan, 49120, United States

Location

McLaren Cancer Institute-Northern Michigan

Petoskey, Michigan, 49770, United States

Location

Saint Joseph Mercy Oakland

Pontiac, Michigan, 48341, United States

Location

Lake Huron Medical Center

Port Huron, Michigan, 48060, United States

Location

Spectrum Health Reed City Hospital

Reed City, Michigan, 49677, United States

Location

William Beaumont Hospital-Royal Oak

Royal Oak, Michigan, 48073, United States

Location

Saint Mary's of Michigan

Saginaw, Michigan, 48601, United States

Location

Lakeland Hospital

Saint Joseph, Michigan, 49085, United States

Location

Marie Yeager Cancer Center

Saint Joseph, Michigan, 49085, United States

Location

Providence Hospital-Southfield Cancer Center

Southfield, Michigan, 48075, United States

Location

Munson Medical Center

Traverse City, Michigan, 49684, United States

Location

William Beaumont Hospital - Troy

Troy, Michigan, 48098, United States

Location

Saint John Macomb-Oakland Hospital

Warren, Michigan, 48093, United States

Location

Sanford Clinic North-Bemidgi

Bemidji, Minnesota, 56601, United States

Location

Essentia Health Saint Joseph's Medical Center

Brainerd, Minnesota, 56401, United States

Location

Fairview Ridges Hospital

Burnsville, Minnesota, 55337, United States

Location

Mercy Hospital

Coon Rapids, Minnesota, 55433, United States

Location

Essentia Health Cancer Center

Duluth, Minnesota, 55805, United States

Location

Essentia Health Saint Mary's Medical Center

Duluth, Minnesota, 55805, United States

Location

Miller-Dwan Hospital

Duluth, Minnesota, 55805, United States

Location

Fairview-Southdale Hospital

Edina, Minnesota, 55435, United States

Location

Lake Region Healthcare Corporation-Cancer Care

Fergus Falls, Minnesota, 56537, United States

Location

Unity Hospital

Fridley, Minnesota, 55432, United States

Location

Hutchinson Area Health Care

Hutchinson, Minnesota, 55350, United States

Location

Minnesota Oncology Hematology PA-Maplewood

Maplewood, Minnesota, 55109, United States

Location

Saint John's Hospital - Healtheast

Maplewood, Minnesota, 55109, United States

Location

Abbott-Northwestern Hospital

Minneapolis, Minnesota, 55407, United States

Location

Hennepin County Medical Center

Minneapolis, Minnesota, 55415, United States

Location

Health Partners Inc

Minneapolis, Minnesota, 55454, United States

Location

New Ulm Medical Center

New Ulm, Minnesota, 56073, United States

Location

North Memorial Medical Health Center

Robbinsdale, Minnesota, 55422, United States

Location

Metro Minnesota Community Oncology Research Consortium

Saint Louis Park, Minnesota, 55416, United States

Location

Park Nicollet Clinic - Saint Louis Park

Saint Louis Park, Minnesota, 55416, United States

Location

Regions Hospital

Saint Paul, Minnesota, 55101, United States

Location

United Hospital

Saint Paul, Minnesota, 55102, United States

Location

Saint Francis Regional Medical Center

Shakopee, Minnesota, 55379, United States

Location

Lakeview Hospital

Stillwater, Minnesota, 55082, United States

Location

Ridgeview Medical Center

Waconia, Minnesota, 55387, United States

Location

Rice Memorial Hospital

Willmar, Minnesota, 56201, United States

Location

Minnesota Oncology Hematology PA-Woodbury

Woodbury, Minnesota, 55125, United States

Location

University of Mississippi Medical Center

Jackson, Mississippi, 39216, United States

Location

Family Cancer Center-Oxford

Oxford, Mississippi, 38655, United States

Location

Singing River Hospital

Pascagoula, Mississippi, 39581, United States

Location

Family Cancer Center-Southhaven

Southaven, Mississippi, 38671, United States

Location

Baptist Memorial Hospital-Desoto

Southhaven, Mississippi, 38671, United States

Location

Parkland Health Center-Bonne Terre

Bonne Terre, Missouri, 63628, United States

Location

CoxHealth Cancer Center

Branson, Missouri, 65616, United States

Location

Saint Francis Medical Center

Cape Girardeau, Missouri, 63703, United States

Location

Southeast Cancer Center

Cape Girardeau, Missouri, 63703, United States

Location

University of Missouri - Ellis Fischel

Columbia, Missouri, 65212, United States

Location

Centerpoint Medical Center LLC

Independence, Missouri, 64057, United States

Location

Capital Region Medical Center-Goldschmidt Cancer Center

Jefferson City, Missouri, 65109, United States

Location

Freeman Health System

Joplin, Missouri, 64804, United States

Location

Mercy Hospital-Joplin

Joplin, Missouri, 64804, United States

Location

Saint Luke's Hospital of Kansas City

Kansas City, Missouri, 64111, United States

Location

