NCT01569646

Brief Summary

Increased white blood cell count at the onset of an acute ST elevation myocardial infarction has been shown to be associated of increased incidence of heart failure and mortality. Now monocytes which are a subset of white blood cells may have a prognostic value for patients presenting with acute ST segment elevation myocardial infarction. A monocyte count of greater than 800/mm3 following acute myocardial infarction has been shown to be associated with increased incidence of left ventricular dysfunction. The investigators study would retrospectively collect data on patients with ST elevation myocardial infarction, looking for an association between high monocyte count and the culprit vessel causing the myocardial infarction. The investigators would also investigate whether monocytosis would be a marker of poor prognosis.

Trial Health

80
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
226

participants targeted

Target at P75+ for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2008

Completed
2.2 years until next milestone

First Submitted

Initial submission to the registry

June 2, 2010

Completed
1.8 years until next milestone

First Posted

Study publicly available on registry

April 3, 2012

Completed
Last Updated

April 3, 2012

Status Verified

March 1, 2012

First QC Date

June 2, 2010

Last Update Submit

March 30, 2012

Conditions

STEMI

Keywords

monocytesculprit vessels

Outcome Measures

Primary Outcomes (1)

  • Association between monocyte count and culprit vessel

    1 day

Secondary Outcomes (1)

  • clinical outcomes of troponin and monocyte in stemi patients

    0 - 6 months

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

STEMI patients,

You may qualify if:

  • STEMI

You may not qualify if:

  • Patients on antibiotics and steroids

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Staten Island University Hospital

Staten Island, New York, 10305, United States

Location

MeSH Terms

Conditions

ST Elevation Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial InfarctionMyocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Officials

  • Duccio Baldari, MD, FACC

    Staten Island University Hospital

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 2, 2010

First Posted

April 3, 2012

Study Start

April 1, 2008

Last Updated

April 3, 2012

Record last verified: 2012-03

Locations

US(1)