NCT01578096

Brief Summary

The primary aims of this study are to:

  1. 1.Tailor a diabetes stress management intervention for delivery by community health workers (CHWs) serving an urban Latino population.
  2. 2.Investigate the efficacy of the stress management intervention on glycemic control.
  3. 3.Investigate the efficacy of the stress management intervention on stress hormones, psychosocial functioning, and stress-glucose reactivity.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
107

participants targeted

Target at P50-P75 for not_applicable diabetes-mellitus-type-2

Timeline
Completed

Started May 2012

Longer than P75 for not_applicable diabetes-mellitus-type-2

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

April 12, 2012

Completed
4 days until next milestone

First Posted

Study publicly available on registry

April 16, 2012

Completed
15 days until next milestone

Study Start

First participant enrolled

May 1, 2012

Completed
2.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2014

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2015

Completed
Last Updated

April 1, 2020

Status Verified

March 1, 2020

Enrollment Period

2.6 years

First QC Date

April 12, 2012

Last Update Submit

March 30, 2020

Conditions

Keywords

Type 2 Diabetes

Outcome Measures

Primary Outcomes (3)

  • Hemoglobin A1c

    Blood will be drawn from participants and hemoglobin A1c levels will be measured

    Baseline

  • Hemoglobin A1c

    Blood will be drawn from participants and hemoglobin A1c levels will be measured

    9 weeks

  • Hemoglobin A1c

    Blood will be drawn from participants and hemoglobin A1c levels will be measured

    6 months

Secondary Outcomes (3)

  • Diabetes specific distress

    Baseline

  • Diabetes specific distress

    9 weeks

  • Diabetes specific distress

    6 months

Study Arms (2)

Diabetes education

NO INTERVENTION

Group-based diabetes education delivered to participants through community health workers

Diabetes education plus stress management

EXPERIMENTAL

Group-based diabetes education plus stress management delivered to participants through community health workers

Behavioral: stress management

Interventions

The study is a randomized, controlled,single-site, parallel group clinical trial comparing the effectiveness of CHW led diabetes education with CHW led diabetes education plus CHW led stress management in Latinos with Type 2 Diabetes.

Diabetes education plus stress management

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Latinos age 18 or older that are ambulatory
  • Spanish speaking
  • Diagnosed with type 2 diabetes for at least 1 year
  • Hemoglobin A1c levels greater than 7.0

You may not qualify if:

  • Medical instability or medical treatment requiring inpatient care
  • Diagnoses of bipolar disorder or thought disorder (or taking medications prescribed for either); current substance abuse or dependence disorder
  • Current suicidality or history of suicide attempt
  • History of psychiatric hospitalization
  • Taking antidepressant medications prescribed for the treatment of depression accompanied by either a) changes to the antidepressant regimen within previous 6 weeks, or b) anticipated changes to the regimen during period of study. Such patients will be deferred and re-evaluated for eligibility after 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Yale University

New Haven, Connecticut, United States

Location

Related Publications (4)

  • Bermudez-Millan A, Perez-Escamilla R, Lampert R, Feinn R, Damio G, Segura-Perez S, Chhabra J, Kanc K, Wagner JA. Night Eating Among Latinos With Diabetes: Exploring Associations With Heart Rate Variability, Eating Patterns, and Sleep. J Nutr Educ Behav. 2022 May;54(5):449-454. doi: 10.1016/j.jneb.2022.02.006.

  • Wagner J, Armeli S, Tennen H, Bermudez-Millan A, Wolpert H, Perez-Escamilla R. A daily study of stressors, continuously measured glucose, and diabetes symptoms in latinos with type 2 diabetes. J Behav Med. 2021 Feb;44(1):94-103. doi: 10.1007/s10865-020-00162-1. Epub 2020 Jun 3.

  • Bermudez-Millan A, Wagner JA, Feinn RS, Segura-Perez S, Damio G, Chhabra J, Perez-Escamilla R. Inflammation and Stress Biomarkers Mediate the Association between Household Food Insecurity and Insulin Resistance among Latinos with Type 2 Diabetes. J Nutr. 2019 Jun 1;149(6):982-988. doi: 10.1093/jn/nxz021.

  • Bermudez-Millan A, Perez-Escamilla R, Segura-Perez S, Damio G, Chhabra J, Osborn CY, Wagner J. Psychological Distress Mediates the Association between Food Insecurity and Suboptimal Sleep Quality in Latinos with Type 2 Diabetes Mellitus. J Nutr. 2016 Oct;146(10):2051-2057. doi: 10.3945/jn.116.231365. Epub 2016 Aug 3.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Officials

  • Rafael Pérez-Escamilla, Ph.D.

    Yale University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 12, 2012

First Posted

April 16, 2012

Study Start

May 1, 2012

Primary Completion

December 1, 2014

Study Completion

June 1, 2015

Last Updated

April 1, 2020

Record last verified: 2020-03

Locations