Heartland Hematology and Oncology Associates Incorporated

Kansas City, Missouri, 64118, United States

Location

Research Medical Center

Kansas City, Missouri, 64132, United States

Location

Saint Luke's East - Lee's Summit

Lee's Summit, Missouri, 64086, United States

Location

Liberty Radiation Oncology Center

Liberty, Missouri, 64068, United States

Location

Delbert Day Cancer Institute at PCRMC

Rolla, Missouri, 65401, United States

Location

Saint John's Clinic-Rolla-Cancer and Hematology

Rolla, Missouri, 65401, United States

Location

Heartland Regional Medical Center

Saint Joseph, Missouri, 64506, United States

Location

Sainte Genevieve County Memorial Hospital

Sainte Genevieve, Missouri, 63670, United States

Location

Cancer Research for the Ozarks NCORP

Springfield, Missouri, 65804, United States

Location

Mercy Hospital Springfield

Springfield, Missouri, 65804, United States

Location

CoxHealth South Hospital

Springfield, Missouri, 65807, United States

Location

Saint Louis Cancer and Breast Institute-South City

St Louis, Missouri, 63109, United States

Location

Missouri Baptist Medical Center

St Louis, Missouri, 63131, United States

Location

Mercy Hospital Saint Louis

St Louis, Missouri, 63141, United States

Location

Missouri Baptist Sullivan Hospital

Sullivan, Missouri, 63080, United States

Location

Missouri Baptist Outpatient Center-Sunset Hills

Sunset Hills, Missouri, 63127, United States

Location

Billings Clinic Cancer Center

Billings, Montana, 59101, United States

Location

Montana Cancer Consortium NCORP

Billings, Montana, 59101, United States

Location

Saint Vincent Healthcare

Billings, Montana, 59101, United States

Location

Bozeman Deaconess Hospital

Bozeman, Montana, 59715, United States

Location

Saint James Community Hospital and Cancer Treatment Center

Butte, Montana, 59701, United States

Location

Benefis Healthcare- Sletten Cancer Institute

Great Falls, Montana, 59405, United States

Location

Saint Peter's Community Hospital

Helena, Montana, 59601, United States

Location

Kalispell Regional Medical Center

Kalispell, Montana, 59901, United States

Location

Montana Cancer Specialists

Missoula, Montana, 59802, United States

Location

Saint Patrick Hospital - Community Hospital

Missoula, Montana, 59802, United States

Location

Community Medical Hospital

Missoula, Montana, 59804, United States

Location

CHI Health Good Samaritan

Kearney, Nebraska, 68847, United States

Location

Nebraska Hematology and Oncology

Lincoln, Nebraska, 68506, United States

Location

Nebraska Cancer Research Center

Lincoln, Nebraska, 68510, United States

Location

Southeast Nebraska Cancer Center

Lincoln, Nebraska, 68510, United States

Location

Faith Regional Medical Offices West

Norfolk, Nebraska, 68701, United States

Location

Great Plains Regional Medical Center

North Platte, Nebraska, 69103, United States

Location

Missouri Valley Cancer Consortium

Omaha, Nebraska, 68106, United States

Location

Alegent Health Immanuel Medical Center

Omaha, Nebraska, 68122, United States

Location

Alegent Health Bergan Mercy Medical Center

Omaha, Nebraska, 68124, United States

Location

Oncology Hematology West

Omaha, Nebraska, 68124, United States

Location

Alegent Health Lakeside Hospital

Omaha, Nebraska, 68130, United States

Location

Oncology Hematology West PC

Omaha, Nebraska, 68130, United States

Location

Urology Cancer Center PC

Omaha, Nebraska, 68130, United States

Location

Creighton University Medical Center

Omaha, Nebraska, 68131, United States

Location

Regional West Medical Center

Scottsbluff, Nebraska, 69361, United States

Location

Cancer and Blood Specialists-Henderson

Henderson, Nevada, 89052, United States

Location

Comprehensive Cancer Centers of Nevada - Henderson

Henderson, Nevada, 89052, United States

Location

Las Vegas Cancer Center-Henderson

Henderson, Nevada, 89052, United States

Location

21st Century Oncology - Henderson

Henderson, Nevada, 89074, United States

Location

Comprehensive Cancer Centers of Nevada-Southeast Henderson

Henderson, Nevada, 89074, United States

Location

University Medical Center of Southern Nevada

Las Vegas, Nevada, 89102, United States

Location

Cancer and Blood Specialists-Shadow

Las Vegas, Nevada, 89106, United States

Location

Nevada Cancer Research Foundation CCOP

Las Vegas, Nevada, 89106, United States

Location

Radiation Oncology Centers of Nevada Central

Las Vegas, Nevada, 89106, United States

Location

21st Century Oncology

Las Vegas, Nevada, 89109, United States

Location

HealthCare Partners Medical Group Oncology/Hematology-Maryland Parkway

