Chicago Urban Resiliency Building (CURB)

NCT01571011 | Completed

• 1 other identifier: RWJF 68177
• Study Type: interventional
• Target: 10
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to determine whether a culturally tailored, low-cost, primary care/internet based depression prevention intervention (CURB) is superior to wait-list control for African American and Hispanic youth in terms of depression-related outcomes. It is hypothesized that compared to teens in the wait-list control condition, teens in the CURB program will exhibit lower levels of depressed mood and/or more rapid changes in mood during the follow-up time.

Conditions

Major Depression

Keywords

Adolescent; Randomized Trial; Internet; Depressive Disorder; Primary Care; Prevention

Outcome Measures

Primary Outcomes (1)

• The Center for Epidemiological Studies of Depression (CES-D) Scale

  Change in CESD from baseline Change in CESD scale between and within groups across the 6 months and for each assessment point

  0, 3, 6 months

Secondary Outcomes (3)

• Cost effective outcome measures

  6 months

• Vulnerability

  6 months

• Protective factors

  6 months

Study Arms (2)

CURB Intervention

EXPERIMENTAL

The intervention is made up of 14 internet modules based on behavioral activation, cognitive behavioral therapy, and interpersonal psychotherapy as well as motivational interviews in the primary care setting (to enhance behavior change). It is suggested that an adolescent navigates through 2 modules a week. The motivational interviews with the physicians occur directly before and after the adolescent is exposed to the website (at baseline and 3 months) in the providers office. The parents of the enrolled adolescents are also invited to navigate through their own, 3 module, parent internet program.

Behavioral: CURB

CURB Intervention (Wait List)

EXPERIMENTAL

Same as the CURB Intervention arm, however, individuals assigned to this arm wait 3 months before receiving the intervention.

Behavioral: CURB

Interventions

CURB BEHAVIORAL

The intervention is made up of 14 internet modules based on behavioral activation, cognitive behavioral therapy, and interpersonal psychotherapy as well as motivational interviews in the primary care setting (to enhance behavior change). It is suggested that an adolescent navigates through 2 modules a week. The motivational interviews with the physicians occur directly before and after the adolescent is exposed to the website (at baseline and 3 months) in the providers office. The parents of the enrolled adolescents are also invited to navigate through their own, 3 module, parent internet program.

CURB Intervention; CURB Intervention (Wait List)

Eligibility Criteria

• Age: 13 Years - 17 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Adolescents:
• Male and female African American and Latino/a youth ages 13 -17 years old.

You may not qualify if:

• Parents:
• Parent of eligible adolescents
• Primary Care Physicians (PCPs):
• Physician at one of the four Mile Square Health Centers.
• Health Care Professionals:
• Employee at one of the four Mile Square Health Centers.
• Adolescents undergoing active treatment for depression \[Active treatment for depression is defined as receiving anti-depressant medication or counseling within one year of remission of symptoms from the most recent episode\]
• Adolescents meeting probable diagnostic criteria for the following: Major depression, Substance and alcohol abuse, Panic attacks, Generalized anxiety disorder, Eating disorders, History of treatment for bi-polar disorder or schizophrenia or who are at elevated risk for suicide (often have suicidal thoughts or recent intent)

Sponsors & Collaborators

• Benjamin Van Voorhees, MD, MPH: lead

Study Sites (1)

Mile Square Health Centers

Chicago, Illinois, 60612, United States

Location

Related Links

• Sponsor

MeSH Terms

Conditions

Depressive Disorder, Major; Depressive Disorder

Condition Hierarchy (Ancestors)

Mood Disorders; Mental Disorders

Study Officials

• Benjamin Van Voorhees, MD, MPH

  University of Illinois at Chicago

  PRINCIPAL INVESTIGATOR

• Monika Marko, MSS

  UIS

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Associate Professor of Pediatrics; Chief, Section of General Pediatrics and Adolescent Medicine; Director, TIKES Center Department of Pediatrics

Study Record Dates

• First Submitted: March 20, 2012
• First Posted: April 4, 2012
• Study Start: March 1, 2012
• Primary Completion: April 1, 2014
• Study Completion: April 1, 2014
• Last Updated: August 4, 2015

Record last verified: 2015-07

Locations

US (1)