NCT01572285

Brief Summary

The purpose of this study is to determine whether transforaminal dexamethasone injections are effective in the treatment of chronic Hemiplegic Shoulder Pain.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2011

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2011

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

April 3, 2012

Completed
3 days until next milestone

First Posted

Study publicly available on registry

April 6, 2012

Completed
25 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 1, 2012

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

November 1, 2012

Completed
Last Updated

April 6, 2012

Status Verified

March 1, 2012

Enrollment Period

7 months

First QC Date

April 3, 2012

Last Update Submit

April 5, 2012

Conditions

Keywords

HemiplegicShoulder PainTransforaminalTreatmentInterventional

Outcome Measures

Primary Outcomes (1)

  • Pain improvement after transforaminal injection using the Visual Analogue Scale (VAS)

    The primary outcome measures were pain measured using a visual analogue scale (VAS on a scale of 0≈10cm; where 0=no pain and 10=highest pain level during the last week).

    1 week and 3 months after treatment

Secondary Outcomes (1)

  • Algometry in shoulder muscles

    1 week and 3 months after treatment

Study Arms (2)

Sham

SHAM COMPARATOR

Sham arm received a simulation of transforaminal injection using a non-penetrating needle

Procedure: Sham

Transforaminal

EXPERIMENTAL

Subjects received TF with infiltration of lidocaine 1% 0.5mL and 1.5mL of Dexamethasone 10mg/ml

Procedure: transforaminal dexamethasone injection

Interventions

Subjects received transforaminal infiltration of lidocaine 1% 0.5mL and 1.5mL of Dexamethasone 10mg/ml

Also known as: dexamethasone, steroid, transforaminal, TF, TFESI
Transforaminal
ShamPROCEDURE

Sham procedure using a non-penetrating needle

Sham

Eligibility Criteria

Age50 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • months of shoulder pain following a stroke
  • hemiplegia or paresis after a cerebral stroke for at least 6 months
  • Shoulder pain greater than 4 in a visual analogue scale
  • to 65 years old

You may not qualify if:

  • inability to understand or answer the tools in the study
  • local inflammation or infection
  • History of malignancy
  • use of cardiac pacemaker
  • allergy to lidocaine or dexamethasone
  • disorders of coagulation

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of São Paulo General Hospital

São Paulo, São Paulo, 05408040, Brazil

RECRUITING

MeSH Terms

Conditions

Shoulder Pain

Interventions

DexamethasoneSteroidssalicylhydroxamic acid

Condition Hierarchy (Ancestors)

ArthralgiaJoint DiseasesMusculoskeletal DiseasesPainNeurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

PregnadienetriolsPregnadienesPregnanesFused-Ring CompoundsPolycyclic CompoundsSteroids, Fluorinated

Study Officials

  • Joao D Amadera, MD

    University of São Paulo General Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Joao D Amadera, MD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 3, 2012

First Posted

April 6, 2012

Study Start

October 1, 2011

Primary Completion

May 1, 2012

Study Completion

November 1, 2012

Last Updated

April 6, 2012

Record last verified: 2012-03

Locations