Las Vegas, Nevada, 89109, United States

Location

HealthCare Partners Medical Group Oncology/Hematology-San Martin

Las Vegas, Nevada, 89113, United States

Location

Radiation Oncology Centers of Nevada Southeast

Las Vegas, Nevada, 89119, United States

Location

Cancer Therapy and Integrative Medicine

Las Vegas, Nevada, 89121, United States

Location

Cancer and Blood Specialists-Tenaya

Las Vegas, Nevada, 89128, United States

Location

Comprehensive Cancer Centers of Nevada - Northwest

Las Vegas, Nevada, 89128, United States

Location

HealthCare Partners Medical Group Oncology/Hematology-Tenaya

Las Vegas, Nevada, 89128, United States

Location

Comprehensive Cancer Centers of Nevada-Summerlin

Las Vegas, Nevada, 89144, United States

Location

Las Vegas Cancer Center-Medical Center

Las Vegas, Nevada, 89148-2405, United States

Location

21st Century Oncology - Fort Apache

Las Vegas, Nevada, 89148, United States

Location

Cancer and Blood Specialists-Fort Apache

Las Vegas, Nevada, 89148, United States

Location

Comprehensive Cancer Centers of Nevada

Las Vegas, Nevada, 89148, United States

Location

HealthCare Partners Medical Group Oncology/Hematology-Centennial Hills

Las Vegas, Nevada, 89149, United States

Location

Comprehensive Cancer Centers of Nevada - Central Valley

Las Vegas, Nevada, 89169, United States

Location

21st Century Oncology - Vegas Tenaya

Las Vegas, Nevada, 89182, United States

Location

Renown Regional Medical Center

Reno, Nevada, 89502, United States

Location

Alpine Hematology-Oncology

Reno, Nevada, 89503, United States

Location

Saint Mary's Regional Medical Center

Reno, Nevada, 89503, United States

Location

Reno Oncology Consultants

Reno, Nevada, 89519, United States

Location

Wentworth-Douglass Hospital

Dover, New Hampshire, 03820, United States

Location

Portsmouth Regional Hospital

Portsmouth, New Hampshire, 03802, United States

Location

AtlantiCare Surgery Center

Egg Harbor, New Jersey, 08234, United States

Location

Saint Peter's University Hospital

New Brunswick, New Jersey, 08901, United States

Location

Newark Beth Israel Medical Center

Newark, New Jersey, 07112, United States

Location

Capital Health Medical Center-Hopewell

Pennington, New Jersey, 08534, United States

Location

Inspira Medical Center Vineland

Vineland, New Jersey, 08360, United States

Location

Inspira Medical Center Woodbury

Woodbury, New Jersey, 08096, United States

Location

University of New Mexico Cancer Center

Albuquerque, New Mexico, 87102, United States

Location

Hematology Oncology Associates of Central New York-Auburn

Auburn, New York, 13021, United States

Location

Roswell Park Cancer Institute

Buffalo, New York, 14263, United States

Location

Mary Imogene Bassett Hospital

Cooperstown, New York, 13326, United States

Location

Hematology Oncology Associates of Central New York-East Syracuse

East Syracuse, New York, 13057, United States

Location

Elmhurst Hospital Center

Elmhurst, New York, 11373, United States

Location

Arnot Ogden Medical Center/Falck Cancer Center

Elmira, New York, 14905, United States

Location

Queens Hospital Center

Jamaica, New York, 11432, United States

Location

Orange Regional Medical Center

Middletown, New York, 10940, United States

Location

Columbia University/Herbert Irving Cancer Center

New York, New York, 10032, United States

Location

Highland Hospital

Rochester, New York, 14620, United States

Location

University of Rochester

Rochester, New York, 14642, United States

Location

Hematology Oncology Associates of Central New York-Rome

Rome, New York, 13440, United States

Location

Staten Island University Hospital

Staten Island, New York, 10305, United States

Location

State University of New York Upstate Medical University

Syracuse, New York, 13210, United States

Location

Hematology Oncology Associates of Central New York-Onondaga Hill

Syracuse, New York, 13215, United States

Location

Lincoln Medical and Mental Health Center

The Bronx, New York, 10451, United States

Location

Dickstein Cancer Treatment Center

White Plains, New York, 10601, United States

Location

Randolph Hospital

Asheboro, North Carolina, 27203, United States

Location

Cancer Care of Western North Carolina

Asheville, North Carolina, 28801, United States

Location

Mission Hospital-Memorial Campus

Asheville, North Carolina, 28801, United States

Location

Hope Women's Cancer Centers-Asheville

Asheville, North Carolina, 28816, United States

Location

Gaston Hematology and Oncology Associates-Belmont

Belmont, North Carolina, 28012, United States

Location

Southeastern Medical Oncology Center-Clinton

Clinton, North Carolina, 28328, United States

