Trials Sponsors Conditions Drugs Pricing

Conditions

Stroke Myocardial Infarctions

Outcome Measures

Primary Outcomes (1)

PFA1
Platelet Function Analysis (PFA) lab results: PFA was performed using the PFA 100 device (Dade-Behring), which uses a higher sheer stress flow cytometry paradigm to measure the time in seconds to closing of an aperture. Normal is defined as \<172 seconds."
3-6 months (Collected once between regulalary scheduled follow-up visit between 3-6 months)

Study Arms (3)

Clopidogrel 75 mg

ACTIVE COMPARATOR

Clopidogrel 75 mg daily

Drug: Clopidogrel

Aspirin 81 mg

ACTIVE COMPARATOR

open-label Aspirin 81 mg daily

Drug: Aspirin 81 mg

Aspirin > 300mg

ACTIVE COMPARATOR

open-label Aspirin over 300 mg daily

Drug: Aspirin >300 mg

Interventions

ClopidogrelDrug

Clopidogrel 75 mg QD

Also known as: Plavix

Clopidogrel 75 mg

Aspirin 81 mgDrug

Aspirin 81mg QD

Also known as: Acetylsalicylic Acid, ASA

Aspirin 81 mg

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Patient must be taking Aspirin or Plavix
Patient must have had a stroke, TIA or cerebrovascular disease

You may not qualify if:

Sponsors & Collaborators

Northwestern University
Otherlead

Study Sites (1)

Northwestern University

Chicago, Illinois, 60611, United States

Related Publications (1)

Taylor TN, Davis PH, Torner JC, Holmes J, Meyer JW, Jacobson MF. Lifetime cost of stroke in the United States. Stroke. 1996 Sep;27(9):1459-66. doi: 10.1161/01.str.27.9.1459.
PMID: 8784113BACKGROUND

MeSH Terms

Conditions

StrokeMyocardial Infarction

Interventions

ClopidogrelAspirin

Condition Hierarchy (Ancestors)

Cerebrovascular DisordersBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesVascular DiseasesCardiovascular DiseasesMyocardial IschemiaHeart DiseasesInfarctionIschemia

Results Point of Contact

Title: Northwestern University
Organization: Northwestern University

Study Officials

Mark J Alberts, MD
Northwestern University
PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee: No
Restrictive Agreement: No

Enrollment

93 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: phase 2 3
Allocation: NON RANDOMIZED
Masking: NONE
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

August 3, 2011

First Posted

April 27, 2012

Study Start

July 2007

Date type not reported

This date has not been verified as actual or estimated.

Aspirin Resistance and Stroke Risk: Platelet Function Analysis in Patients With Ischemic Events

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

First Submitted

Study Completion

First Posted

Results Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (3)

Clopidogrel 75 mg

Aspirin 81 mg

Aspirin > 300mg

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Results Point of Contact

Study Officials

Publication Agreements

Enrollment

Study Design

Study Record Dates

Intervention Hierarchy (Ancestors)

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

First Submitted

Study Completion

First Posted

Results Posted

Conditions

Outcome Measures

Primary Outcomes (1)

Study Arms (3)

Clopidogrel 75 mg

Aspirin 81 mg

Aspirin > 300mg

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

Related Publications (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Results Point of Contact

Study Officials

Publication Agreements

Enrollment

Study Design

Study Record Dates

Intervention Hierarchy (Ancestors)

Source record

Locations