Improving Depression Care for Elders: Coordinating Center

NCT01561105 | Completed DMC

• 1 other identifier: JAHF 98297
• Study Type: interventional
• Target: 1,801
• Locations: 0 countries
• Sites: N/A

Brief Summary

Purpose: To determine the effectiveness of the Improving Mood-Promoting Access to Collaborative Treatment(IMPACT) collaborative care management program for late-life depression.

Conditions

Major Depression; Dysthymic Disorder; Both Major Depression and Dysthymic Disorder

Outcome Measures

Primary Outcomes (1)

• Severity of depression symptoms

  Severity measured by the 21-item Hopkins Symptom Checklist.

Secondary Outcomes (1)

• Functioning

Study Arms (2)

IMPACT

EXPERIMENTAL

Other: IMPACT

Care as Usual

NO INTERVENTION

Patients received all depression care available to them as part of care as usual in the participating primary care clinics.

Interventions

IMPACT OTHER

IMPACT is a collaborative care management program for late-life depression

Also known as: Improving Mood-Promoting Access to Collaborative Treatment

IMPACT

Eligibility Criteria

• Age: 60 Years+
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Major depression or dysthymia as diagnosed by a structured diagnostic interview.
• Patient plans to receive primary care at the study clinic for the next year.

You may not qualify if:

• Age under 60.
• Current symptoms or history of psychosis or mania as determined by structured diagnostic interview.
• Cognitive impairment as defined by a score less than 23 on a Mini Mental Status Examination.
• Terminal illness - defined as having a life expectancy of less than 6 months.
• Active alcohol abuse as determined by a screening interview.
• High suicide risk as determined by current plan for suicide or a history of more than 3 prior suicide attempts in the past 10 years.

Sponsors & Collaborators

• University of California, Los Angeles: lead
• The John A. Hartford Foundation: collaborator
• California HealthCare Foundation: collaborator
• Hogg Foundation: collaborator
• Robert Wood Johnson Foundation: collaborator

Related Publications (2)

• Unutzer J, Katon W, Callahan CM, Williams JW Jr, Hunkeler E, Harpole L, Hoffing M, Della Penna RD, Noel PH, Lin EH, Arean PA, Hegel MT, Tang L, Belin TR, Oishi S, Langston C; IMPACT Investigators. Improving Mood-Promoting Access to Collaborative Treatment. Collaborative care management of late-life depression in the primary care setting: a randomized controlled trial. JAMA. 2002 Dec 11;288(22):2836-45. doi: 10.1001/jama.288.22.2836.

  PMID: 12472325 RESULT

• Stewart JC, Perkins AJ, Callahan CM. Effect of collaborative care for depression on risk of cardiovascular events: data from the IMPACT randomized controlled trial. Psychosom Med. 2014 Jan;76(1):29-37. doi: 10.1097/PSY.0000000000000022. Epub 2013 Dec 23.

  PMID: 24367124 DERIVED

MeSH Terms

Conditions

Depressive Disorder, Major; Dysthymic Disorder

Condition Hierarchy (Ancestors)

Depressive Disorder; Mood Disorders; Mental Disorders

Study Officials

• Jurgen Unutzer, MD, MPH

  University of Washington

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor and Vice-Chair of Psychiatry, Psychiatry and Behavioral Sciences

Study Record Dates

• First Submitted: March 20, 2012
• First Posted: March 22, 2012
• Study Start: January 1, 1999
• Primary Completion: June 1, 2004
• Study Completion: June 1, 2004
• Last Updated: March 28, 2012

Record last verified: 2012-03