Location

CaroMont Regional Medical Center

Gastonia, North Carolina, 28054, United States

Location

Gaston Hematology and Oncology Associates

Gastonia, North Carolina, 28054, United States

Location

Southeastern Medical Oncology Center-Goldsboro

Goldsboro, North Carolina, 27534, United States

Location

Wayne Memorial Hospital

Goldsboro, North Carolina, 27534, United States

Location

Cone Health Cancer Center

Greensboro, North Carolina, 27403, United States

Location

Hendersonville Hematology and Oncology at Pardee

Hendersonville, North Carolina, 28791, United States

Location

Margaret R Pardee Memorial Hospital

Hendersonville, North Carolina, 28791, United States

Location

Park Ridge Hospital Breast Health Center

Hendersonville, North Carolina, 28792, United States

Location

Southeastern Medical Oncology Center-Jacksonville

Jacksonville, North Carolina, 28546, United States

Location

Novant Health Oncology Specialists-Kernersville

Kernersville, North Carolina, 27284, United States

Location

Kinston Medical Specialists PA

Kinston, North Carolina, 28501, United States

Location

Cape Fear Cancer Specialists-Leland

Leland, North Carolina, 28451, United States

Location

Novant Health Oncology Specialists-Mount Airy

Mount Airy, North Carolina, 27030, United States

Location

FirstHealth of the Carolinas-Moore Regional Hosiptal

Pinehurst, North Carolina, 28374, United States

Location

Annie Penn Memorial Hospital

Reidsville, North Carolina, 27320, United States

Location

Carolina Oncology Associates PA

Salisbury, North Carolina, 28144, United States

Location

Cleveland Hematology and Oncology Associates PC

Shelby, North Carolina, 28150, United States

Location

Novant Health Oncology Specialists-Statesville

Statesville, North Carolina, 28625, United States

Location

Iredell Memorial Hospital

Statesville, North Carolina, 28677, United States

Location

Novant Health Oncology Specialists-Davidson County

Thomasville, North Carolina, 27360, United States

Location

Marion L Shepard Cancer Center at Vidant Beaufort Hospital

Washington, North Carolina, 27889, United States

Location

Novant Health Oncology Specialists-Wilkesboro

Wilkesboro, North Carolina, 28659, United States

Location

Cape Fear Cancer Specialists

Wilmington, North Carolina, 28401, United States

Location

New Hanover Regional Medical Center/Zimmer Cancer Center

Wilmington, North Carolina, 28401, United States

Location

Southeastern Medical Oncology Center-Wilson

Wilson, North Carolina, 27893, United States

Location

Novant Health Forsyth Medical Center

Winston-Salem, North Carolina, 27103, United States

Location

Novant Health Oncology Specialists

Winston-Salem, North Carolina, 27103, United States

Location

Winston-Salem Health Care

Winston-Salem, North Carolina, 27103, United States

Location

Southeast Clinical Oncology Research (SCOR) Consortium NCORP

Winston-Salem, North Carolina, 27104, United States

Location

Sanford Bismarck Medical Center

Bismarck, North Dakota, 58501, United States

Location

Essentia Health Cancer Center-South University Clinic

Fargo, North Dakota, 58103, United States

Location

Roger Maris Cancer Center

Fargo, North Dakota, 58122, United States

Location

Sanford Clinic North-Fargo

Fargo, North Dakota, 58122, United States

Location

Sanford Medical Center-Fargo

Fargo, North Dakota, 58122, United States

Location

Altru Cancer Center

Grand Forks, North Dakota, 58201, United States

Location

Trinity Cancer Care Center

Minot, North Dakota, 58701, United States

Location

Akron General Medical Center

Akron, Ohio, 44307, United States

Location

Strecker Cancer Center-Belpre

Belpre, Ohio, 45714, United States

Location

Toledo Clinic Cancer Centers-Bowling Green

Bowling Green, Ohio, 43402, United States

Location

Adena Regional Medical Center

Chillicothe, Ohio, 45601, United States

Location

Oncology Hematology Care Inc-Eden Park

Cincinnati, Ohio, 45202, United States

Location

Oncology Hematology Care Inc-Mercy West

Cincinnati, Ohio, 45211, United States

Location

Oncology Hematology Care Inc - Anderson

Cincinnati, Ohio, 45230, United States

Location

Oncology Hematology Care Inc-Kenwood

Cincinnati, Ohio, 45236, United States

Location

Oncology Hematology Care Inc-Blue Ash

Cincinnati, Ohio, 45242, United States

Location

Columbus Oncology and Hematology Associates Inc

Columbus, Ohio, 43214, United States

Location

Riverside Methodist Hospital

Columbus, Ohio, 43214, United States

Location

Columbus NCI Community Oncology Research Program

Columbus, Ohio, 43215, United States

Location

Grant Medical Center

