NCT01577420

Brief Summary

The aim of this study is to test a complementary therapy intervention (reflexology) that will assist in improving quality of life (QOL) for women undergoing chemotherapy for late stage (III or IV) breast cancer within the context of conventional medical care. Quality of life will be assessed via intermediate indicators: 1) physical indicators (greater physical functioning, lower presence of symptoms) 2) emotional indicators (greater spirituality, lower anxiety, and lower depressive symptomology); and the outcome indicator of quality of life.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
451

participants targeted

Target at P75+ for not_applicable breast-cancer

Timeline
Completed

Started Aug 2005

Longer than P75 for not_applicable breast-cancer

Geographic Reach
1 country

12 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 1, 2005

Completed
4.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 1, 2010

Completed
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2010

Completed
1.7 years until next milestone

First Submitted

Initial submission to the registry

April 12, 2012

Completed
1 day until next milestone

First Posted

Study publicly available on registry

April 13, 2012

Completed
Last Updated

April 13, 2012

Status Verified

April 1, 2012

Enrollment Period

4.7 years

First QC Date

April 12, 2012

Last Update Submit

April 12, 2012

Conditions

Keywords

ReflexologyBreast CancerComplementary

Outcome Measures

Primary Outcomes (1)

  • Health Related Quality of Life

    Baseline to week 13

Study Arms (3)

Group A

EXPERIMENTAL

Reflexology Sessions: One session per week performed by certified reflexologist for four consecutive weeks.

Other: Reflexology Sessions

Group B

PLACEBO COMPARATOR

Placebo Sessions: One session per week performed by research aide for four consecutive weeks.

Other: Placebo Sessions

Group C

NO INTERVENTION

Control; no foot sessions

Interventions

One session per week performed by certified reflexologist for four consecutive weeks.

Group A

One session per week performed by research aide for four consecutive weeks.

Group B

Eligibility Criteria

Age21 Years+
Sexfemale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Diagnosis of Stage III or IV breast cancer, or Stage I or II with Metastasis or Recurrence
  • Able to perform basic ADLs
  • Free of diagnosis of mental illness on chart
  • Able to speak and understand English
  • Access to a telephone
  • Receiving chemotherapy at intake into the study
  • Palliative Prognostic Score of 11 or lower
  • Oriented to time, place, and person as determined by nurse recruiter

You may not qualify if:

  • Receiving investigational new drug chemotherapy
  • Receiving hospice care at intake
  • Living in nursing home or similar facility
  • Bedridden
  • Undergoing bone marrow transplant
  • Regularly using foot massage
  • Regularly using reflexology
  • Regularly using pedicure with foot massage

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (12)

Evanston Northwestern

Evanston, Illinois, 60201, United States

Location

Mt. Clemens

Evanston, Illinois, 60201, United States

Location

Hurley Medical Center

Flint, Michigan, 48503, United States

Location

GLCI/McLaren

Flint, Michigan, 48532, United States

Location

St. Joseph Mercy Oakland Hospital

Grand Rapids, Michigan, 44405, United States

Location

St. Mary's Health Care Center

Grand Rapids, Michigan, 49503, United States

Location

Great Lakes Cancer Institute (GLCI) MSU

Lansing, Michigan, 48910, United States

Location

Sparrow Hospital

Lansing, Michigan, 48912, United States

Location

William Beaumont Hospital

Royal Oak, Michigan, 48073, United States

Location

William Beaumont Hospital-Troy Campus

Troy, Michigan, 48085, United States

Location

St. John Macomb

Warren, Michigan, 48093, United States

Location

Josephine Ford Cancer Care, Henry Ford Hospital

West Bloomfield, Michigan, 48323, United States

Location

Related Publications (4)

  • Sikorskii A, Wyatt G, Victorson D, Faulkner G, Rahbar MH. Methodological issues in trials of complementary and alternative medicine interventions. Nurs Res. 2009 Nov-Dec;58(6):444-51. doi: 10.1097/NNR.0b013e3181bf15fe.

    PMID: 19918155BACKGROUND
  • Rahbar MH, Wyatt G, Sikorskii A, Victorson D, Ardjomand-Hessabi M. Coordination and management of multisite complementary and alternative medicine (CAM) therapies: experience from a multisite reflexology intervention trial. Contemp Clin Trials. 2011 Sep;32(5):620-9. doi: 10.1016/j.cct.2011.05.015. Epub 2011 Jun 2.

    PMID: 21664296BACKGROUND
  • Wyatt G, Sikorskii A, Rahbar MH, Victorson D, Adams L. Intervention fidelity: aspects of complementary and alternative medicine research. Cancer Nurs. 2010 Sep-Oct;33(5):331-42. doi: 10.1097/NCC.0b013e3181d0b4b7.

    PMID: 20467309BACKGROUND
  • Sikorskii A, Wyatt GK, Siddiqi AE, Tamkus D. Recruitment and early retention of women with advanced breast cancer in a complementary and alternative medicine trial. Evid Based Complement Alternat Med. 2011;2011:734517. doi: 10.1093/ecam/nep051. Epub 2011 Feb 14.

MeSH Terms

Conditions

Breast Neoplasms

Condition Hierarchy (Ancestors)

Neoplasms by SiteNeoplasmsBreast DiseasesSkin DiseasesSkin and Connective Tissue Diseases

Study Officials

  • Gwen Wyatt, PhD, RN

    Michigan State University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

April 12, 2012

First Posted

April 13, 2012

Study Start

August 1, 2005

Primary Completion

April 1, 2010

Study Completion

August 1, 2010

Last Updated

April 13, 2012

Record last verified: 2012-04

Locations