Comparison of Information Recorded in MINAP, GPRD and HES: a CALIBER Study
Comparison of the Information Recorded in the Myocardial Ischaemia National Audit Project, the General Practice Research Database and Hospital Episode Statistics: a CALIBER Study
2 other identifiers
observational
21,000
1 country
3
Brief Summary
Medical information is increasingly processed electronically. This study will describe the similarities and differences in the data recorded by different databases of electronic healthcare database. These will include the General Practice Research Database (GPRD) and the Myocardial Ischaemia National Audit Project (MINAP) and hospital episode statistics (HES).
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Dec 2011
Typical duration for all trials
3 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
December 1, 2011
CompletedFirst Submitted
Initial submission to the registry
March 30, 2012
CompletedFirst Posted
Study publicly available on registry
April 2, 2012
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 1, 2014
CompletedStudy Completion
Last participant's last visit for all outcomes
December 1, 2014
CompletedOctober 2, 2015
October 1, 2015
3 years
March 30, 2012
October 1, 2015
Conditions
Keywords
Study Arms (3)
GPRD MI
Myocardial infarction, as identified in the GPRD data.
MINAP MI
Myocardial infarction, as identified in MINAP data.
HES MI
Myocardial infarction, as identified in HES data.
Eligibility Criteria
The study population is comprised of "acceptable" patients registered at those GPRD practices that agreed to the linkage with MINAP and HES, whose practices are "up to standard" according to GPRD criteria. Practices taking part in the GPRD are chosen to be representative of UK practices, and 98% of people in the UK are registered with a GP. Therefore the GPRD should be a representative sample of the UK population.
You may qualify if:
- Aged 18+
- Patients in GPRD practices which are deemed "up to standard" by GPRD criteria
- Patients in GPRD whose practice agreed to be linked to the MINAP and HES datasets.
- Patients whose records are deemed "acceptable" by GPRD criteria
- Patients whose age and sex, as recorded in GPRD is the same as that recorded in HES and MINAP.
- Patients with evidence of myocardial infarction in one of the datasets (HES, MINAP, GPRD, ONS) between 1st January 2003 and 6th August 2009.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- London School of Hygiene and Tropical Medicinelead
- University College, Londoncollaborator
- General Practice Research Databasecollaborator
Study Sites (3)
London School of Hygiene and Tropical Medicine
London, WC1E 7HT, United Kingdom
General Practice Research Database
London, United Kingdom
University College, London
London, United Kingdom
Related Publications (1)
Herrett E, Shah AD, Boggon R, Denaxas S, Smeeth L, van Staa T, Timmis A, Hemingway H. Completeness and diagnostic validity of recording acute myocardial infarction events in primary care, hospital care, disease registry, and national mortality records: cohort study. BMJ. 2013 May 20;346:f2350. doi: 10.1136/bmj.f2350.
PMID: 23692896DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Research Degree Student
Study Record Dates
First Submitted
March 30, 2012
First Posted
April 2, 2012
Study Start
December 1, 2011
Primary Completion
December 1, 2014
Study Completion
December 1, 2014
Last Updated
October 2, 2015
Record last verified: 2015-10