Columbus, Ohio, 43215, United States

Location

The Mark H Zangmeister Center

Columbus, Ohio, 43219, United States

Location

Mount Carmel Health Center West

Columbus, Ohio, 43222, United States

Location

Doctors Hospital

Columbus, Ohio, 43228, United States

Location

Grandview Hospital

Dayton, Ohio, 45405, United States

Location

Good Samaritan Hospital - Dayton

Dayton, Ohio, 45406, United States

Location

Miami Valley Hospital

Dayton, Ohio, 45409, United States

Location

Samaritan North Health Center

Dayton, Ohio, 45415, United States

Location

Dayton NCI Community Oncology Research Program

Dayton, Ohio, 45420, United States

Location

Delaware Health Center-Grady Cancer Center

Delaware, Ohio, 43015, United States

Location

Delaware Radiation Oncology

Delaware, Ohio, 43015, United States

Location

Grady Memorial Hospital

Delaware, Ohio, 43015, United States

Location

Oncology Hematology Care Inc-Healthplex

Fairfield, Ohio, 45014, United States

Location

Blanchard Valley Hospital

Findlay, Ohio, 45840, United States

Location

Atrium Medical Center-Middletown Regional Hospital

Franklin, Ohio, 45005-1066, United States

Location

Wayne Hospital

Greenville, Ohio, 45331, United States

Location

Kettering Medical Center

Kettering, Ohio, 45429, United States

Location

Fairfield Medical Center

Lancaster, Ohio, 43130, United States

Location

Lancaster Radiation Oncology

Lancaster, Ohio, 43130, United States

Location

Saint Rita's Medical Center

Lima, Ohio, 45801, United States

Location

Lima Memorial Hospital

Lima, Ohio, 45804, United States

Location

Marietta Memorial Hospital

Marietta, Ohio, 45750, United States

Location

OneHealth Marion General Hospital

Marion, Ohio, 43302, United States

Location

Toledo Clinic Cancer Centers-Maumee

Maumee, Ohio, 43537, United States

Location

Toledo Radiation Oncology at Northwest Ohio Onocolgy Center

Maumee, Ohio, 43537, United States

Location

Knox Community Hospital

Mount Vernon, Ohio, 43050, United States

Location

Licking Memorial Hospital

Newark, Ohio, 43055, United States

Location

Newark Radiation Oncology

Newark, Ohio, 43055, United States

Location

Saint Charles Hospital

Oregon, Ohio, 43616, United States

Location

Toledo Clinic Cancer Centers-Oregon

Oregon, Ohio, 43616, United States

Location

Southern Ohio Medical Center

Portsmouth, Ohio, 45662, United States

Location

Springfield Regional Medical Center

Springfield, Ohio, 45505, United States

Location

Flower Hospital

Sylvania, Ohio, 43560, United States

Location

Mercy Hospital of Tiffin

Tiffin, Ohio, 44883, United States

Location

The Toledo Hospital/Toledo Children's Hospital

Toledo, Ohio, 43606, United States

Location

Saint Vincent Mercy Medical Center

Toledo, Ohio, 43608, United States

Location

University of Toledo

Toledo, Ohio, 43614, United States

Location

Toledo Community Hospital Oncology Program CCOP

Toledo, Ohio, 43617, United States

Location

Mercy Saint Anne Hospital

Toledo, Ohio, 43623, United States

Location

Toledo Clinic Cancer Centers-Toledo

Toledo, Ohio, 43623, United States

Location

Upper Valley Medical Center

Troy, Ohio, 45373, United States

Location

Fulton County Health Center

Wauseon, Ohio, 43567, United States

Location

Saint Ann's Hospital

Westerville, Ohio, 43081, United States

Location

Greene Memorial Hospital

Xenia, Ohio, 45385, United States

Location

Genesis Healthcare System Cancer Care Center

Zanesville, Ohio, 43701, United States

Location

Natalie Warren Bryant Cancer Center at Saint Francis

Tulsa, Oklahoma, 74136, United States

Location

Warren Clinic Oncology-Tulsa

Tulsa, Oklahoma, 74146, United States

Location

Clackamas Radiation Oncology Center

Clackamas, Oregon, 97015, United States

Location

Good Samaritan Hospital

Corvallis, Oregon, 97330, United States

Location

Providence Milwaukie Hospital

Milwaukie, Oregon, 97222, United States

Location

Providence Newberg Medical Center

Newberg, Oregon, 97132, United States

Location

Providence Willamette Falls Medical Center

Oregon City, Oregon, 97045, United States

Location

Providence Portland Medical Center

Portland, Oregon, 97213, United States

Location

Providence Saint Vincent Medical Center

Portland, Oregon, 97225, United States

Location

Kaiser Permanente Northwest

Portland, Oregon, 97227, United States

Location

Oregon Health and Science University

Portland, Oregon, 97239, United States

Location

Lehigh Valley Hospital-Cedar Crest

Allentown, Pennsylvania, 18103, United States

Location

Geisinger Medical Center

Danville, Pennsylvania, 17822, United States

Location

Doylestown Hospital

Doylestown, Pennsylvania, 18901, United States

Location

Easton Hospital

Easton, Pennsylvania, 18042, United States

Location

Geisinger Medical Center-Cancer Center Hazleton

Hazleton, Pennsylvania, 18201, United States

Location

Penn State Milton S Hershey Medical Center

Hershey, Pennsylvania, 17033-0850, United States

Location

Geisinger Medical Oncology-Lewisburg

Lewisburg, Pennsylvania, 17837, United States

Location

Lewistown Hospital

Lewistown, Pennsylvania, 17044, United States

Location

Holy Redeemer Hospital and Medical Center

Meadowbrook, Pennsylvania, 19046, United States

Location

Phoenixville Hospital

Phoenixville, Pennsylvania, 19460, United States

Location

Pottstown Memorial Medical Center

Pottstown, Pennsylvania, 19464, United States

Location

Geisinger Medical Oncology-Pottsville

Pottsville, Pennsylvania, 17901, United States

Location

Geisinger Medical Group

State College, Pennsylvania, 16801, United States

Location

Chester County Hospital

West Chester, Pennsylvania, 19380, United States

Location

Reading Hospital

West Reading, Pennsylvania, 19611, United States

Location

Geisinger Wyoming Valley/Henry Cancer Center

Wilkes-Barre, Pennsylvania, 18711, United States

Location

Susquehanna Cancer Center

Williamsport, Pennsylvania, 17701, United States

Location

AnMed Health Cancer Center

Anderson, South Carolina, 29621, United States

Location

Beaufort Memorial Hospital

Beaufort, South Carolina, 29902, United States

Location

Roper Hospital

Charleston, South Carolina, 29401, United States

Location

Charleston Hematology Oncology Associates-Roper

Charleston, South Carolina, 29403, United States

Location

Lowcountry Hematology Oncology PA-North Charleston

Charleston, South Carolina, 29406, United States

Location

Charleston Hematology Oncology Associates PA-St. Francis

Charleston, South Carolina, 29414, United States

Location

Lowcountry Hematology Oncology PA-West Ashley

Charleston, South Carolina, 29414, United States

Location

Greenville Health System Cancer Institute-Easley

Easley, South Carolina, 29640, United States

Location

McLeod Regional Medical Center

Florence, South Carolina, 29506, United States

Location

Saint Francis Hospital

Greenville, South Carolina, 29601, United States

Location

Greenville Health System Cancer Institute-Andrews

Greenville, South Carolina, 29605, United States

Location

Greenville Health System Cancer Institute-Butternut

Greenville, South Carolina, 29605, United States

Location

Greenville Health System Cancer Institute-Faris

Greenville, South Carolina, 29605, United States

Location

Greenville Memorial Hospital

Greenville, South Carolina, 29605, United States

Location

Greenville Health System Cancer Institute-Eastside

Greenville, South Carolina, 29615, United States

Location

Self Regional Healthcare

Greenwood, South Carolina, 29646, United States

Location

Greenville Health System Cancer Institute-Greer

Greer, South Carolina, 29650, United States

Location

Gibbs Cancer Center-Pelham

Greer, South Carolina, 29651, United States

Location

Lowcountry Hematology Oncology PA-Mount Pleasant

Mt. Pleasant, South Carolina, 29464, United States

Location

Greenville Health System Cancer Institute-Seneca

Seneca, South Carolina, 29672, United States

Location

Spartanburg Medical Center

Spartanburg, South Carolina, 29303, United States

Location

Greenville Health System Cancer Institute-Spartanburg

Spartanburg, South Carolina, 29307, United States

Location

Rapid City Regional Hospital

Rapid City, South Dakota, 57701, United States

Location

Sanford Cancer Center-Oncology Clinic

Sioux Falls, South Dakota, 57104, United States

Location

Sanford USD Medical Center - Sioux Falls

Sioux Falls, South Dakota, 57117-5134, United States

Location

Boston Baskin Cancer Center-Bartlett

Bartlett, Tennessee, 38133, United States

Location

Baptist Memorial Hospital and Cancer Center-Memphis

Memphis, Tennessee, 38120, United States

Location

Family Cancer Center-Memphis

Memphis, Tennessee, 38120, United States

Location

The Don and Sybil Harrington Cancer Center

Amarillo, Texas, 79106, United States

Location

Texas Technology University

El Paso, Texas, 79905, United States

Location

Doctor's Hospital of Laredo

Laredo, Texas, 78041, United States

Location

American Fork Hospital / Huntsman Intermountain Cancer Center

American Fork, Utah, 84003, United States

Location

Sandra L Maxwell Cancer Center

Cedar City, Utah, 84720, United States

Location

Logan Regional Hospital

Logan, Utah, 84321, United States

Location

Intermountain Medical Center

Murray, Utah, 84107, United States

Location

McKay-Dee Hospital Center

Ogden, Utah, 84403, United States

Location

Utah Valley Regional Medical Center

Provo, Utah, 84604, United States

Location

Utah Cancer Specialists-Salt Lake City

Salt Lake City, Utah, 84106, United States

Location

LDS Hospital

Salt Lake City, Utah, 84143, United States

Location

Dixie Medical Center Regional Cancer Center

St. George, Utah, 84770, United States

Location

Central Vermont Medical Center/National Life Cancer Treatment

Berlin Corners, Vermont, 05602, United States

Location

University of Vermont College of Medicine

Burlington, Vermont, 05405, United States

Location

Kaiser Permanente-Burke Medical Center

Burke, Virginia, 22015, United States

Location

Sentara Martha Jefferson Hospital

Charlottesville, Virginia, 22901, United States

Location

IMG Hematology Oncology 8501

Fairfax, Virginia, 22031, United States

Location

Fredericksburg Oncology Inc

Fredericksburg, Virginia, 22401, United States

Location

Kaiser Permanente Tysons Corner Medical Center

McLean, Virginia, 22102, United States

Location

Bon Secours Saint Francis Medical Center

Midlothian, Virginia, 23114, United States

Location

Bon Secours Saint Mary's Hospital

Richmond, Virginia, 23226, United States

Location

Cancer Care Center at Island Hospital

Anacortes, Washington, 98221, United States

Location

MultiCare Auburn Medical Center

Auburn, Washington, 98001, United States

Location

Virginia Mason Bainbridge Island Medical Center

Bainbridge Island, Washington, 98110, United States

Location

Overlake Hospital Medical Center

Bellevue, Washington, 98004, United States

Location

PeaceHealth Saint Joseph Medical Center

Bellingham, Washington, 98225, United States

Location

Harrison HealthPartners Hematology and Oncology-Bremerton

Bremerton, Washington, 98310, United States

Location

Highline Medical Center-Main Campus

Burien, Washington, 98166, United States

Location

Swedish Medical Center-Edmonds

Edmonds, Washington, 98026, United States

Location

Virginia Mason Federal Way Medical Center

Federal Way, Washington, 98002, United States

Location

Tacoma/Valley Radiation Oncology Centers-Gig Harbor

Gig Harbor, Washington, 98332, United States

Location

MultiCare Gig Harbor Medical Park

Gig Harbor, Washington, 98335, United States

Location

Swedish Cancer Institute-Issaquah

Issaquah, Washington, 98029, United States

Location

Kadlec Clinic Hematology and Oncology

Kennewick, Washington, 99336, United States

Location

Northwest Cancer Clinic

Kennewick, Washington, 99336, United States

Location

PeaceHealth Saint John Medical Center

Longview, Washington, 98632, United States

Location

Virginia Mason Lynnwood Medical Center

Lynnwood, Washington, 98036, United States

Location

Skagit Valley Hospital

Mount Vernon, Washington, 98274, United States

Location

Harrison HealthPartners Hematology and Oncology-Poulsbo

Poulsbo, Washington, 98370, United States

Location

Peninsula Cancer Center

Poulsbo, Washington, 98370, United States

Location

MultiCare Good Samaritan Hospital

Puyallup, Washington, 98372, United States

Location

Tacoma/Valley Radiation Oncology Centers-Puyallup

Puyallup, Washington, 98372, United States

Location

Virginia Mason Medical Center

Seattle, Washington, 98101, United States

Location

Harborview Medical Center

Seattle, Washington, 98104, United States

Location

Minor and James Medical PLLC

Seattle, Washington, 98104, United States

Location

Swedish Medical Center-Ballard Campus

Seattle, Washington, 98107, United States

Location

Fred Hutchinson Cancer Research Center

Seattle, Washington, 98109, United States

Location

Group Health Cooperative-Seattle

Seattle, Washington, 98112, United States

Location

Swedish Medical Center-First Hill

Seattle, Washington, 98122-4307, United States

Location

University of Washington Medical Center

Seattle, Washington, 98195, United States

Location

United General Hospital

Sedro-Woolley, Washington, 98284, United States

Location

Cancer Care Northwest - Spokane South

Spokane, Washington, 99202, United States

Location

Evergreen Hematology and Oncology PS

Spokane, Washington, 99218, United States

Location

Tacoma/Valley Radiation Oncology Centers-Jackson Hall

Tacoma, Washington, 97405, United States

Location

MultiCare Tacoma General Hospital

Tacoma, Washington, 98405, United States

Location

Northwest NCI Community Oncology Research Program

Tacoma, Washington, 98405, United States

Location

Tacoma/Valley Radiation Oncology Centers-Saint Joe's

Tacoma, Washington, 98405, United States

Location

PeaceHealth Southwest Medical Center

Vancouver, Washington, 98664, United States

Location

Compass Oncology Vancouver

Vancouver, Washington, 98684, United States

Location

Wenatchee Valley Hospital and Clinics

Wenatchee, Washington, 98801, United States

Location

Langlade Hospital and Cancer Center

Antigo, Wisconsin, 54409, United States

Location

Marshfield Clinic-Chippewa Center

Chippewa Falls, Wisconsin, 54729, United States

Location

Marshfield Clinic Cancer Center at Sacred Heart

Eau Claire, Wisconsin, 54701, United States

Location

Saint Agnes Hospital/Agnesian Cancer Center

Fond du Lac, Wisconsin, 54935, United States

Location

Green Bay Oncology at Saint Vincent Hospital

Green Bay, Wisconsin, 54301-3526, United States

Location

Saint Vincent Hospital Cancer Center Green Bay

Green Bay, Wisconsin, 54301, United States

Location

Green Bay Oncology Limited at Saint Mary's Hospital

Green Bay, Wisconsin, 54303, United States

Location

Saint Vincent Hospital Cancer Center at Saint Mary's

Green Bay, Wisconsin, 54303, United States

Location

Mercy Health System

Janesville, Wisconsin, 53547, United States

Location

Gundersen Lutheran Medical Center

La Crosse, Wisconsin, 54601, United States

Location

Holy Family Memorial Hospital

Manitowoc, Wisconsin, 54221, United States

Location

Bay Area Medical Center

Marinette, Wisconsin, 54143, United States

Location

Marshfield Clinic

Marshfield, Wisconsin, 54449, United States

Location

Wheaton Franciscan Healthcare - Saint Joseph

Milwaukee, Wisconsin, 53210, United States

Location

Marshfield Clinic-Minocqua Center

Minocqua, Wisconsin, 54548, United States

Location

Cancer Center of Western Wisconsin

New Richmond, Wisconsin, 54017, United States

Location

Green Bay Oncology - Oconto Falls

Oconto Falls, Wisconsin, 54154, United States

Location

Marshfield Clinic at James Beck Cancer Center

Rhinelander, Wisconsin, 54501, United States

Location

Marshfield Clinic-Rice Lake Center

Rice Lake, Wisconsin, 54868, United States

Location

HSHS Saint Nicholas Hospital

Sheboygan, Wisconsin, 53081, United States

Location

Marshfield Clinic Cancer Care at Saint Michael's Hospital

Stevens Point, Wisconsin, 54481, United States

Location

Green Bay Oncology - Sturgeon Bay

Sturgeon Bay, Wisconsin, 54235, United States

Location

Aspirus Regional Cancer Center

Wausau, Wisconsin, 54401, United States

Location

Marshfield Clinic-Wausau Center

Wausau, Wisconsin, 54401, United States

Location

Marshfield Clinic - Weston Center

Weston, Wisconsin, 54476, United States

Location

Aspirus UW Cancer Center

Wisconsin Rapids, Wisconsin, 54494, United States

Location

Marshfield Clinic - Wisconsin Rapids Center

Wisconsin Rapids, Wisconsin, 54494, United States

Location

Rocky Mountain Oncology

Casper, Wyoming, 82609, United States

Location

Cheyenne Regional Medical Center-West

Cheyenne, Wyoming, 82001, United States

Location

Big Horn Basin Cancer Center

Cody, Wyoming, 82414, United States

Location

Billings Clinic-Cody

Cody, Wyoming, 82414, United States

Location

Welch Cancer Center

Sheridan, Wyoming, 82801, United States

Location

Related Publications (1)

• Henry NL, Unger JM, Schott AF, Fehrenbacher L, Flynn PJ, Prow DM, Sharer CW, Burton GV, Kuzma CS, Moseley A, Lew DL, Fisch MJ, Moinpour CM, Hershman DL, Wade JL 3rd. Randomized, Multicenter, Placebo-Controlled Clinical Trial of Duloxetine Versus Placebo for Aromatase Inhibitor-Associated Arthralgias in Early-Stage Breast Cancer: SWOG S1202. J Clin Oncol. 2018 Feb 1;36(4):326-332. doi: 10.1200/JCO.2017.74.6651. Epub 2017 Nov 14.

  PMID: 29136387 DERIVED

MeSH Terms

Conditions

Breast Neoplasms; Pain

Interventions

Duloxetine Hydrochloride

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Thiophenes; Sulfur Compounds; Organic Chemicals; Heterocyclic Compounds, 1-Ring; Heterocyclic Compounds

Results Point of Contact

• Title: Leukemia Committee Statistician
• Organization: SWOG Statistics and Data Management Center

amoseley@fredhutch.org

2066674623

Study Officials

• N. Lynn Henry, MD, PhD

  University of Michigan Rogel Cancer Center

  PRINCIPAL INVESTIGATOR

• Anne F. Schott, MD

  University of Michigan Rogel Cancer Center

  STUDY CHAIR

Publication Agreements

• PI is Sponsor Employee: No
• Restriction Type: GT60
• Restrictive Agreement: Yes

Study Design

• Study Type: interventional
• Phase: phase 3
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 11, 2012
• First Posted: May 15, 2012
• Study Start: May 15, 2013
• Primary Completion: December 1, 2016
• Study Completion: December 20, 2018
• Last Updated: December 16, 2022
• Results First Posted: February 28, 2018

Record last verified: 2022-12

Data Sharing

• IPD Sharing: Will share

Locations

US (714)